[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100657362":3},{"organization":4,"outcomesModule":7,"designInfo":50,"detailedDescription":56,"studyPopulation":49,"armGroups":57,"interventions":68,"overallOfficials":72,"centralContacts":77,"locations":82,"responsibleParty":94,"collaborators":49,"id":97,"slug":98,"hasResults":99,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":49,"eligibilityCriteria":103,"healthyVolunteers":99,"sex":104,"minAge":105,"maxAge":106,"enrollmentInfo":107,"targetDuration":49,"studyType":110,"phases":111,"briefSummary":113,"conditions":114,"keywords":49,"overallStatus":118,"whyStopped":49,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":128},{"fullName":5,"class":6},"The University of Hong Kong","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":17,"otherOutcomes":49},[9,13,15],{"measure":10,"description":11,"timeFrame":12},"Fatigue","The Brief Fatigue Inventory (BFI) is used for assessing Fatigue levels. Scores range from 0 to 10, with higher scores indicating greater severity of Fatigue.","Baseline",{"measure":10,"description":11,"timeFrame":14},"1-week Post-intervention",{"measure":10,"description":11,"timeFrame":16},"1-month Follow-up",[18,21,22,23,26,27,28,31,32,34,37,38,39,42,43,44,47,48],{"measure":19,"description":20,"timeFrame":12},"Depression","The Depression subscale of Hospital Anxiety and Depression Scale (HADS-D) is used for assessing Depressive Symptoms. Scores range from 0 to 21, with higher scores indicating greater severity of Depressive Symptoms.",{"measure":19,"description":20,"timeFrame":14},{"measure":19,"description":20,"timeFrame":16},{"measure":24,"description":25,"timeFrame":12},"Anxiety","The Anxiety subscale of Hospital Anxiety and Depression Scale (HADS-A) is used for assessing Anxiety Symptoms. Scores range from 0 to 21, with higher scores indicating greater severity of Anxiety Symptoms.",{"measure":24,"description":25,"timeFrame":14},{"measure":24,"description":25,"timeFrame":16},{"measure":29,"description":30,"timeFrame":12},"Sleep Quality","The Pittsburgh Sleep Quality Index (PSQI) is used for assessing Sleep Quality. Scores range from 0 to 21, with higher scores indicating poorer Sleep Quality and greater severity of Sleep Disturbances.",{"measure":29,"description":30,"timeFrame":14},{"measure":29,"description":30,"timeFrame":33},"1-week Follow-up",{"measure":35,"description":36,"timeFrame":12},"Presence of Meaning in Life","The Presence of Meaning subscale of Meaning in Life Questionnaire (MLQ-P) is used for assessing the extent to which individuals experience presence of meaning and purpose in their lives. Scores range from 5 to 35, with higher scores indicating higher Presence of Meaning.",{"measure":35,"description":36,"timeFrame":14},{"measure":35,"description":36,"timeFrame":16},{"measure":40,"description":41,"timeFrame":12},"Search for Meaning","The Search of Meaning subscale of Meaning in Life Questionnaire (MLQ-S) is used for assessing how actively individuals seek meaning and purpose in their lives. Scores range from 5 to 35, with higher scores indicating greater search for meaning.",{"measure":40,"description":41,"timeFrame":14},{"measure":40,"description":41,"timeFrame":16},{"measure":45,"description":46,"timeFrame":12},"Quality of Life, measured by MQOL","The McGill Quality of Life Questionnaire (MQOL) is used for assessing Quality of Life. Scores range from 0 to 10, with higher scores indicating better Quality of Life.",{"measure":45,"description":46,"timeFrame":14},{"measure":45,"description":46,"timeFrame":16},null,{"allocation":51,"interventionModel":52,"interventionModelDescription":49,"primaryPurpose":53,"observationalModel":49,"timePerspective":49,"maskingInfo":54},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":55,"maskingDescription":49,"whoMasked":49},"NONE","Background:\n\nYoung Adult Cancer Survivors (YACS) refers to young adults aged 18-39 with a history of cancer, with \"survivor\" status defined as having completed primary treatment for cancer. YACS encompasses both survivors of Adolescent and Young Adult (AYA) cancer (defined as primary cancer onset at age of 15-39) and childhood cancer (defined as primary cancer onset at age of 0-14). According to statistics from the Hong Kong Cancer Registry, there were 1,471 new cases of AYA cancer and 111 cases of childhood cancer in 2023.\n\nStudies have found fatigue to be prevalent and particularly distressing among Young Adult Cancer Survivors (YACS): 1 in every 4 YACS continued to experience persistent chronic fatigue even after a median of 14 years since cancer diagnosis.\n\nIn this connection, we propose a brief meaning-making education program, grounded in Viktor Frankl's Existential Psychology, for facilitating fatigue management in post-treatment Young Adult Cancer Survivors.\n\nMethods:\n\nParticipants will be randomly assigned to intervention (2-session, in-person meaning-making education) or control (usual care) at a 1:1 ratio. This study is designed as open label since both interventionist and participants could not be blinded to meaning-making nature of the intervention versus control (no intervention). To prevent contamination, participants in the intervention arm will be advised to avoid discussing the intervention content with others.\n\nIntervention development process will be guided by a Faculty Member of the Viktor Frankl Institute of Logotherapy. Intervention will be delivered by a University lecturer upon completion of 105 hours of training as part of a certificate program at the Viktor Frankl Institute of Logotherapy. Throughout the study period, the interventionist will receive ongoing supervision from a locally registered counselling psychologist in Hong Kong.",[58,64],{"label":59,"type":60,"description":61,"interventionNames":62},"Meaning-making","EXPERIMENTAL","Subjects randomized to this experimental arm will receive the Intervention",[63],"Other: Meaning-making",{"label":65,"type":66,"description":67,"interventionNames":49},"Control","NO_INTERVENTION","Subjects randomized to this Control Group will not receive any Intervention.",[69],{"type":6,"name":59,"description":70,"armGroupLabels":71,"otherNames":49},"The proposed intervention will be an in-person, group-based, meaning-making wellness programme (two sessions, each 2 to 3-hr long), for Young Adult Cancer Survivors.\n\nIntervention content will be based on core philosophical tenets and concepts of Viktor Frankl's Existential Psychology. Activities include didactic teaching, group discussions, as well as reflective activities through audio-visual media such as visual stories, games, photos, videos and music.\n\nThe intervention does not involve psychotherapy.\n\nIntervention development process will be guided by a Faculty Member of the Viktor Frankl Institute of Logotherapy. Intervention will be delivered by a University lecturer upon completion of 105 hours of training as part of a certificate program at the Viktor Frankl Institute of Logotherapy. Throughout the study period, the interventionist will receive ongoing supervision from a locally registered counselling psychologist in Hong Kong.",[59],[73],{"name":74,"affiliation":75,"role":76},"Ki Sum Samson Wong, MSocSc, FHEA, FAcadMEd, AFAMEE","Li Ka Shing Faculty of Medicine","PRINCIPAL_INVESTIGATOR",[78],{"name":74,"role":79,"phone":80,"phoneExt":49,"email":81},"CONTACT","(852)39179309","samsonks@connect.hku.hk",[83],{"facility":5,"status":49,"city":84,"state":49,"zip":49,"country":84,"countryCode":85,"cosmosGeoPoint":86,"geoPoint":91,"contacts":92},"Hong Kong","HK",{"type":87,"coordinates":88},"Point",[89,90],114.17469,22.27832,{"lat":90,"lon":89},[93],{"name":74,"role":79,"phone":80,"phoneExt":49,"email":81},{"type":76,"investigatorFullName":95,"investigatorTitle":96,"investigatorAffiliation":5,"oldNameTitle":49,"oldOrganization":49},"Ki Sum Samson WONG","Assistant Lecturer, Li Ka Shing Faculty of Medicine","100657362","brief-meaning-making-for-young-adult-cancer-survivors-100657362",false,"NCT07836075","Brief Meaning-making for Young Adult Cancer Survivors","Brief Meaning-making Program for Young Adult Cancer Survivors (YACS): An Open-label Randomized Controlled Feasibility Study","Inclusion Criteria:\n\n* Cancer survivors currently aged 18-39, including who are currently either cancer-free, in remission, or receiving maintenance therapy.\n* Having completed primary cancer treatment for at least about 2 months.\n* Able to speak, read, and comprehend Cantonese, and able to comprehend English.\n* Ambulatory\n* No auditory, visual or language or reading disabilities (e.g. aphasia, deafness)\n* Able to complete online questionnaires.\n* Able to use laptop.\n* Willing to accept randomization.\n\nExclusion Criteria:\n\n* Current severe or untreated psychiatric disorder that would preclude participation in class activities.\n* Displaying any psychotic symptoms which would hinder class participation.\n* Having physical, sensory disabilities or cognitive impairment that would preclude face-to-face class. attendance and group-based interaction.\n* Unwilling to accept randomization.\n* Currently receiving any type of psychotherapy\n* Having received any Franklian existential psychology-related interventions, Logotherapy or Meaning-centred Psychotherapy before.\n\nRemark: Some inclusion and exclusion criteria are purposely omitted at this time to preserve scientific integrity. They will be included after the trial is complete.","ALL","18 Years","39 Years",{"count":108,"type":109},50,"ESTIMATED","INTERVENTIONAL",[112],"NA","The goal of this feasibility study is to learn if a brief meaning-making wellness intervention based on Viktor Frankl's Existential Psychology works to improve fatigue levels in Young Adult Cancer Survivors (YACS) who have completed primary treatment. The main questions it aims to answer are:\n\n* What would be the recruitment and retention rates?\n* What might the feedback from participants be?\n* Could there be any effects on fatigue and other related symptoms? Researchers will compare meaning-making to usual care (no intervention) to see if meaning-making works to improve fatigue and other symptoms in YACS.\n\nParticipants will:\n\n* Complete questionnaires (self-reported outcome measures) at baseline, 1-week post-intervention, and at 1-month follow-up.\n* Attend an in-person, two-session brief meaning-making program",[115,116,117],"Wellness Program","Cancer Survivorship","Adolescent and Young Adult Cancer Survivors","NOT_YET_RECRUITING","2026-09-17",{"date":121,"type":122},"2026-09-23","ACTUAL",{"date":124,"type":109},"2026-09-28",{"date":126,"type":109},"2027-09-30",{"name":5,"class":6},1]