[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100647019":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":29,"locations":39,"responsibleParty":56,"collaborators":11,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":11,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":11,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":78,"overallStatus":82,"whyStopped":11,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Tang-Du Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Care Pathway Group","EXPERIMENTAL",null,[13],"Behavioral: BSFS-Based Diarrhea Care Pathway",{"label":15,"type":16,"description":11,"interventionNames":17},"Routine Care Group","ACTIVE_COMPARATOR",[18],"Other: Routine ICU Enteral Nutrition Care",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"BEHAVIORAL","BSFS-Based Diarrhea Care Pathway","Standardized nursing pathway: stool assessment every 4 h using the Bristol Stool Form Scale, with graded interventions (monitoring frequency, infusion-rate adjustment, formula change, probiotics, perianal skin protection, stepwise feeding resumption) triggered by stool type 5\u002F6\u002F7. Applied to the Care Pathway Group.",[9],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"Routine ICU Enteral Nutrition Care","Standard ICU nursing for enteral nutrition without systematic BSFS assessment.",[15],[30,35],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},"Lu Li","CONTACT","+86 158 0928 5776","lilu455699299@163.com",{"name":36,"role":32,"phone":37,"phoneExt":11,"email":38},"Shuai Qiao","+86 13598089070","1255095003@qq.com",[40],{"facility":41,"status":11,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Department of Critical Care Medicine, Tangdu Hospital, Fourth Military Medical University","Xi'an","Shaanxi","710032","China","CN",{"type":48,"coordinates":49},"Point",[50,51],108.92861,34.25833,{"lat":51,"lon":50},[54,55],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},{"name":36,"role":32,"phone":37,"phoneExt":11,"email":38},{"type":57,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100647019","bristol-stool-scale-based-care-pathway-for-enteral-nutrition-associated-diarrhea-in-critically-ill-patients-100647019",false,"NCT07683364","Bristol Stool Scale-Based Care Pathway for Enteral Nutrition-Associated Diarrhea in Critically Ill Patients","Construction and Evaluation of a Bristol Stool Form Scale-Based Nursing Care Pathway for Enteral Nutrition-Associated Diarrhea in Critically Ill Patients: A Prospective, Randomized, Controlled, Single-Center Trial","Inclusion Criteria:\n\n* ICU critically ill patient (APACHE II score ≥15).\n* Receiving enteral nutrition via nasogastric or nasojejunal tube.\n* No diarrhea in the 24 hours before enrollment (stool frequency \\\u003C3\u002Fday or BSFS type \\\u003C5).\n* Written informed consent provided by the patient or legal representative.\n\nExclusion Criteria:\n\n* Known allergy to components of the enteral nutrition formula used.\n* Organic bowel disease such as inflammatory bowel disease or short bowel syndrome.\n* Pre-existing diarrhea at enrollment (≥3 stools\u002F24 h and BSFS type ≥5).\n* Severe hepatic insufficiency.\n* Clostridioides difficile infection or other stool-culture-confirmed infectious diarrhea.\n* Pregnant or lactating women.\n* Currently participating in another clinical study.\n* Any other condition deemed unsuitable by the investigator.","ALL","18 Years","80 Years",{"count":69,"type":70},60,"ESTIMATED","INTERVENTIONAL",[73],"NA","Enteral nutrition-associated diarrhea (ENAD) is one of the most common gastrointestinal complications in critically ill patients receiving enteral nutrition, with a reported incidence of 22.3%-63.1%. Current management lacks a standardized nursing process and relies on individual nurse experience. This study constructs a standardized nursing care pathway driven by the Bristol Stool Form Scale (BSFS) and evaluates, in a prospective randomized controlled design, whether it reduces the severity of ENAD compared with routine ICU care. Eligible mechanically fed ICU patients are randomized 1:1 to the care-pathway group or the routine-care group, observed for 7 days (D1-D7) with a follow-up assessment on D14. The primary endpoint is the Hart diarrhea score over the observation period.",[76,77],"Critical Illness","Diarrhea",[79,80,77,81],"Bristol Stool Form Scale","Enteral nutrition","Critically ill","NOT_YET_RECRUITING","2026-07-02",{"date":85,"type":86},"2026-07-06","ACTUAL",{"date":88,"type":70},"2026-06-15",{"date":90,"type":70},"2026-08-30",{"name":5,"class":6},1]