[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100651601":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":46,"responsibleParty":62,"collaborators":66,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":25,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":25,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":92,"overallStatus":97,"whyStopped":25,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Cornell University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Calcium-Rich Food","EXPERIMENTAL","Participants assigned to this arm will consume one calcium-rich food providing 500 mg of calcium from milk-derived minerals once daily for four weeks. The product will be supplied in unbranded packaging. Participants will complete baseline and weekly questionnaires assessing adherence, gastrointestinal tolerability, treatment satisfaction, and safety.",[13],"Other: 500 mg calcium from milk-derived minerals",{"label":15,"type":16,"description":17,"interventionNames":18},"Calcium Carbonate Supplement","ACTIVE_COMPARATOR","Participants assigned to this arm will consume one 500 mg calcium carbonate supplement once daily with food for four weeks. Participants will complete baseline and weekly questionnaires assessing adherence, gastrointestinal tolerability, treatment satisfaction, and safety.",[19],"Dietary Supplement: Calcium Carbonate 500 MG",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"500 mg calcium from milk-derived minerals","A calcium-rich food providing 500 mg of calcium from milk-derived minerals, consumed once daily for four weeks. The product also contains dates, milk protein concentrate, almonds, vitamin D from mushrooms, and white button mushrooms. Participants consume one serving daily with or without food. The product is supplied in unbranded packaging.",[9],null,{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":25},"DIETARY_SUPPLEMENT","Calcium Carbonate 500 MG","A commercially available calcium carbonate supplement providing 500 mg calcium, taken once daily with food for four weeks.",[15],[32],{"name":33,"affiliation":34,"role":35},"Jeff Zhu","Weill Medical College of Cornell University","STUDY_DIRECTOR",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":25,"email":41},"Adrienne Bitar, PhD","CONTACT","4154255198","arj67@cornell.edu",{"name":43,"role":39,"phone":44,"phoneExt":25,"email":45},"Jennifer Han, PharmD","925-389-8080","jhan@seennutrition.com",[47],{"facility":48,"status":25,"city":49,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"Clinical and Translational Science Center, Weill Cornell Medical College","New York","10065","United States","US",{"type":54,"coordinates":55},"Point",[56,57],-74.00597,40.71427,{"lat":57,"lon":56},[60],{"name":33,"role":39,"phone":25,"phoneExt":25,"email":61},"jez2003@med.cornell.edu",{"type":63,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Adrienne Bitar","Principal Investigator",[67],{"name":34,"class":6},"100651601","calcium-rich-food-versus-calcium-carbonate-for-bone-health-100651601",false,"NCT07763509","Calcium-Rich Food Versus Calcium Carbonate for Bone Health","Evaluating Adherence, Tolerability, and Safety of a Novel Oral Dietary Calcium Chew vs. Calcium Carbonate in Women 40-90: A Real-Life, Prospective, Randomized Controlled Trial","Inclusion Criteria Female at birth, 40 to 90 years of age Family history of osteoporosis or history of fracture Willing and able to provide written informed consent Willing to comply with all study procedures Willing to refrain from making major dietary changes during the 4-week study No known allergy or intolerance to any study product ingredients Exclusion Criteria Medical condition that would interfere with study participation or adherence (including selected oncologic or psychiatric disorders) Known severe allergic reaction requiring an epinephrine auto-injector Pregnant, breastfeeding, or planning to become pregnant during the study Invasive medical procedure within the previous 3 months or planned during the study period Current participation in another research study or planning to participate during the study period Difficulty swallowing (dysphagia)\n\n\\-",true,"FEMALE","40 Years","90 Years",{"count":80,"type":81},217,"ESTIMATED","INTERVENTIONAL",[84],"NA","This study will compare adherence, tolerability, safety, and treatment satisfaction between a calcium-rich food and a traditional calcium carbonate supplement in women ages 40 to 90 who are at increased risk for osteoporosis. Participants will be randomly assigned to receive either a calcium-rich food providing 500 mg of calcium from milk-derived minerals or a 500 mg calcium carbonate supplement once daily for four weeks. Participants will complete brief weekly questionnaires assessing supplement use, gastrointestinal symptoms, and treatment satisfaction. The goal of the study is to determine whether the form in which calcium is consumed influences adherence and participant experience. No blood draws, imaging studies, or other invasive procedures are involved",[87,88,89,90,91],"Osteopenia","Osteoporosis","Bone Health in Perimenopausal Women","Menopause Related Conditions","Fracture Healing",[88,93,94,95,96],"osteopenia","bone health","menopause","Fractures","NOT_YET_RECRUITING","2026-08-10",{"date":100,"type":101},"2026-08-13","ACTUAL",{"date":103,"type":81},"2026-09-01",{"date":105,"type":81},"2027-10-01",{"name":5,"class":6},1]