[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100659167":3},{"organization":4,"outcomesModule":7,"designInfo":30,"detailedDescription":33,"studyPopulation":34,"armGroups":35,"interventions":29,"overallOfficials":39,"centralContacts":44,"locations":29,"responsibleParty":50,"collaborators":29,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":29,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":29,"studyType":67,"phases":29,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":79,"whyStopped":29,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":29},{"fullName":5,"class":6},"Assiut University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":29},[9],{"measure":10,"description":11,"timeFrame":12},"Mean left ventricular mass index","Mean left ventricular mass index measured by echocardiography in g\u002Fm².","Baseline",[14,17,20,23,26],{"measure":15,"description":16,"timeFrame":12},"Mean P-wave dispersion","Mean P-wave dispersion measured on 12-lead electrocardiogram in milliseconds.",{"measure":18,"description":19,"timeFrame":12},"Mean corrected QT interval","Mean corrected QT interval (QTc) measured on 12-lead electrocardiogram in milliseconds.",{"measure":21,"description":22,"timeFrame":12},"Mean E\u002FA ratio","Mean early to late diastolic filling velocity ratio (E\u002FA ratio) measured by pulsed-wave Doppler echocardiography.",{"measure":24,"description":25,"timeFrame":12},"Mean left ventricular wall thickness","Mean left ventricular wall thickness measured by echocardiography in millimeters.",{"measure":27,"description":28,"timeFrame":12},"Mean body mass index","Mean body mass index in kg\u002Fm².",null,{"allocation":29,"interventionModel":29,"interventionModelDescription":29,"primaryPurpose":29,"observationalModel":31,"timePerspective":32,"maskingInfo":29},"CASE_ONLY","CROSS_SECTIONAL","Childhood obesity is associated with early cardiovascular structural and electrophysiological changes. This observational study will evaluate left ventricular structure and function by echocardiography and electrocardiographic parameters including P-wave duration and dispersion in children and adolescents with obesity aged 1 to 18 years.","Children and adolescents aged 1 to 18 years with obesity (BMI ≥95th percentile for age and sex) attending Assiut University Children's Hospital.",[36],{"label":37,"type":29,"description":38,"interventionNames":29},"Obese Children","Children and adolescents aged 1 to 18 years with body mass index ≥95th percentile for age and sex attending Assiut University Children's Hospital.",[40],{"name":41,"affiliation":42,"role":43},"Faisel E Ahmed, prof","Pediatrics Department, Assiut University Hospitals","STUDY_CHAIR",[45],{"name":46,"role":47,"phone":48,"phoneExt":29,"email":49},"Mohamed A Mohamed, Resident","CONTACT","+20 10 30046583","mohamedmnr949@gmail.com",{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"PRINCIPAL_INVESTIGATOR","Mohamed Ahmed Mohamed Hussein","Resident Physician, Department of Pediatrics","100659167","cardiovascular-alterations-in-obese-children-100659167",false,"NCT07859657","Cardiovascular Alterations in Obese Children","Cardiovascular Structural and Electrophysiological Alterations in Obese Children Attending Assiut University Children's Hospital","Inclusion Criteria:\n\n* \\- Age 1 to 18 years\n* Body mass index ≥95th percentile for age and sex\n* No previously diagnosed structural heart disease\n* No known primary cardiac rhythm or conduction disorder\n* Written informed consent from parent or legal guardian\n\nExclusion Criteria:\n\n* \\- Known structural heart disease\n* Known cardiac arrhythmia or conduction abnormality\n* Diabetes mellitus\n* Hypertension requiring treatment\n* Hypothyroidism or other endocrine disorders affecting cardiac function\n* Chronic renal, hepatic, respiratory, or systemic disease\n* Pulmonary hypertension\n* Obstructive sleep apnea\n* Medications known to affect cardiac rhythm or function\n* Electrolyte abnormalities\n* Acute significant illness at the time of assessment","ALL","1 Year","18 Years",{"count":65,"type":66},150,"ESTIMATED","OBSERVATIONAL","This cross-sectional study aims to assess cardiovascular structural and electrophysiological alterations in obese children attending Assiut University Children's Hospital.",[70],"Pediatric Obesity",[72,73,74,75,76,77,78],"Obesity","Echocardiography","Electrocardiography","Left ventricular mass","P-wave dispersion","Assiut","Children","NOT_YET_RECRUITING","2026-10-01",{"date":82,"type":83},"2026-10-06","ACTUAL",{"date":85,"type":66},"2026-10-02",{"date":87,"type":66},"2028-03-01",{"name":5,"class":6}]