[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100654092":3},{"organization":4,"outcomesModule":7,"designInfo":19,"detailedDescription":22,"studyPopulation":23,"armGroups":24,"interventions":18,"overallOfficials":18,"centralContacts":28,"locations":18,"responsibleParty":34,"collaborators":18,"id":38,"slug":39,"hasResults":40,"nctId":41,"briefTitle":42,"officialTitle":43,"acronym":44,"eligibilityCriteria":45,"healthyVolunteers":40,"sex":46,"minAge":47,"maxAge":48,"enrollmentInfo":49,"targetDuration":18,"studyType":52,"phases":18,"briefSummary":53,"conditions":54,"keywords":56,"overallStatus":58,"whyStopped":18,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":18},{"fullName":5,"class":6},"Assiut University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":18},[9],{"measure":10,"description":11,"timeFrame":12},"number of cases with NICU admission","number of neonates admitted in neonatal care unit within 24 hours after delivery","6 weeks",[14],{"measure":15,"description":16,"timeFrame":17},"weight of birth","birth weight in grams after delivery","1 day",null,{"allocation":18,"interventionModel":18,"interventionModelDescription":18,"primaryPurpose":18,"observationalModel":20,"timePerspective":21,"maskingInfo":18},"COHORT","PROSPECTIVE","A prospective cohort study will be conducted to compare the predictive accuracy of the cerebroplacental ratio (CPR) and the amniotic-umbilical-to-cerebral ratio (AUCR) for composite adverse perinatal outcomes among women with hypertensive disorders of pregnancy.","pregnant women with hypertensive disorder",[25],{"label":26,"type":18,"description":27,"interventionNames":18},"obstetric doppler indices in hypertensive disorder with pregnancy","A prospective cohort study will be conducted to compare the predictive accuracy of the cerebroplacental ratio (CPR) and the amniotic-umbilical-to-cerebral ratio (AUCR) for composite adverse perinatal outcomes among women with hypertensive disorders of pregnancy.Fetal ultrasonographic measurements, including deepest vertical pocket (DVP) for amniotic fluid, and Doppler parameters including UtA systolic\u002Fdiastolic (S\u002FD) and pulsatility index (PI), MCA S\u002FD and PI, and UA S\u002FD and PI, will conducted following fetal biometry EFW was computed. CPR was determined using the ratio of MCA PI to UA PI.8 UCR will calculated as the inverse of CPR, the ratio of UA PI to MCA PI.11 CPUR was determined using the ratio of CPR to UtA PI.13 The DVP method will implemented to estimate the amniotic fluid volume.19 The AUCR will calculated as the ratio of DVP to UA PI\u002FMCA PI",[29],{"name":30,"role":31,"phone":32,"phoneExt":18,"email":33},"Abdelrahman Mahmoud, MD","CONTACT","08802089519","abdelrahman_mahmoud2@aun.edu.eg",{"type":35,"investigatorFullName":36,"investigatorTitle":37,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Abdelrahman Mahmoud Mohammed","lecturer of obstetrics and gynecology, MD","100654092","cerebroplacental-ratio-cpr-and-amniotic-umbilical-to-cerebral-ratio-aucr-in-in-women-with-hypertensive-disorders-of-pregnancy-100654092",false,"NCT07795320","Cerebroplacental Ratio (CPR) and Amniotic-Umbilical-to-Cerebral Ratio (AUCR), in in Women With Hypertensive Disorders of Pregnancy.","Comparison Between Cerebroplacental Ratio (CPR) and Amniotic-Umbilical-to-Cerebral Ratio (AUCR), in Predicting of Adverse Perinatal Outcome in Women With Hypertensive Disorders of Pregnancy.","CPR_AUCR2026","Inclusion Criteria:\n\n* Women aged 18-40 years, inclusive.\n* Singleton viable pregnancy.\n* Gestational age ≥32 weeks.\n* Pregnancy complicated by a hypertensive disorder.\n* Women who provide written informed consent.\n\nExclusion Criteria:\n\n* Multiple gestation.\n* Fetuses with known chromosomal or major congenital anomalies.\n* Maternal diseases likely to independently affect fetal circulation or perinatal outcome, such as significant cardiac disease or other major systemic diseases.\n* Inability to complete the required follow-up.","FEMALE","18 Years","40 Years",{"count":50,"type":51},130,"ESTIMATED","OBSERVATIONAL","The primary aim of this study is to evaluate the predictive value of the Amniotic-Umbilical-to-Cerebral Ratio (AUCR) in predicting composite adverse perinatal outcomes in women with hypertensive disorders of pregnancy and to compare its predictive performance with the traditional Cerebroplacental Ratio (CPR)",[55],"Hypertension Disorders in Pregnancy",[57],"Hypertension With Pregnancy","NOT_YET_RECRUITING","2026-08-27",{"date":61,"type":62},"2026-08-31","ACTUAL",{"date":64,"type":51},"2026-11-01",{"date":66,"type":51},"2028-04-01",{"name":5,"class":6}]