[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100659083":3},{"organization":4,"outcomesModule":7,"designInfo":89,"detailedDescription":88,"studyPopulation":92,"armGroups":93,"interventions":103,"overallOfficials":109,"centralContacts":114,"locations":119,"responsibleParty":134,"collaborators":88,"id":137,"slug":138,"hasResults":139,"nctId":140,"briefTitle":141,"officialTitle":142,"acronym":88,"eligibilityCriteria":143,"healthyVolunteers":139,"sex":144,"minAge":145,"maxAge":88,"enrollmentInfo":146,"targetDuration":88,"studyType":149,"phases":88,"briefSummary":150,"conditions":151,"keywords":88,"overallStatus":122,"whyStopped":88,"lastUpdateSubmitDate":153,"lastUpdatePostDateStruct":154,"startDateStruct":157,"completionDateStruct":159,"leadSponsor":161,"locationsCount":162},{"fullName":5,"class":6},"Bagcilar Training and Research Hospital","OTHER_GOV",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":88},[9],{"measure":10,"description":11,"timeFrame":12},"Umbilical artery pH","Umbilical arterial pH measured after delivery and cord clamping.","Immediately after delivery",[14,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,67,71,75,78,82,85],{"measure":15,"description":16,"timeFrame":17},"Maternal venous pH","Maternal venous pH measured immediately before anesthesia induction.","Immediately before anesthesia induction",{"measure":19,"description":20,"timeFrame":12},"Umbilical artery pCO2","Umbilical arterial pCO2 measured after delivery and cord clamping.",{"measure":22,"description":23,"timeFrame":12},"Umbilical artery pO2","Umbilical arterial pO2 measured after delivery and cord clamping.",{"measure":25,"description":26,"timeFrame":17},"Maternal venous pCO2","Maternal venous pCO2 measured immediately before anesthesia induction",{"measure":28,"description":29,"timeFrame":17},"Maternal venous pO2","Maternal venous pO2 measured immediately before anesthesia induction",{"measure":31,"description":32,"timeFrame":12},"Umbilical artery HCO3","Umbilical arterial bicarbonate measured after delivery and cord clamping.",{"measure":34,"description":35,"timeFrame":17},"Maternal venous HCO3","Maternal venous bicarbonate measured immediately before anesthesia induction",{"measure":37,"description":38,"timeFrame":12},"Umbilical artery BE","Umbilical arterial base excess measured after delivery and cord clamping",{"measure":40,"description":41,"timeFrame":17},"Maternal venous BE","Maternal venous base excess measured immediately before anesthesia induction",{"measure":43,"description":44,"timeFrame":12},"Umbilical artery lactate","Umbilical arterial lactate measured after delivery and cord clamping",{"measure":46,"description":47,"timeFrame":17},"Maternal venous lactate","Maternal venous lactate measured immediately before anesthesia induction",{"measure":49,"description":50,"timeFrame":12},"Umbilical artery FCOHb","Fetal carboxyhemoglobin measured in umbilical arterial blood after delivery and cord clamping",{"measure":52,"description":53,"timeFrame":17},"Maternal venous FCOHb","Maternal carboxyhemoglobin measured in venous blood immediately before anesthesia induction",{"measure":55,"description":56,"timeFrame":12},"Maternal-fetal pH gradient (ΔpH)","Difference between maternal venous pH and umbilical arterial pH",{"measure":58,"description":59,"timeFrame":12},"Maternal-fetal pCO2 gradient (ΔpCO2)","Difference between maternal venous pCO2 and umbilical arterial pCO2",{"measure":61,"description":62,"timeFrame":12},"Maternal-fetal lactate gradient (Δlactate)","Difference between maternal venous lactate and umbilical arterial lactate",{"measure":64,"description":65,"timeFrame":66},"Apgar score at 1 minute","Apgar score assessed 1 minute after birth using the Apgar score (range, 0-10), with higher scores indicating better neonatal condition.","1 minute after birth",{"measure":68,"description":69,"timeFrame":70},"Apgar score at 5 minutes","Apgar score assessed 5 minutes after birth using the Apgar score (range, 0-10), with higher scores indicating better neonatal condition.","5 minutes after birth",{"measure":72,"description":73,"timeFrame":74},"Neonatal intensive care unit admission","Requirement for admission to the neonatal intensive care unit after birth","During the immediate neonatal period",{"measure":76,"description":77,"timeFrame":74},"Neonatal intubation","Requirement for endotracheal intubation after birth",{"measure":79,"description":80,"timeFrame":81},"Maternal hypotension requiring treatment","Occurrence of maternal hypotension requiring pharmacologic treatment during cesarean delivery","From anesthesia induction until the end of surgery",{"measure":83,"description":84,"timeFrame":81},"Maternal vasopressor requirement","Requirement for vasopressor administration for management of maternal hypotension during cesarean delivery",{"measure":86,"description":87,"timeFrame":12},"Smoking exposure and fetal FCOHb","Association between maternal smoking exposure status and fetal carboxyhemoglobin level measured in umbilical arterial blood",null,{"allocation":88,"interventionModel":88,"interventionModelDescription":88,"primaryPurpose":88,"observationalModel":90,"timePerspective":91,"maskingInfo":88},"COHORT","PROSPECTIVE","Pregnant women undergoing cesarean delivery at the Obstetrics and Gynecology Clinic of Bagcilar Training and Research Hospital. The study is a prospective observational cohort comparing maternal and fetal blood gas parameters and fetal carboxyhemoglobin levels according to the observed anesthesia technique (spinal or general anesthesia).",[94,99],{"label":95,"type":88,"description":96,"interventionNames":97},"Spinal Anesthesia","Participants undergoing cesarean delivery who receive spinal anesthesia as the anesthesia technique.",[98],"Other: Anesthesia Technique",{"label":100,"type":88,"description":101,"interventionNames":102},"General Anesthesia","Participants undergoing cesarean delivery who receive general anesthesia as the anesthesia technique.",[98],[104],{"type":105,"name":106,"description":107,"armGroupLabels":108,"otherNames":88},"OTHER","Anesthesia Technique","Observed anesthesia technique in women undergoing cesarean delivery. Participants received either spinal anesthesia or general anesthesia as part of routine clinical care; the anesthesia technique was not assigned by the study.",[100,95],[110],{"name":111,"affiliation":112,"role":113},"Ali KAHVECİOĞLU, MD","University of Health Sciences, Bağcılar Training and Research Hospital","PRINCIPAL_INVESTIGATOR",[115],{"name":111,"role":116,"phone":117,"phoneExt":88,"email":118},"CONTACT","+90 5549134317","ali.kahveci92@gmail.com",[120],{"facility":121,"status":122,"city":123,"state":123,"zip":124,"country":125,"countryCode":88,"cosmosGeoPoint":126,"geoPoint":131,"contacts":132},"Bağcılar Training and Research Hospital","RECRUITING","Istanbul","59050","Turkey (Türkiye)",{"type":127,"coordinates":128},"Point",[129,130],28.94966,41.01384,{"lat":130,"lon":129},[133],{"name":111,"role":116,"phone":117,"phoneExt":88,"email":118},{"type":113,"investigatorFullName":135,"investigatorTitle":136,"investigatorAffiliation":5,"oldNameTitle":88,"oldOrganization":88},"ali kahvecioğlu","DİRECTOR","100659083","cesarean-anesthesia-blood-gas-100659083",false,"NCT07861633","Cesarean Anesthesia Blood Gas","Effects of Spinal and General Anesthesia Techniques on Maternal-Fetal Blood Gas Gradients and Fetal Carboxyhemoglobin Levels in Cesarean Delivery: A Prospective Observational Cohort Study","Inclusion Criteria:\n\n* Adult women undergoing cesarean delivery at the study center.\n* Patients receiving spinal or general anesthesia for cesarean delivery.\n\nExclusion Criteria:\n\n* Patients who are not eligible for participation according to the study protocol.\n* Patients in whom spinal anesthesia is converted to general anesthesia because of inadequate spinal block and pain during surgery.","FEMALE","18 Years",{"count":147,"type":148},134,"ESTIMATED","OBSERVATIONAL","This prospective observational cohort study will evaluate maternal and fetal blood gas parameters in women undergoing cesarean delivery under spinal or general anesthesia. Maternal venous blood samples will be obtained immediately before anesthesia induction, and umbilical arterial blood samples will be obtained after delivery and cord clamping. Blood gas parameters, including pH, pCO2, pO2, bicarbonate, base excess, lactate, and fetal carboxyhemoglobin levels, will be compared between the spinal and general anesthesia groups. The study will also evaluate maternal-fetal blood gas gradients, Apgar scores, neonatal intensive care requirements, and the relationship between smoking exposure and fetal carboxyhemoglobin levels.",[152],"Cesarean Delivery","2026-10-06",{"date":155,"type":156},"2026-10-08","ACTUAL",{"date":158,"type":156},"2026-10-01",{"date":160,"type":148},"2026-12-31",{"name":5,"class":6},1]