[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100658906":3},{"organization":4,"outcomesModule":7,"designInfo":33,"detailedDescription":36,"studyPopulation":37,"armGroups":38,"interventions":32,"overallOfficials":42,"centralContacts":47,"locations":32,"responsibleParty":53,"collaborators":32,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":32,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":32,"maxAge":65,"enrollmentInfo":66,"targetDuration":32,"studyType":69,"phases":32,"briefSummary":70,"conditions":71,"keywords":74,"overallStatus":80,"whyStopped":32,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":32},{"fullName":5,"class":6},"Assiut University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":32},[9],{"measure":10,"description":11,"timeFrame":12},"Sensitivity of chest ultrasound for diagnosis of respiratory distress syndrome","Sensitivity of chest ultrasound for the diagnosis of respiratory distress syndrome in preterm neonates, using chest X-ray as the reference standard.","Baseline",[14,17,20,23,26,29],{"measure":15,"description":16,"timeFrame":12},"Specificity of chest ultrasound","Specificity of chest ultrasound for the diagnosis of respiratory distress syndrome.",{"measure":18,"description":19,"timeFrame":12},"Positive predictive value of chest ultrasound","Positive predictive value of chest ultrasound for the diagnosis of respiratory distress syndrome.",{"measure":21,"description":22,"timeFrame":12},"Negative predictive value of chest ultrasound","Negative predictive value of chest ultrasound for the diagnosis of respiratory distress syndrome.",{"measure":24,"description":25,"timeFrame":12},"Overall diagnostic accuracy of chest ultrasound","Overall diagnostic accuracy of chest ultrasound for diagnosis of respiratory distress syndrome calculated as (true positives + true negatives) divided by total cases, using chest X-ray as reference standard.",{"measure":27,"description":28,"timeFrame":12},"Proportion of neonates with white lung appearance on ultrasound","Proportion of preterm neonates showing white lung appearance on chest ultrasound.",{"measure":30,"description":31,"timeFrame":12},"Proportion of neonates with abnormal pleural line on ultrasound","Proportion of preterm neonates showing abnormal or irregular pleural line on chest ultrasound.",null,{"allocation":32,"interventionModel":32,"interventionModelDescription":32,"primaryPurpose":32,"observationalModel":34,"timePerspective":35,"maskingInfo":32},"CASE_ONLY","CROSS_SECTIONAL","Neonatal respiratory distress syndrome is a major cause of morbidity in preterm infants. Chest X-ray is traditionally used for diagnosis but involves ionizing radiation. Lung ultrasound is a bedside, radiation-free alternative.\n\nThis observational study will include preterm neonates (≤35 weeks of gestation) presenting with clinical respiratory distress within the first 24 hours of life. Chest ultrasound and chest X-ray findings will be compared to assess diagnostic performance.","Preterm neonates (≤35 weeks of gestation) with clinical respiratory distress presenting at Assiut University Children's Hospital.",[39],{"label":40,"type":32,"description":41,"interventionNames":32},"Single cohort: Preterm Neonates with Respiratory Distress","Preterm neonates (≤35 weeks of gestation) presenting with clinical and radiographic signs of respiratory distress syndrome within the first 24 hours of life who will undergo both chest ultrasound and chest X-ray.",[43],{"name":44,"affiliation":45,"role":46},"Mohamed A fathy, prof","Pediatrics Department, Assiut University Hospitals","STUDY_CHAIR",[48],{"name":49,"role":50,"phone":51,"phoneExt":32,"email":52},"Mariam m Elisha, Resident","CONTACT","+20 12 08409555","mmariammousa@gmail.com",{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"PRINCIPAL_INVESTIGATOR","Mariam Mousa Alisha","Resident Physician, Department of Pediatrics","100658906","chest-ultrasound-versus-chest-x-ray-in-neonatal-respiratory-distress-syndrome-100658906",false,"NCT07857304","Chest Ultrasound Versus Chest X-ray in Neonatal Respiratory Distress Syndrome","Chest Ultrasound in the Diagnosis of Respiratory Distress Syndrome Versus Chest X-ray","Inclusion Criteria:\n\n* \\- Preterm neonates ≤35 weeks of gestation\n* Clinical signs of respiratory distress within the first 24 hours of life\n* Radiographic data suggestive of respiratory distress syndrome\n* Written informed consent from parents or legal guardians\n\nExclusion Criteria:\n\n* \\- Major congenital anomalies of the respiratory system","ALL","24 Hours",{"count":67,"type":68},82,"ESTIMATED","OBSERVATIONAL","This cross-sectional study aims to evaluate the diagnostic accuracy of chest ultrasound in the diagnosis of respiratory distress syndrome among preterm neonates in comparison with chest X-ray.",[72,73],"Respiratory Distress Syndrome, Newborn","Neonatal Respiratory Distress",[75,76,77,78,79],"Lung ultrasound","Respiratory distress syndrome","Chest X-ray","Preterm neonates","Assiut","NOT_YET_RECRUITING","2026-10-01",{"date":83,"type":84},"2026-10-05","ACTUAL",{"date":86,"type":68},"2026-09-28",{"date":88,"type":68},"2028-02-25",{"name":5,"class":6}]