[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100655043":3},{"organization":4,"outcomesModule":7,"designInfo":25,"detailedDescription":28,"studyPopulation":29,"armGroups":30,"interventions":24,"overallOfficials":34,"centralContacts":39,"locations":24,"responsibleParty":45,"collaborators":24,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":24,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":62,"studyType":63,"phases":24,"briefSummary":64,"conditions":65,"keywords":69,"overallStatus":75,"whyStopped":24,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":81,"leadSponsor":83,"locationsCount":24},{"fullName":5,"class":6},"Assiut University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":24},[9],{"measure":10,"description":11,"timeFrame":12},"Diagnostic accuracy of lung ultrasound versus chest X-ray","Sensitivity, specificity, positive predictive value, and negative predictive value of lung ultrasound compared with chest X-ray for the diagnosis of neonatal pneumonia, using a composite clinical reference standard.","At the time of clinical suspicion of pneumonia (Baseline)",[14,18,21],{"measure":15,"description":16,"timeFrame":17},"Comparison of radiographic and sonographic findings","Description and comparison of chest X-ray findings (opacities, air bronchograms, pleural effusion) and lung ultrasound findings (subpleural consolidation, dynamic air bronchograms, B-lines, pleural line abnormalities).","Baseline",{"measure":19,"description":20,"timeFrame":17},"Correlation with clinical severity","Correlation between chest X-ray grading and lung ultrasound scores with clinical severity indices of neonatal respiratory distress (oxygenation index, FiO2 requirement, respiratory support level).",{"measure":22,"description":23,"timeFrame":17},"Risk factors associated with neonatal pneumonia","Antenatal, perinatal, and postnatal risk factors associated with the diagnosis of neonatal pneumonia.",null,{"allocation":24,"interventionModel":24,"interventionModelDescription":24,"primaryPurpose":24,"observationalModel":26,"timePerspective":27,"maskingInfo":24},"COHORT","PROSPECTIVE","Neonatal pneumonia is a leading cause of respiratory morbidity and mortality in the neonatal period. Chest X-ray has traditionally been the reference imaging modality, but it involves ionizing radiation and has moderate sensitivity. Lung ultrasound is a radiation-free, bedside alternative that has shown promising diagnostic performance.\n\nThis prospective study will include term and preterm neonates admitted to the NICU with clinical suspicion of pneumonia within the first 28 days of life. All participants will undergo both portable chest X-ray and standardized lung ultrasound performed by trained examiners blinded to each other's findings. Diagnostic accuracy of both modalities will be compared against a composite clinical reference standard.","Term and preterm neonates admitted to the Neonatal Intensive Care Unit of Assiut University Children's Hospital with clinical diagnosis of pneumonia within the first 28 days of life.",[31],{"label":32,"type":24,"description":33,"interventionNames":24},"Single cohort: Neonates with clinical suspicion of pneumonia","Term and preterm neonates admitted to the NICU with clinical signs suggestive of pneumonia who will undergo both chest X-ray and lung ultrasound for diagnostic comparison.",[35],{"name":36,"affiliation":37,"role":38},"Khaled A Sanousy, prof","Pediatrics Department, Assiut University Hospitals","STUDY_CHAIR",[40],{"name":41,"role":42,"phone":43,"phoneExt":24,"email":44},"Rana H Rayan, Resident","CONTACT","+20 10 69579624","Rana.18313199@med.aun.edu.eg",{"type":46,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Rana Hosny Rayan Manaa","Resident Physician","100655043","chest-x-ray-versus-lung-ultrasound-in-neonatal-pneumonia-100655043",false,"NCT07807514","Chest X-Ray Versus Lung Ultrasound in Neonatal Pneumonia","Chest X-Ray Versus Chest Ultrasound in Diagnosis of Neonatal Pneumonia","Inclusion Criteria:\n\n* \\- Neonates (term and preterm) admitted to the NICU\n* Clinical diagnosis of pneumonia within the first 28 days of life\n* Written informed consent from parents or legal guardians\n\nExclusion Criteria:\n\n* \\- Major congenital pulmonary or cardiac structural malformations that would confound imaging interpretation\n* Lethal congenital anomalies or chromosomal abnormalities incompatible with survival","ALL","1 Minute","28 Days",{"count":60,"type":61},100,"ESTIMATED","1 Day","OBSERVATIONAL","This prospective observational study aims to compare the diagnostic accuracy of chest X-ray versus lung ultrasound in the diagnosis of neonatal pneumonia among neonates admitted to the Neonatal Intensive Care Unit of Assiut University Children's Hospital.",[66,67,68],"Neonatal Pneumonia","Respiratory Distress Syndrome","Pneumonia Neonatal",[70,71,72,73,74],"Point-of-care ultrasound","Diagnostic accuracy","Chest X-ray","Lung ultrasound","Neonatal pneumonia","NOT_YET_RECRUITING","2026-09-02",{"date":78,"type":79},"2026-09-08","ACTUAL",{"date":76,"type":61},{"date":82,"type":61},"2028-07-20",{"name":5,"class":6}]