[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100513960":3},{"organization":4,"armGroups":7,"interventions":35,"overallOfficials":67,"centralContacts":34,"locations":71,"responsibleParty":91,"collaborators":34,"id":93,"slug":94,"hasResults":95,"nctId":96,"briefTitle":97,"officialTitle":98,"acronym":99,"eligibilityCriteria":100,"healthyVolunteers":101,"sex":102,"minAge":103,"maxAge":104,"enrollmentInfo":105,"targetDuration":34,"studyType":108,"phases":109,"briefSummary":111,"conditions":112,"keywords":34,"overallStatus":73,"whyStopped":34,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":123},{"fullName":5,"class":6},"University of Texas at Austin","OTHER",[8,17,22,30],{"label":9,"type":10,"description":11,"interventionNames":12},"Acute Exercise Moderate first","EXPERIMENTAL","Day 1 Assessments, Day 8 Moderate Intensity Exercise (followed by symptom measures and neuropsychological tests), Day 15 Light Intensity Exercise (symptom measures and neuropsychological tests)",[13,14,15,16],"Behavioral: Moderate Intensity Exercise (one day)","Behavioral: Placebo - Light Intensity Exercise (one day)","Other: Day 1 Assessments","Other: Symptom Measures and Neuropsychological Tests",{"label":18,"type":19,"description":20,"interventionNames":21},"Acute Exercise Light first","ACTIVE_COMPARATOR","Control Day 1 Assessments (symptom measures, neuropsychological tests, and cognitive complaints interview), Day 8 Light Intensity Exercise (followed by symptom measures and neuropsychological tests), Day 15 Moderate Intensity Exercise (symptom measures and neuropsychological tests)",[13,14,15,16],{"label":23,"type":10,"description":24,"interventionNames":25},"Chronic Exercise Moderate","9-weeks Moderate Intensity Exercise Day 36 (at 3 weeks) Assessments Day 57 (at 6 weeks) Assessments Day 78 (at 9 weeks) Assessments",[26,27,28,29],"Behavioral: Moderate Intensity Exercise (9 wks)","Other: Day 36 Assessments","Other: Day 57 Assessments","Other: Day 78 Assessments",{"label":31,"type":32,"description":33,"interventionNames":34},"Activity as Usual","NO_INTERVENTION","9-week activity as usual Day 36 (at 3 weeks) Assessments Day 57 (at 6 weeks) Assessments Day 78 (at 9 weeks) Assessments",null,[36,41,45,49,53,57,61,64],{"type":37,"name":38,"description":39,"armGroupLabels":40,"otherNames":34},"BEHAVIORAL","Moderate Intensity Exercise (one day)","Participants will engage in 40 minutes of cycling at 70-75% maximum heart rate (MHR).",[18,9],{"type":37,"name":42,"description":43,"armGroupLabels":44,"otherNames":34},"Placebo - Light Intensity Exercise (one day)","Control participants will engage in 40 minutes cycling at 40-50% maximum heart rate (MHR).",[18,9],{"type":37,"name":46,"description":47,"armGroupLabels":48,"otherNames":34},"Moderate Intensity Exercise (9 wks)","Participants will be asked to engage in moderate-intensity activity four days each week, 40 minutes each time, and will wear an activity monitoring device to assess their fidelity to the intervention.",[23],{"type":6,"name":50,"description":51,"armGroupLabels":52,"otherNames":34},"Day 1 Assessments","Cognitive complaints interview, Center for Epidemiological Studies Depression Scale Revised (CESD-R), Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5), Life Events Checklist (LEC-5), and neuropsychological testing: approximately 1.50 hours",[18,9],{"type":6,"name":54,"description":55,"armGroupLabels":56,"otherNames":34},"Symptom Measures and Neuropsychological Tests","Center for Epidemiological Studies Depression Scale Revised (CESD-R), Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5), and neuropsychological testing: approximately 1.25 hours",[18,9],{"type":6,"name":58,"description":59,"armGroupLabels":60,"otherNames":34},"Day 36 Assessments","Activity monitoring device charged and data downloaded, questions regarding fidelity to activity as usual or moderate-intensity exercise and any difficulties, Cognitive complaints interview, Center for Epidemiological Studies Depression Scale Revised (CESD-R), Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5), neuropsychological testing, and activity monitoring device returned to participant: approximately 2.00 hours",[23],{"type":6,"name":62,"description":59,"armGroupLabels":63,"otherNames":34},"Day 57 Assessments",[23],{"type":6,"name":65,"description":59,"armGroupLabels":66,"otherNames":34},"Day 78 Assessments",[23],[68],{"name":69,"affiliation":5,"role":70},"Erin Logue, PhD","PRINCIPAL_INVESTIGATOR",[72],{"facility":5,"status":73,"city":74,"state":75,"zip":76,"country":77,"countryCode":78,"cosmosGeoPoint":79,"geoPoint":84,"contacts":85},"RECRUITING","Austin","Texas","78712","United States","US",{"type":80,"coordinates":81},"Point",[82,83],-97.74306,30.26715,{"lat":83,"lon":82},[86],{"name":87,"role":88,"phone":89,"phoneExt":34,"email":90},"Erin Logue","CONTACT","512-954-5510","erin.logue@austin.utexas.edu",{"type":70,"investigatorFullName":87,"investigatorTitle":92,"investigatorAffiliation":5,"oldNameTitle":34,"oldOrganization":34},"assistant professor","100513960","childhood-trauma-exercise-and-cognition-100513960",false,"NCT05972265","Childhood Trauma, Exercise, and Cognition","Exercise and Cognition in Middle-Aged Adults With Histories of Childhood Trauma and Cognitive Complaints","CTEC","Inclusion Criteria:\n\n* between 40 and 60 years of age\n* history of child abuse or neglect\n* have a complaint about memory, attention, or executive function\n* native or fluent English speaker\n* normal or corrected to normal vision and hearing\n* medically healthy\n\nExclusion Criteria:\n\n* Score indicating a history of moderate-intensity activity, hard-intensity activity, or very-hard intensity activity on the Stanford Brief Activity Survey\n* current excessive alcohol or other substance use\n* eating disorder, bipolar disorder, schizophrenia spectrum disorders, or those judged to be an immediate suicide risk based on having an active plan with intent\n* autism spectrum disorder, attention-deficit\u002Fhyperactivity disorder (ADHD), or other neurodevelopmental disorder\n* neurocognitive disorder, or illnesses or history of neurological events known to cause neurocognitive disorders (e.g., traumatic brain injury, status epilepticus, stroke)\n* reported chest pain or dizziness during exercise; any endorsed and not controlled medical condition that could make exercise contraindicated, including hypertension; heart disease; heart failure; hear rhythm disorders; heart valve disease; metabolic conditions; chronic obstructive pulmonary disease; pulmonary hypertension; cystic fibrosis; asthma; and bone, joint, or soft tissue problems\n* pregnancy, major medical disorders such as cancer, or any other condition believed to put a participant at risk",true,"ALL","40 Years","60 Years",{"count":106,"type":107},34,"ESTIMATED","INTERVENTIONAL",[110],"NA","This study aims to identify and compare the effects of acute and chronic exercise interventions on cognition in middle-aged adults with cognitive complaints and a history of abuse or neglect in childhood. Each participant will be enrolled in the study for up to 78 days, in five parts following verification that the participant meets criteria to be included in the study: 1) initial assessment; 2) first acute exercise condition in lab, symptom measures, and neuropsychological testing; 3) second acute exercise condition in lab, symptom measures, and neuropsychological testing; and 4) 9-week exercise intervention or activity as usual outside of lab, with interview, symptom measures, and neuropsychological testing at three-week intervals.",[113],"Adverse Childhood Experiences","2026-07-16",{"date":116,"type":117},"2026-07-17","ACTUAL",{"date":119,"type":117},"2023-11-27",{"date":121,"type":107},"2027-06-04",{"name":5,"class":6},1]