[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100657038":3},{"organization":4,"outcomesModule":7,"designInfo":29,"detailedDescription":32,"studyPopulation":33,"armGroups":34,"interventions":28,"overallOfficials":38,"centralContacts":52,"locations":61,"responsibleParty":77,"collaborators":28,"id":81,"slug":82,"hasResults":83,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":28,"eligibilityCriteria":87,"healthyVolunteers":88,"sex":89,"minAge":90,"maxAge":91,"enrollmentInfo":92,"targetDuration":28,"studyType":95,"phases":28,"briefSummary":96,"conditions":97,"keywords":100,"overallStatus":103,"whyStopped":28,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":113},{"fullName":5,"class":6},"Saglik Bilimleri Universitesi","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":28},[9],{"measure":10,"description":11,"timeFrame":12},"Heart Rate Recovery After the 6-Minute Walk Test","Heart rate will be recorded at rest, immediately after the 6-Minute Walk Test, and at the 1st, 3rd, and 5th minutes of the recovery period to evaluate cardiovascular recovery following submaximal exercise.","Baseline and up to 5 minutes post-exercise",[14,18,21,25],{"measure":15,"description":16,"timeFrame":17},"Oxygen Saturation (SpO₂) During Post-Exercise Recovery","Oxygen saturation will be recorded at rest, immediately after the 6-Minute Walk Test, and at the 1st, 3rd, and 5th minutes of recovery.","Up to 5 minutes after the 6-Minute Walk Test",{"measure":19,"description":20,"timeFrame":12},"Borg Dyspnea\u002FFatigue Score During Post-Exercise Recovery","Dyspnea and fatigue will be assessed using the Borg Dyspnea\u002FFatigue Scale at rest, immediately after the 6-Minute Walk Test, and at the 1st, 3rd, and 5th minutes of recovery.",{"measure":22,"description":23,"timeFrame":24},"Morningness-Eveningness Characteristics","Morningness-eveningness characteristics will be assessed using the Morningness-Eveningness Questionnaire (MEQ).","Baseline",{"measure":26,"description":27,"timeFrame":24},"Sleep Quality","Sleep quality will be assessed using the Pittsburgh Sleep Quality Index (PSQI).",null,{"allocation":28,"interventionModel":28,"interventionModelDescription":28,"primaryPurpose":28,"observationalModel":30,"timePerspective":31,"maskingInfo":28},"COHORT","PROSPECTIVE","The study will include healthy volunteers aged 18-45 years. After written informed consent is obtained, participants will complete a sociodemographic information form, the Morningness-Eveningness Questionnaire, and the Pittsburgh Sleep Quality Index. Resting heart rate, oxygen saturation, and Borg dyspnea\u002Ffatigue scores will then be recorded, followed by the 6-Minute Walk Test. Physiological measurements will be repeated immediately after the test and at the 1st, 3rd, and 5th minutes of recovery.\n\nThe planned sample size is at least 124 participants. This was calculated using G\\*Power 3.1.9.7 based on a medium effect size (r=0.30), a significance level of 5% (α=0.05), and 90% statistical power, with an additional 10% allowance for possible data loss or missing data. Data will be analyzed using descriptive statistics, normality analyses, appropriate parametric or non-parametric comparison tests, correlation analyses, and multivariable regression analyses, with statistical significance set at p\\\u003C0.05.","Healthy volunteers aged 18-45 years who meet the study eligibility criteria and agree to participate voluntarily.",[35],{"label":36,"type":28,"description":37,"interventionNames":28},"Single Group","Healthy volunteers aged 18-45 years. Participants will complete a sociodemographic information form, the Morningness-Eveningness Questionnaire, and the Pittsburgh Sleep Quality Index. Resting heart rate, oxygen saturation, and Borg dyspnea\u002Ffatigue scores will be recorded, followed by the 6-Minute Walk Test. Physiological measurements will also be obtained immediately after the test and at the 1st, 3rd, and 5th minutes of recovery. No intervention will be administered",[39,43,47,50],{"name":40,"affiliation":41,"role":42},"Gamze Koyutürk, Asst Prof","Topkapı University","PRINCIPAL_INVESTIGATOR",{"name":44,"affiliation":45,"role":46},"Mehmet B Uyaroğlu, Asst Prof","Fenerbahce University","STUDY_DIRECTOR",{"name":48,"affiliation":28,"role":49},"Beyza Erdoğmuş, Dr","STUDY_CHAIR",{"name":51,"affiliation":45,"role":49},"Hüsna Güzel, MsC",[53,57],{"name":40,"role":54,"phone":55,"phoneExt":28,"email":56},"CONTACT","+905065798671","gamzealtinkaynak@gmail.com",{"name":58,"role":54,"phone":59,"phoneExt":28,"email":60},"Mehmet Burak Uyaroğlu, Asst Prof","5396545352","m.uyaroglu1@gmail.com",[62],{"facility":63,"status":28,"city":64,"state":28,"zip":28,"country":65,"countryCode":28,"cosmosGeoPoint":66,"geoPoint":71,"contacts":72},"İstanbul Topkapı University","Istanbul","Turkey (Türkiye)",{"type":67,"coordinates":68},"Point",[69,70],28.94966,41.01384,{"lat":70,"lon":69},[73],{"name":74,"role":54,"phone":75,"phoneExt":28,"email":76},"Gamze Koyutürk, Asst. Prof","5065798671","gamzekoyuturk@topkapi.edu.tr",{"type":42,"investigatorFullName":78,"investigatorTitle":79,"investigatorAffiliation":80,"oldNameTitle":28,"oldOrganization":28},"Gamze Altınkaynak","Assistant Professor","Istanbul Topkapi University","100657038","circadian-rhythm-and-cardiovascular-recovery-after-submaximal-exercise-100657038",false,"NCT07833956","Circadian Rhythm and Cardiovascular Recovery After Submaximal Exercise","Relationship Between Cardiovascular Recovery After a Submaximal Exercise Test and Circadian Rhythm: A 6-Minute Walk Test-Based Study","Inclusion Criteria:\n\n* Aged 18-45 years.\n* Being healthy.\n* Voluntarily agreeing to participate in the study.\n\nExclusion Criteria:\n\n* Presence of cardiovascular, pulmonary, neurological, or orthopedic disease.\n* Having a health problem that prevents exercise.\n* Use of medication that may affect exercise tolerance.\n* Pregnancy.",true,"ALL","18 Years","45 Years",{"count":93,"type":94},124,"ESTIMATED","OBSERVATIONAL","This cross-sectional, observational, and analytical study aims to investigate the relationship between morningness-eveningness characteristics and cardiovascular recovery after a submaximal exercise test in healthy individuals aged 18-45 years. Circadian preference will be assessed using the Morningness-Eveningness Questionnaire, sleep quality will be assessed using the Pittsburgh Sleep Quality Index, and cardiovascular recovery will be evaluated following the 6-Minute Walk Test",[98,99],"Circadian Rhythm","Health Adult Subjects",[98,101,102],"Cardiovascular Recovery","Submaximal Exercise Test","NOT_YET_RECRUITING","2026-09-16",{"date":106,"type":107},"2026-09-22","ACTUAL",{"date":109,"type":94},"2026-10-01",{"date":111,"type":94},"2027-03-31",{"name":5,"class":6},1]