[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648374":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":12,"centralContacts":12,"locations":12,"responsibleParty":35,"collaborators":40,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":44,"sex":50,"minAge":51,"maxAge":12,"enrollmentInfo":52,"targetDuration":12,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":12,"overallStatus":63,"whyStopped":12,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":12},{"fullName":5,"class":6},"Waymark","INDUSTRY",[8,13,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Arm 1: Unassisted care","NO_INTERVENTION","Clinician develops the care plan without AI assistance.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Arm 2: AI with safety guardrails","ACTIVE_COMPARATOR","AI-generated care plan produced with a safety-guardrail system prompt; no CITE.",[18],"Other: AI care plan with safety guardrails",{"label":20,"type":21,"description":22,"interventionNames":23},"Arm 3: AI with safety guardrails plus CITE","EXPERIMENTAL","AI-generated care plan with safety guardrails, then passed through CITE, which flags unsupported\u002Finappropriate recommendations with evidence citations for the clinician.",[24,18],"Other: CITE evidence-grounding retrieve-and-verify layer",[26,31],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":12},"OTHER","CITE evidence-grounding retrieve-and-verify layer","Reads the AI care-plan text and verifies each recommendation\u002Fclaim against a full-text evidence corpus; returns physician-facing flags (commission\u002Fconfabulation\u002Funsupported\u002Fomission) with verbatim quotes and citations. Clinician retains decision authority.",[20],{"type":27,"name":32,"description":33,"armGroupLabels":34,"otherNames":12},"AI care plan with safety guardrails","AI-generated care plan produced under a safety-guardrail system prompt.",[14,20],{"type":36,"investigatorFullName":37,"investigatorTitle":38,"investigatorAffiliation":39,"oldNameTitle":12,"oldOrganization":12},"PRINCIPAL_INVESTIGATOR","Sanjay Basu","Principal Investigator","University of California, San Francisco",[41],{"name":39,"class":27},"100648374","cite-clinical-inference-tethered-to-evidence---a-retrieve-and-verify-layer-for-ai-care-plans-100648374",false,"NCT07718893","CITE: Clinical Inference Tethered to Evidence - a Retrieve-and-verify Layer for AI Care Plans","A Randomized Controlled Trial of CITE (Clinical Inference Tethered to Evidence), an Evidence-Grounding Retrieve-and-Verify Layer That Flags Unsupported and Inappropriate Recommendations in AI-Generated Care Plans, Versus AI With Safety Guardrails Alone and Unassisted Care, in Medicaid Primary Care","CITE","INCLUSION CRITERIA:\n\n1. Age 18 years or older.\n2. Medicaid-enrolled and attributed to a participating Waymark primary care site.\n3. Primary care encounter that requires clinical reasoning (not administrative-only).\n4. English-language clinical documentation.\n\nEXCLUSION CRITERIA:\n\n1. Age less than 18 years.\n2. Hospice or palliative-care-exclusive care plan.\n3. Administrative-only or pharmacy-only encounter that does not surface a clinical decision to the supervising clinician.\n4. Encounter where the supervising clinician is the principal investigator.\n5. Enrollment in a competing AI-safety study within the prior 90 days.","ALL","18 Years",{"count":53,"type":54},240,"ESTIMATED","INTERVENTIONAL",[57],"NA","This trial evaluates CITE, a retrieve-and-verify layer that audits an AI-generated care plan against a full-text evidence corpus and flags patient-specific codifiable safety hazards to the clinician. The co-primary outcomes are how accurately CITE flags these hazards (sensitivity and specificity versus blinded clinician adjudication) and its clinician alert burden and acceptance, compared with AI care plans using safety guardrails alone and with unassisted clinician care, in Medicaid primary care.",[60,61,62],"Quality of Health Care","Patient Safety","Clinical Decision Support","NOT_YET_RECRUITING","2026-07-16",{"date":66,"type":67},"2026-07-22","ACTUAL",{"date":69,"type":54},"2026-09",{"date":71,"type":54},"2027-09",{"name":5,"class":6}]