[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100655041":3},{"organization":4,"outcomesModule":7,"designInfo":37,"detailedDescription":38,"studyPopulation":41,"armGroups":42,"interventions":52,"overallOfficials":38,"centralContacts":58,"locations":38,"responsibleParty":67,"collaborators":38,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":76,"sex":77,"minAge":78,"maxAge":38,"enrollmentInfo":79,"targetDuration":38,"studyType":82,"phases":38,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":90,"whyStopped":38,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":38},{"fullName":5,"class":6},"University of Pennsylvania","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":17},[9],{"measure":10,"description":11,"timeFrame":12},"HIV viral suppression","Binary, assigned to each client active at a participating site as of the end of each two-month (bimonthly) observation period. A client is classified as virally suppressed for a period if they had at least one viral load measured during the 6 months ending at the close of that period and the most recent such viral load was \\\u003C200 copies\u002FmL; clients with no viral load measured during that 6-month window are classified as not suppressed. This is consistent with the PDPH surveillance definition of viral suppression and allows every active client to be classified in every period (baseline city average 74.4%).","Every 6 months",[14],{"measure":15,"description":16,"timeFrame":12},"Engagement in care","Binary; a viral load or CD4 count measured within the 6-month lookback window for the observation period.",[18,21,25,28,31,34],{"measure":19,"description":20,"timeFrame":12},"Acceptability, appropriateness, feasibility of the B-OK Bottles","Implementation outcomes will be summarized descriptively overall and by site, time point, and stratum (pilot vs. newly trained). AIM\u002FIAM\u002FFIM scores and usage\u002Fpenetration measures will be compared across the three survey time points and between the passive-dissemination (pilot baseline) and structured-training conditions",{"measure":22,"description":23,"timeFrame":24},"Retention in care","Two or more laboratory results ≥91 days apart within a calendar year (PDPH surveillance definition; baseline 59.4%), analyzed based on a 12-month lookback for each observation period.","Every 12 months",{"measure":26,"description":27,"timeFrame":12},"Adoption and penetration","Proportion of MCMs using B-OK and proportion of clients with whom it is used",{"measure":29,"description":30,"timeFrame":12},"Delivery quality (fidelity)","MCM self-reported delivery of core B-OK elements and a brief role-play \u002F competency check during a post-implementation MCM interview",{"measure":32,"description":33,"timeFrame":12},"Maintenance\u002Fsustainability","Continued use across 6- and 12-month surveys; pilot-site sustainability",{"measure":35,"description":36,"timeFrame":12},"Client-reported reach and value","Client surveys and interviews",{"allocation":38,"interventionModel":38,"interventionModelDescription":38,"primaryPurpose":38,"observationalModel":39,"timePerspective":40,"maskingInfo":38},null,"COHORT","PROSPECTIVE","Clients: individuals living with HIV that receive case management from one of the 25 agencies that received Ryan White funding for HIV medical case management in Philadelphia in 2025\n\nMCM: Case managers that work at the 25 agencies that received Ryan White funding for HIV medical case management in Philadelphia in 2025",[43,48],{"label":44,"type":38,"description":45,"interventionNames":46},"Medical Case Managers","Medical case managers (MCMs) in Philadelphia's Ryan White-funded network",[47],"Behavioral: B-OK Bead Bottles",{"label":49,"type":38,"description":50,"interventionNames":51},"Clients living with HIV","Client are individuals who are living with HIV who receive care at one of Philadelphia's Ryan White-funded network",[47],[53],{"type":54,"name":55,"description":56,"armGroupLabels":57,"otherNames":38},"BEHAVIORAL","B-OK Bead Bottles","Medical case managers clients will receive a training on how to use B-OK bottles and will be given their own B-OK bottles. B-OK bottles are visual aids case managers can use explain how HIV treatment works in the body and to help clients visualize viral suppression. The bottles explain how HIV affects a person's health and how ART reduces viral load and eliminates HIV transmission risk.",[49,44],[59,64],{"name":60,"role":61,"phone":62,"phoneExt":38,"email":63},"Teniola Egbe, MPH, MBE","CONTACT","215-898-2939","tegbe@pennmedicine.upenn.edu",{"name":65,"role":61,"phone":38,"phoneExt":38,"email":66},"Aaron Richterman, PhD","Aaron.Richterman@Pennmedicine.upenn.edu",{"type":68,"investigatorFullName":38,"investigatorTitle":38,"investigatorAffiliation":38,"oldNameTitle":38,"oldOrganization":38},"SPONSOR","100655041","city-wide-implementation-and-evaluation-of-the-b-ok-bottles-for-hiv-treatment-adherence-support-in-the-philadelphia-ryan-white-medical-case-management-network-100655041",false,"NCT07807137","City-Wide Implementation and Evaluation of the B-OK Bottles for HIV Treatment Adherence Support in the Philadelphia Ryan White Medical Case Management Network","B-OK PDPH","Inclusion Criteria:\n\n* Medical Case Managers (MCM) from the 25 agencies that received Ryan White funding for HIV medical case management in Philadelphia in 2025\n* Clients living with HIV that receive case management from one of the 25 agencies that received Ryan White funding for HIV medical case management in Philadelphia in 2025\n\nExclusion Criteria:\n\n* Unwilling or unable to provide consent for study participation",true,"ALL","18 Years",{"count":80,"type":81},390,"ESTIMATED","OBSERVATIONAL","The researchers will conduct a hybrid implementation-effectiveness study of a city-wide B-OK rollout led by PDPH with research and evaluation support from the University of Pennsylvania. The rollout uses a randomized stepped-wedge design across the 21 MCM sites that have not previously received B-OK. The four pilot sites that received bottles without structured training in late 2023 will now also receive the full package and be trained but be analyzed as a separate stratum given prior exposure. The evaluation is organized under RE-AIM, with implementation outcomes defined using Proctor's taxonomy and contextual determinants assessed using CFIR.",[85],"HIV",[85,87,88,89],"Visual tools","Treatment adherence","Viral suppression","NOT_YET_RECRUITING","2026-09-15",{"date":93,"type":94},"2026-09-21","ACTUAL",{"date":96,"type":81},"2026-10-20",{"date":98,"type":81},"2029-03-31",{"name":5,"class":6}]