[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646702":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":30,"locations":25,"responsibleParty":36,"collaborators":25,"id":38,"slug":39,"hasResults":40,"nctId":41,"briefTitle":42,"officialTitle":43,"acronym":25,"eligibilityCriteria":44,"healthyVolunteers":40,"sex":45,"minAge":46,"maxAge":47,"enrollmentInfo":48,"targetDuration":25,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":25,"overallStatus":57,"whyStopped":25,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":25},{"fullName":5,"class":6},"The Fourth Affiliated Hospital of Zhejiang University School of Medicine","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard Care Group","ACTIVE_COMPARATOR","Patients in this group will receive standard orthopedic perioperative care and routine pain management protocols as per hospital guidelines, without clinical pharmacist intervention.",[13],"Other: Standard Perioperative Care",{"label":15,"type":16,"description":17,"interventionNames":18},"Clinical Pharmacist-Led Intervention Group","EXPERIMENTAL","Patients in this group will receive comprehensive pharmaceutical care led by a clinical pharmacist, including preoperative medication reconciliation, intraoperative monitoring, and postoperative analgesic optimization.",[19],"Other: Clinical Pharmacist-Led Pain Management",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Clinical Pharmacist-Led Pain Management","Description: Comprehensive pharmaceutical care including medication reconciliation, patient education, and analgesic regimen optimization.",[15],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Standard Perioperative Care","Patients receive standard orthopedic perioperative care and routine pain management protocols as per hospital guidelines, without clinical pharmacist intervention.",[9],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"qiniqn hu","CONTACT","+8618867962215","chawml@zju.edu.cn",{"type":37,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100646702","clinical-pharmacist-led-perioperative-pain-management-in-orthopedic-surgery-an-effectiveness-evaluation-100646702",false,"NCT07688486","Clinical Pharmacist-Led Perioperative Pain Management in Orthopedic Surgery: An Effectiveness Evaluation","Clinical Pharmacist-Involved Perioperative Pain Management Model Construction and Effectiveness Evaluation in Orthopedic Surgery","nclusion Criteria ： Patients scheduled for elective orthopedic surgery (e.g., total hip\u002Fknee arthroplasty, fracture fixation).\n\nAge ≥ 18 years. American Society of Anesthesiologists (ASA) physical status I-III. Able to understand and communicate pain intensity (e.g., use VAS score). Willing to provide informed consent.\n\nExclusion Criteria Emergency surgery or trauma patients unable to communicate. History of chronic opioid use or substance abuse. Severe cognitive impairment or psychiatric disorders preventing cooperation. Known allergy or contraindication to study medications (analgesics). Pregnant or breastfeeding women. Participation in other clinical trials that may interfere with this study.","ALL","18 Years","99 Years",{"count":49,"type":50},600,"ESTIMATED","INTERVENTIONAL",[53],"NA","This study aims to evaluate the effectiveness of a clinical pharmacist-led perioperative pain management model in orthopedic surgery. It is a randomized controlled trial involving patients undergoing major orthopedic procedures. Participants will be assigned to either a standard care group or an intervention group receiving comprehensive pharmaceutical care, including preoperative medication reconciliation, intraoperative monitoring, and postoperative analgesic optimization. The primary outcome is the incidence of moderate-to-severe postoperative pain. Secondary outcomes include opioid consumption, adverse drug reactions, and patient satisfaction. This study seeks to establish an evidence-based protocol for optimizing pain management in orthopedic settings.",[56],"Postoperative Pain","NOT_YET_RECRUITING","2026-07-01",{"date":60,"type":61},"2026-07-07","ACTUAL",{"date":63,"type":50},"2026-07-30",{"date":65,"type":50},"2027-11-30",{"name":5,"class":6}]