[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646295":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":44,"centralContacts":49,"locations":58,"responsibleParty":79,"collaborators":81,"id":87,"slug":88,"hasResults":89,"nctId":90,"briefTitle":91,"officialTitle":92,"acronym":10,"eligibilityCriteria":93,"healthyVolunteers":94,"sex":95,"minAge":10,"maxAge":96,"enrollmentInfo":97,"targetDuration":100,"studyType":101,"phases":10,"briefSummary":102,"conditions":103,"keywords":10,"overallStatus":106,"whyStopped":10,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"University of Manitoba","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Co-develop and implement a community-based perinatal education and support program using navigators",null,"The implementation of a community-based navigator to facilitate multiple points of pre and post-partum contact as well as individualized connection to preexisting and co-developed urban and northern pre- and post-natal supports, will increase rates of initiation and duration (≥6 month) of breastfeeding in the NextGen mothers from 58% to ≥75%.",[13],"Behavioral: Breastfeeding and perinatal education and support",{"label":15,"type":10,"description":16,"interventionNames":17},"Extend the scope of the NextGen Cohort","Community based point of care HbA1c testing will improve access to annual screening for pre-diabetes and diabetes in the Next Gen Cohort. CGM can detect early dysglycemia (below the threshold for the diagnosis of prediabetes) in young children at high risk for childhood-onset T2D. In addition, we hypothesize that CGM use will be well tolerated and feasible in young children.",[18,19],"Device: Purchasing HbA1c machines for communities","Device: Continuous Glucose Monitoring",{"label":21,"type":10,"description":22,"interventionNames":23},"Co-develop and implement community led land-based programming for parent(s) and preschool children","Land-based community programming for caregivers and children aged 4-5 years is feasible and will encourage healthy nutrition choices and physical activity. Ultimately, we hypothesize that this will improve the health and well-being of this high-risk population and improve cardiometabolic health.",[24],"Behavioral: Land-based Wellness Programming",[26,31,36,40],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":10},"BEHAVIORAL","Breastfeeding and perinatal education and support","Co-develop and implement a community-based perinatal education and support program using navigators to support breast feeding, maternal nutrition and activity, and early infancy\u002Fchildhood nutrition and activity.",[9],{"type":32,"name":33,"description":34,"armGroupLabels":35,"otherNames":10},"DEVICE","Purchasing HbA1c machines for communities","This will allow study participants to conduct earlier and more frequent screening for early dysglycemia, prediabetes and T2D.",[15],{"type":32,"name":37,"description":38,"armGroupLabels":39,"otherNames":10},"Continuous Glucose Monitoring","We will investigate the use of continuous glucose monitoring (CGM) to detect early dysglycemia in the Next Gen cohort.",[15],{"type":27,"name":41,"description":42,"armGroupLabels":43,"otherNames":10},"Land-based Wellness Programming","Co-develop and implement community led land-based programming for parent(s) and preschool children aged 4-5 years to encourage traditional nutrition and activities to maintain wellness.",[21],[45],{"name":46,"affiliation":47,"role":48},"Brandy A Wicklow, MD, MSc","University of Manitoba, Children's Hospital Research Institute of Manitoba","PRINCIPAL_INVESTIGATOR",[50,54],{"name":46,"role":51,"phone":52,"phoneExt":10,"email":53},"CONTACT","204-787-1222","bwicklow@hsc.mb.ca",{"name":55,"role":51,"phone":56,"phoneExt":10,"email":57},"Elizabeth AC Sellers, MD, MSc","204-787-3011","esellers@hsc.mb.ca",[59],{"facility":60,"status":10,"city":61,"state":62,"zip":63,"country":64,"countryCode":65,"cosmosGeoPoint":66,"geoPoint":71,"contacts":72},"Children's Hospital Research Institute of Manitoba\u002FUniversity of Manitoba","Winnipeg","Manitoba","R3E 3P4","Canada","CA",{"type":67,"coordinates":68},"Point",[69,70],-97.14704,49.8844,{"lat":70,"lon":69},[73,75],{"name":46,"role":51,"phone":74,"phoneExt":10,"email":53},"204781222",{"name":76,"role":51,"phone":77,"phoneExt":10,"email":78},"Research Coordinator","2042723064","NextGenStudy@chrim.ca",{"type":80,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[82,84],{"name":83,"class":6},"Children's Hospital Research Institute of Manitoba",{"name":85,"class":86},"Canadian Institutes of Health Research (CIHR)","OTHER_GOV","100646295","co-designing-enhanced-models-of-care-for-first-nations-children-at-risk-for-childhood-onset-type-2-diabetes-100646295",false,"NCT07692321","Co-designing Enhanced Models of Care for First Nations Children at Risk for Childhood-onset Type 2 Diabetes","Co-designing Enhanced Models of Care for First Nations Children at Risk for Childhood-onset Type 2 Diabetes: The Next Generation Birth Cohort.","Inclusion Criteria for the breastfeeding program:\n\n* Pregnant women with type 2 diabetes or no diabetes.\n* From self-identified Indigenous heritage (e.g., Cree, Oji-Cree, Métis, Anishinaabe, etc.) residing in the four Anisininew communities in the Island Lake region.\n* Are delivering in Manitoba.\n* Mother\u002FFather and children must be biological family members.\n\nExclusion Criteria from the breastfeeding program:\n\n* Parents or children with type 1 diabetes.\n* Residing outside of Manitoba.\n\nInclusion criteria for the CGM pro",true,"ALL","18 Years",{"count":98,"type":99},600,"ESTIMATED","4 Years","OBSERVATIONAL","The overall objective: to co-design and implement targeted and timely community led strategies to improve the health of the Next Generation and end the intergenerational impact of T2D in this population.",[104,105],"Type 2 Diabetes","Gestational Diabetes Mellitus (GDM)","NOT_YET_RECRUITING","2026-07-30",{"date":109,"type":110},"2026-08-03","ACTUAL",{"date":112,"type":99},"2026-08-31",{"date":114,"type":99},"2031-03-31",{"name":5,"class":6},1]