[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100480090":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":13,"studyPopulation":17,"armGroups":13,"interventions":13,"overallOfficials":13,"centralContacts":18,"locations":24,"responsibleParty":129,"collaborators":13,"id":131,"slug":132,"hasResults":133,"nctId":134,"briefTitle":135,"officialTitle":136,"acronym":137,"eligibilityCriteria":138,"healthyVolunteers":133,"sex":139,"minAge":140,"maxAge":141,"enrollmentInfo":142,"targetDuration":145,"studyType":146,"phases":13,"briefSummary":147,"conditions":148,"keywords":13,"overallStatus":27,"whyStopped":13,"lastUpdateSubmitDate":150,"lastUpdatePostDateStruct":151,"startDateStruct":154,"completionDateStruct":156,"leadSponsor":158,"locationsCount":159},{"fullName":5,"class":6},"Rapid Medical","INDUSTRY",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Association between successful reperfusion* and cognitive benefit**","\\*successful reperfusion is defined as eTICI ≥2b50 with the Tigertriever device.\n\n* Cognitive benefit is defined as change in Montreal Cognitive Assessment (MoCA) of 1.5 Standard Deviations (SD) from 4 days post treatment (or discharge if earlier) and 180 days post treatment; or MoCA ≥26 at 180 days post treatment.","180 days post treatment",null,{"allocation":13,"interventionModel":13,"interventionModelDescription":13,"primaryPurpose":13,"observationalModel":15,"timePerspective":16,"maskingInfo":13},"COHORT","PROSPECTIVE","The COGNITIVE Study will include male or female subjects age 18-75 who present with LVO and treated with the Tigertriever as indicated per approved IFU.",[19],{"name":20,"role":21,"phone":22,"phoneExt":13,"email":23},"Walid Haddad, Dr.","CONTACT","+972 72 2503331","walid@rapid-medical.com",[25,47,63,80,96,112],{"facility":26,"status":27,"city":28,"state":29,"zip":30,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"University of California","RECRUITING","Los Angeles","California","90095","United States","US",{"type":34,"coordinates":35},"Point",[36,37],-118.24368,34.05223,{"lat":37,"lon":36},[40,44],{"name":41,"role":21,"phone":42,"phoneExt":13,"email":43},"Saima Chaabane","310-794-4482","SChaabane@mednet.ucla.edu",{"name":45,"role":46,"phone":13,"phoneExt":13,"email":13},"Tateshima Satoshi, MD","PRINCIPAL_INVESTIGATOR",{"facility":48,"status":27,"city":49,"state":29,"zip":50,"country":31,"countryCode":32,"cosmosGeoPoint":51,"geoPoint":55,"contacts":56},"University of California, Irvine","Orange","92868",{"type":34,"coordinates":52},[53,54],-117.85311,33.78779,{"lat":54,"lon":53},[57,61],{"name":58,"role":21,"phone":59,"phoneExt":13,"email":60},"Elizabeth Salcedo-Rodriguez","949-824-9320","esalced1@hs.uci.edu",{"name":62,"role":46,"phone":13,"phoneExt":13,"email":13},"Shuichi Suzuki, MD Suzuki, MD",{"facility":64,"status":27,"city":65,"state":66,"zip":67,"country":31,"countryCode":32,"cosmosGeoPoint":68,"geoPoint":72,"contacts":73},"Corewell Health Research Institute","Grand Rapids","Michigan","49503",{"type":34,"coordinates":69},[70,71],-85.66809,42.96336,{"lat":71,"lon":70},[74,78],{"name":75,"role":21,"phone":76,"phoneExt":13,"email":77},"Stephanie Mueller","616-267-1072","Stephanie.Mueller@corewellhealth.org",{"name":79,"role":46,"phone":13,"phoneExt":13,"email":13},"Paul Mazaris, MD",{"facility":81,"status":27,"city":82,"state":82,"zip":83,"country":31,"countryCode":32,"cosmosGeoPoint":84,"geoPoint":88,"contacts":89},"Westchester Medical Center","New York","10595",{"type":34,"coordinates":85},[86,87],-74.00597,40.71427,{"lat":87,"lon":86},[90,94],{"name":91,"role":21,"phone":92,"phoneExt":13,"email":93},"Cristina Falo","914-493-8194","cristina.falo@wmchealth.org",{"name":95,"role":46,"phone":13,"phoneExt":13,"email":13},"Chirag Gandhi",{"facility":97,"status":27,"city":98,"state":82,"zip":99,"country":31,"countryCode":32,"cosmosGeoPoint":100,"geoPoint":104,"contacts":105},"Montefiore Medical Center The University Hospital for Albert Einstein College of Medicine","The Bronx","10467",{"type":34,"coordinates":101},[102,103],-73.86641,40.84985,{"lat":103,"lon":102},[106,110],{"name":107,"role":21,"phone":108,"phoneExt":13,"email":109},"Genesis Liriano","718-920-2469","gliriano@montefiore.org",{"name":111,"role":46,"phone":13,"phoneExt":13,"email":13},"David Altschul, MD",{"facility":113,"status":27,"city":114,"state":115,"zip":116,"country":31,"countryCode":32,"cosmosGeoPoint":117,"geoPoint":121,"contacts":122},"The Hospital of the University of Pennsylvania","Philadelphia","Pennsylvania","19104",{"type":34,"coordinates":118},[119,120],-75.16362,39.95238,{"lat":120,"lon":119},[123,127],{"name":124,"role":21,"phone":125,"phoneExt":13,"email":126},"Leah Coghlan","215-341-5864","Leah.Coghlan@pennmedicine.upenn.edu",{"name":128,"role":46,"phone":13,"phoneExt":13,"email":13},"Shish Srinivasan, MD",{"type":130,"investigatorFullName":13,"investigatorTitle":13,"investigatorAffiliation":13,"oldNameTitle":13,"oldOrganization":13},"SPONSOR","100480090","cognition-and-imaging-with-tigertriever-100480090",false,"NCT05531461","Cognition and Imaging With Tigertriever","COGNITIVE Study- Cognition and Imaging With Tigertriever","COGNITIVE","Inclusion Criteria:\n\n1. Patients admitted with large vessel occlusion (LVO) and treated with the Tigertriever, as indicated per the approved IFU.\n2. Tigertriever was used as the first line treatment in the target vessel.\n3. A signed informed consent.\n4. Age 18-75 years (inclusive).\n5. No known significant pre-stroke disability (pre-stroke mRS 0 or 1).\n\nExclusion Criteria:\n\n1. Use of any other IA recanalization device prior to the Tigertriever in the target vessel, including aspiration catheter.\n2. Evidence of acute brain hemorrhage on CT and\u002For MRI at admission.\n3. Prior hemorrhage, stroke, thrombolysis, and\u002For endovascular therapy in the last 3 months.\n4. Probable cerebral amyloid angiopathy.\n5. Pre-stroke diagnosed dementia and\u002For prescribed cholinesterase inhibitors.\n6. Pre-stroke diagnosed and\u002For currently treated major depression.\n7. Pre-stroke learning or intellectual disability.\n8. Anticipated inability to obtain 6-month follow-up assessments.\n\n   \\-","ALL","18 Years","75 Years",{"count":143,"type":144},424,"ESTIMATED","1 Year","OBSERVATIONAL","The objective of the COGNITIVE Study is to evaluate whether successful reperfusion with Tigertriever is associated with cognitive benefit.",[149],"Stroke","2026-10-06",{"date":152,"type":153},"2026-10-09","ACTUAL",{"date":155,"type":153},"2024-10-28",{"date":157,"type":144},"2027-11",{"name":5,"class":6},6]