[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100647104":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":31,"locations":40,"responsibleParty":57,"collaborators":25,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":25,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":25,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":25,"overallStatus":78,"whyStopped":25,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Shengjing Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental Group: Sacral Nerve Root Magnetic Stimulation + Active Ultrasound Therapy","EXPERIMENTAL","Magnetic stimulation: round coil over S3 foramina, verified by toe twitch. 20 Hz intermittent, 1000 pulses\u002Fsession, intensity 55%-100% max. Active ultrasound: after saline infusion with pressure monitoring (stop at 40 cmH₂O or discomfort), 1.0 MHz, 1.5-2.0 W\u002Fcm², 1000 μs PRP, 1:4 duty cycle, 200 μs pulse duration. Probe moved over suprapubic area, 20 min\u002Fsession. Both given once daily, 7 days\u002Fweek for 3 weeks. Stop immediately if pressure \\>40 cmH₂O or any discomfort.",[13],"Device: Transcranial Magnetic Stimulation (TMS) Device \u002FUltrasound therapy device",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group： Sacral Nerve Root Magnetic Stimulation + Sham Ultrasound Therapy","SHAM_COMPARATOR","Magnetic stimulation: identical to Arm 1. Sham ultrasound: same probe, same interface settings (frequency, intensity display, pulse parameters) but zero output power. Bladder infusion and pressure monitoring same as Arm 1. Probe moved over suprapubic area for 20 min\u002Fsession. Treatment frequency and duration identical to Arm 1 (once daily, 7 days\u002Fweek, 3 weeks). Stop if pressure \\>40 cmH₂O or discomfort.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Transcranial Magnetic Stimulation (TMS) Device \u002FUltrasound therapy device","Participants receive the intervention assigned to their group 7 days per week for 3 weeks.",[15,9],null,[27],{"name":28,"affiliation":29,"role":30},"Xue Jiang","Rehabilitation Center of Shengjing Hospital, China Medical University","PRINCIPAL_INVESTIGATOR",[32,36],{"name":28,"role":33,"phone":34,"phoneExt":25,"email":35},"CONTACT","+86 18940254064","jiangxueruby@163.com",{"name":37,"role":33,"phone":38,"phoneExt":25,"email":39},"Kaixuan Zhu","17860690831","2033055053@qq.com",[41],{"facility":42,"status":25,"city":43,"state":25,"zip":25,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Rehabilitation Center of Shengjing Hospital, China Medical University, shenyang, Liaoning 110000","Shenyang","China","CN",{"type":47,"coordinates":48},"Point",[49,50],123.43278,41.79222,{"lat":50,"lon":49},[53,55],{"name":28,"role":33,"phone":54,"phoneExt":25,"email":35},"+86 189 4025 4064",{"name":37,"role":33,"phone":56,"phoneExt":25,"email":39},"+8617860690831",{"type":30,"investigatorFullName":28,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Associate Professor","100647104","combined-magnetic-stimulation-and-ultrasound-for-detrusor-overactivity-in-sci-100647104",false,"NCT07704268","Combined Magnetic Stimulation and Ultrasound for Detrusor Overactivity in SCI","A Randomized, Double-Blind, Sham-Controlled Trial of Sacral Nerve Root High-Frequency Magnetic Stimulation Combined With Ultrasound Therapy for Detrusor Overactivity in Patients With Spinal Cord Injury","Inclusion Criteria:\n\n1. Diagnosis of spinal cord injury (SCI) above the sacral level according to the International Standards for Neurological Classification of Spinal Cord Injury (revised 2011), confirmed by CT or MRI;\n2. Detrusor overactivity confirmed by urodynamic study;\n3. No severe urinary system diseases such as tumors, stones, infection, or organic urinary tract obstruction;\n4. No severe hepatic\u002Frenal insufficiency, pulmonary, or cardiovascular diseases;\n5. Aged 18-80 years;\n6. Able to understand and comply with the required examinations, rehabilitation assessments, and treatment, and provide written informed consent.\n\nExclusion Criteria:\n\n1. Unstable vital signs or critically ill condition;\n2. Severe autonomic dysreflexia;\n3. Presence of metallic implants within 10 cm of the magnetic stimulation treatment area;\n4. Any other diseases or conditions that may interfere with the study outcomes.","ALL","18 Years","80 Years",{"count":70,"type":71},44,"ESTIMATED","INTERVENTIONAL",[74],"NA","This clinical trial aims to investigate whether the combination of high-frequency sacral nerve root magnetic stimulation and bladder-directed ultrasound therapy can effectively improve detrusor overactivity (involuntary bladder contractions) and related voiding dysfunctions in patients with spinal cord injury. The main questions it seeks to answer are:\n\nWhat is the effect of high-frequency sacral nerve root magnetic stimulation on detrusor overactivity and bladder function in patients with spinal cord injury?\n\nWhat is the effect of bladder-directed ultrasound therapy on detrusor overactivity and bladder wall compliance in patients with spinal cord injury?\n\nIs the combination of these two treatment modalities superior to magnetic stimulation alone?",[77],"Spinal Cord Injuries","NOT_YET_RECRUITING","2026-07-09",{"date":81,"type":82},"2026-07-15","ACTUAL",{"date":84,"type":71},"2026-07-10",{"date":86,"type":71},"2027-04-30",{"name":5,"class":6},1]