[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100647020":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":29,"locations":35,"responsibleParty":50,"collaborators":11,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":56,"sex":62,"minAge":63,"maxAge":11,"enrollmentInfo":64,"targetDuration":11,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":38,"whyStopped":11,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Namik Kemal University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients operated with FANS-UAS","EXPERIMENTAL",null,[13],"Device: flexible and navigable ureteral access sheath",{"label":15,"type":16,"description":11,"interventionNames":17},"Patients operated with conventional-UAS","ACTIVE_COMPARATOR",[18],"Device: conventional ureteral access sheath",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"DEVICE","flexible and navigable ureteral access sheath","Patients of RIRS operated with flexible and navigable ureteral access sheath",[9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"conventional ureteral access sheath","Patients of RIRS operated with conventional ureteral access sheath",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},"mehmet fatih M. şahin, associate professor","CONTACT","+90 555 551 1871","mfatihsahin@gmail.com",[36],{"facility":37,"status":38,"city":39,"state":11,"zip":11,"country":40,"countryCode":11,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Tekirdag Namık Kemal University","RECRUITING","Tekirdağ","Turkey (Türkiye)",{"type":42,"coordinates":43},"Point",[44,45],27.51101,40.9781,{"lat":45,"lon":44},[48],{"name":49,"role":32,"phone":33,"phoneExt":11,"email":34},"Mehmet F. Şahin, associate professor",{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Mehmet Fatih Şahin","Associate Professor","100647020","comparison-of-fans-vs-conventional-ureteral-access-sheath-in-rirs-on-postoperative-acute-kidney-injury-100647020",false,"NCT07685587","COMPARISON OF FANS VS CONVENTIONAL URETERAL ACCESS SHEATH in RIRS on POSTOPERATIVE ACUTE KIDNEY INJURY","Comparison of the Effects of Flexible and Navigable Suction With Conventional Ureteral Access Sheaths During Retrograde Intrarenal Surgery on Postoperative Acute Renal Injury With IL-18 and L-FABP Biomarkers: A Prospective Randomised Study","FANS","Inclusion Criteria:\n\n* Being 18 years of age or older\n* Having a planned RIRS operation\n* Providing written informed consent\n\nExclusion Criteria:\n\n* Patients who do not give consent\n* Patients who will undergo combined surgery\n* Patients who have previously undergone endoscopic stone surgery\n* Being under 18 years of age\n* Patients with chronic kidney failure\n* Patients with kidney malformations\n* Patients with a solitary kidney\n* Patients using nephrotoxic drugs","ALL","18 Years",{"count":65,"type":66},108,"ESTIMATED","INTERVENTIONAL",[69],"NA","Kidney stone disease is a common condition, and retrograde intrarenal surgery (RIRS) is a minimally invasive procedure frequently used to remove kidney stones. During RIRS, pressure inside the kidney can increase, which may contribute to temporary kidney injury. New aspiration-enabled access sheath systems have been developed to better control this pressure by continuously removing irrigation fluid during surgery. This study will compare aspiration and conventional access sheath systems to determine whether improved pressure control reduces early kidney injury. Blood and urine biomarkers (IL-18 and L-FABP), which can detect kidney damage earlier than standard kidney function tests, will be measured before and after surgery. The results may help identify surgical techniques that better protect kidney function and improve the safety of kidney stone treatment for patients.",[72],"Urolithiasis",[74,75,76,77],"retrograde intrarenal surgery","acute kidney injury","IL-18","L-FABP","2026-07-01",{"date":80,"type":81},"2026-07-06","ACTUAL",{"date":83,"type":81},"2026-05-04",{"date":85,"type":66},"2027-06-30",{"name":5,"class":6},1]