[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100652223":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":25,"locations":30,"responsibleParty":56,"collaborators":25,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":25,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":25,"enrollmentInfo":67,"targetDuration":25,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":83,"overallStatus":87,"whyStopped":25,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"University of Calgary","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Single Shot Interscalene Block","ACTIVE_COMPARATOR","This Control Group will receive a single-shot interscalene block, which is considered one of the standard of care analgesic modality for shoulder surgery.",[13],"Drug: Interscalene Block",{"label":15,"type":16,"description":17,"interventionNames":18},"Continuous Interscalene Block","EXPERIMENTAL","This Interventional Group will receive a continuous interscalene block via a catheter for a duration of 48 hours with ropivacaine 0.2% at a fixed 5 mL\u002Fhour rate.",[19],"Drug: Continuous interscalene nerve block",[21,26],{"type":22,"name":23,"description":17,"armGroupLabels":24,"otherNames":25},"DRUG","Continuous interscalene nerve block",[15],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Interscalene Block","This control group will receive a single shot interscalene block with 20 mL of ropivicaine 0.2%.",[9],[31],{"facility":32,"status":25,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"South Health Campus","Calgary","Alberta","T3M 1M4","Canada","CA",{"type":39,"coordinates":40},"Point",[41,42],-114.08529,51.05011,{"lat":42,"lon":41},[45,50,53],{"name":46,"role":47,"phone":48,"phoneExt":25,"email":49},"Joanna Dr Fifen, MD, PhD","CONTACT","403-956-3690","Joanna.Fifen@albertahealthservices.ca",{"name":51,"role":52,"phone":25,"phoneExt":25,"email":25},"Joanna Fifen, MD, PhD","PRINCIPAL_INVESTIGATOR",{"name":54,"role":55,"phone":25,"phoneExt":25,"email":25},"Cyril Nader, MD","SUB_INVESTIGATOR",{"type":57,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100652223","continuous-interscalene-blocks-and-rebound-pain-100652223",false,"NCT07770165","Continuous Interscalene Blocks and Rebound Pain","Evaluation of the Effect of Continuous Interscalene Blocks on Rebound Pain Compared to Single-Shot Interscalene Blocks in Total Shoulder Arthroplasty : A Randomized-Controlled Trial","Inclusion Criteria:\n\n* Adults aged \\>18 years of age\n* ASA I-III\n* Scheduled for elective ambulatory total shoulder arthroplasty.\n\nExclusion Criteria:\n\n* ASA IV\n* Revision surgery\n* Contraindication to regional anesthesia (such as allergy to local anesthetics, systemic anticoagulation, local infection)\n* Preoperative chronic pain or opioid use\n* Preoperative drug dependency\n* Severe respiratory disease or contralateral diaphragmatic paralysis\n* Patient refusal.","ALL","18 Years",{"count":68,"type":69},154,"ESTIMATED","INTERVENTIONAL",[72],"NA","The primary objectives of this present study are to examine whether a continuous interscalene block of a total duration of 48 hours reduces the incidence of rebound pain comparatively to single-shot interscalene block, through the evaluation of the NRS scores at rest and on movement in the postoperative period at 24, 48, 72 and 96 hours as well as the total opioid consumption in the same timeframe for patients undergoing total shoulder arthroplasty.\n\nRebound pain has been defined in some studies as the \"the transition from well-controlled pain (numerical rating scale \\[NRS\\] ≤3) while the block is working to severe pain (NRS ≥7) within 24 h of block performance.\"",[75,76,77,78,79,80,81,82],"Total Shoulder Arthroplasty","Reverse Total Shoulder Arthroplasty","Interscalene Analgesia","Interscalene Blocks","Interscalene Nerve Block","Orthopedic Surgery Patients","Locoregional Anaesthesia","Rebound Pain",[84,85,86,15,75,76,82],"Interscalene","Nerve Block","Catheter","NOT_YET_RECRUITING","2026-08-17",{"date":90,"type":91},"2026-08-19","ACTUAL",{"date":93,"type":69},"2026-10",{"date":95,"type":69},"2027-05",{"name":5,"class":6},1]