[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100647510":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":23,"centralContacts":23,"locations":23,"responsibleParty":24,"collaborators":23,"id":26,"slug":27,"hasResults":28,"nctId":29,"briefTitle":30,"officialTitle":31,"acronym":23,"eligibilityCriteria":32,"healthyVolunteers":28,"sex":33,"minAge":34,"maxAge":23,"enrollmentInfo":35,"targetDuration":23,"studyType":38,"phases":39,"briefSummary":41,"conditions":42,"keywords":45,"overallStatus":49,"whyStopped":23,"lastUpdateSubmitDate":50,"lastUpdatePostDateStruct":51,"startDateStruct":54,"completionDateStruct":56,"leadSponsor":58,"locationsCount":23},{"fullName":5,"class":6},"Henan Provincial People's Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Immediate Intervention Group","EXPERIMENTAL","This cluster receives the intervention during Years 1, 2, and 3.",[13],"Other: ACF strategy",{"label":15,"type":6,"description":16,"interventionNames":17},"Delayed Intervention Group","This cluster serves as a no-intervention control during Years 1 and 2, and then transitions to receive the same intervention during Year 3.",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"ACF strategy","An ACF strategy integrating computer-aided diagnosis and GeneXpert MTB\u002FRIF testing.",[15,9],null,{"type":25,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR","100647510","copd-ptb-screening-trial-in-henan-china-100647510",false,"NCT07706972","COPD-PTB Screening Trial in Henan, China","Epidemiological Status and Intervention Technologies for COPD and Pulmonary Tuberculosis Comorbidity in Primary Care Settings in Henan Province, China","Inclusion Criteria:\n\n1. aged 18 years or older;\n2. residence in the local area for at least six months;\n3. providing written informed consent to participate in the study.\n\nExclusion Criteria:\n\n1. inability to provide informed consent or complete the questionnaire;\n2. contraindications to CT scanning;\n3. current pregnancy.","ALL","18 Years",{"count":36,"type":37},25000,"ESTIMATED","INTERVENTIONAL",[40],"NA","The goal of this trial is to evaluate the effectiveness of an active case-finding (ACF) strategy for detecting pulmonary tuberculosis (PTB) among patients with chronic obstructive pulmonary disease (COPD) in primary care settings in Henan Province, China. It will also assess the epidemiological status of COPD-PTB comorbidity in this population and evaluate the feasibility of the ACF strategy in real-world primary care settings.\n\nThis is a stepped-wedge cluster randomized controlled trial. Specifically, the intervention group will receive the ACF strategy in Year 1, Year 2, and Year 3, while the control group will receive routine follow-up care in Year 1 and Year 2, and will transition to receive the ACF intervention in Year 3. All clusters will eventually receive the ACF intervention.\n\nThe main questions it aims to answer are:\n\nDoes the ACF strategy decrease the prevalence of PTB among COPD patients compared with routine passive case-finding? What are the current prevalence and epidemiological characteristics of COPD-PTB comorbidity in primary care settings in Henan Province?\n\nParticipants will:\n\nReceive ACF screening during their routine COPD follow-up visits in the intervention phase.\n\nContinue their usual COPD care as prescribed by their healthcare providers. If diagnosed with PTB through ACF screening, participants will be referred to designated hospitals for treatment in accordance with the national standardized tuberculosis treatment protocol.",[43,44],"Chronic Obstructive Pulmonary Disease (COPD)","TB - Tuberculosis",[46,47,48],"COPD","TB","active case-finding strategy","NOT_YET_RECRUITING","2026-07-15",{"date":52,"type":53},"2026-07-16","ACTUAL",{"date":55,"type":37},"2026-07-20",{"date":57,"type":37},"2029-06-30",{"name":5,"class":6}]