[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646027":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":25,"locations":29,"responsibleParty":51,"collaborators":53,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":61,"sex":67,"minAge":68,"maxAge":25,"enrollmentInfo":69,"targetDuration":25,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":25,"overallStatus":79,"whyStopped":25,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Minneapolis Heart Institute Foundation","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"CT-guided PCI","EXPERIMENTAL","Pre-procedural planning will be completed using the participant's CT, and tools including Heartflow's PCI Navigator",[13],"Procedure: CT-guided PCI",{"label":15,"type":16,"description":17,"interventionNames":18},"Routine PCI","ACTIVE_COMPARATOR","Participants randomized to this arm will undergo standard-of-care PCI without pre-procedural planning based on CT",[19],"Procedure: Routine PCI",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Participants randomized to CT-guided PCI will have their clinically available CCTAs analyzed using commercially available software to create a pre-procedural plan, which will be used to help guide the procedure",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Participants randomized to routine PCI will not have their CCTA's analyzed pre-procedure. The investigator may use intravascular imaging and pre-PCI FFR, but these are not mandated. The investigator will use the information obtained from the coronary angiogram to treat any coronary artery disease that is present.",[15],[30],{"facility":5,"status":25,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Minneapolis","Minnesota","55407","United States","US",{"type":37,"coordinates":38},"Point",[39,40],-93.26384,44.97997,{"lat":40,"lon":39},[43,48],{"name":44,"role":45,"phone":46,"phoneExt":25,"email":47},"Olga Mastrodemos","CONTACT","612-863-4768","olga.mastrodemos@allina.com",{"name":49,"role":50,"phone":25,"phoneExt":25,"email":25},"Yader Sandoval, MD","PRINCIPAL_INVESTIGATOR",{"type":52,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[54,57],{"name":55,"class":56},"HeartFlow, Inc.","INDUSTRY",{"name":58,"class":56},"Shockwave Medical, Inc.","100646027","coronary-computed-tomography-angiography-ccta-for-the-pre-procedural-planning-of-percutaneous-coronary-intervention-100646027",false,"NCT07691502","Coronary Computed Tomography Angiography (CCTA) for the Pre-procedural Planning of Percutaneous Coronary Intervention","Coronary Computed Tomography Angiography (CCTA) for the Pre-procedural Planning of Percutaneous Coronary Intervention: A Randomized Trial of Routine PCI Versus CCTA-guided PCI","CT-PLAN-PCI","Inclusion Criteria:\n\n* At least one moderate-severe coronary stenosis on CCTA with an FFRCT ≤0.80 involving no more than two vessels (i.e. target lesion(s) must be FFRCT eligible)\n* Referral for non-emergent PCI of at least one de novo stenosis in a native coronary artery with a reference diameter ≥2 mm on CCTA.\n\nExclusion Criteria:\n\n* Multivessel CAD involving ≥3 vessels.\n* Severe left main disease \\>50%\n* Prior CABG\n* Prior PCI in target vessel\n* Planned CABG\n* Chronic coronary total occlusion in the target vessel\n* ST-elevation myocardial infarction\n* Emergent PCI\n* Cardiac arrest\n* Cardiogenic shock\n* Scenarios where FFRCT is not possible: inadequate CCTA quality for FFRCT, small vessels \\\u003C2 mm, with stents at the target vessel.\n* Unstable high-risk NSTE-ACS (hemodynamic instability, refractory angina, unstable arrhythmias, persistent ischemia).\n* Patients who are pregnant or nursing or plan to be pregnant in the period up to 2 years following the index procedure will not be approached due to exposure to fluoroscopy.","ALL","22 Years",{"count":70,"type":71},200,"ESTIMATED","INTERVENTIONAL",[74],"NA","The CT-PLAN PCI trial will evaluate whether CCTA-guided PCI improves procedural efficiency compared with routine PCI (without pre-procedural CCTA-guidance for PCI planning) using procedural time as the primary endpoint. Key secondary outcomes will include contrast volume, radiation dose, fluoroscopy time, resource utilization, and periprocedural outcomes including post-PCI physiology, and peri-procedural myocardial injury measured by high-sensitivity cardiac troponin assays.",[77,78],"Coronary Artery Disease","CT","NOT_YET_RECRUITING","2026-07-08",{"date":82,"type":83},"2026-07-10","ACTUAL",{"date":85,"type":71},"2026-07-15",{"date":87,"type":71},"2028-12-01",{"name":5,"class":6},1]