[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649193":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":39,"responsibleParty":55,"collaborators":25,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":59,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":25,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":79,"overallStatus":87,"whyStopped":25,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Nantes University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Manual vacuum aspiration (MVA)","EXPERIMENTAL","Outpatient manual vacuum aspiration under local anesthesia and inhaled analgesia (MEOPA).",[13],"Procedure: Manual vacuum aspiration (MVA)",{"label":15,"type":16,"description":17,"interventionNames":18},"Electric aspiration in the operating room under general or regional anesthesia. Electric aspiration","ACTIVE_COMPARATOR","Electric aspiration in the operating room under general or regional anesthesia. Performed in the operating room under general or regional anesthesia, using an electric suction device and appropriate cannula. Post-procedure pelvic ultrasound to confirm complete evacuation.",[19],"Procedure: Electric aspiration (EA)",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Performed in consultation under local anesthesia and inhaled analgesia, using a manual vacuum aspirator and appropriate cannula. Post-procedure pelvic ultrasound to confirm complete evacuation.",[9],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Electric aspiration (EA)","Performed in the operating room under general or regional anesthesia, using an electric suction device and appropriate cannula. Post-procedure pelvic ultrasound to confirm complete evacuation.",[15],[31],{"name":32,"affiliation":5,"role":33},"Thibault Thubert, Pr","PRINCIPAL_INVESTIGATOR",[35],{"name":32,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","+33253482443","thibault.thubert@chu-nantes.fr",[40],{"facility":41,"status":25,"city":42,"state":25,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"CHU de Nantes","Nantes","44000","France","FR",{"type":47,"coordinates":48},"Point",[49,50],-1.55336,47.21725,{"lat":50,"lon":49},[53],{"name":32,"role":36,"phone":54,"phoneExt":25,"email":38},"+33 2 53 48 24 43",{"type":56,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100649193","cost-utility-analysis-of-outpatient-manual-vacuum-aspiration-versus-operating-room-electric-aspiration-for-the-management-of-first-trimester-miscarriage-100649193",false,"NCT07732231","Cost-utility Analysis of Outpatient Manual Vacuum Aspiration Versus Operating Room Electric Aspiration for the Management of First-trimester Miscarriage","Cost-utility Analysis of Outpatient Manual Vacuum Aspiration Versus Operating Room Electric Aspiration for the Management of First-trimester Miscarriage (ASPIR Study)","ASPIR","Inclusion Criteria:\n\n* Female, aged 18-44 years\n* Ultrasound-confirmed first-trimester miscarriage requiring surgical management\n* Gestational age between 5 and 12 weeks of amenorrhea\n* Incomplete spontaneous abortion or ongoing non-viable pregnancy\n* Patient able to provide oral informed consent\n\nExclusion Criteria:\n\n* Complete expulsion of pregnancy (endometrial thickness \\\u003C 15 mm)\n* Choice of medical treatment with misoprostol\n* Elective termination of pregnancy\n* Unwanted pregnancy\n* Pregnancy of unknown location, molar pregnancy\n* Known uterine malformation\n* Prior surgical aspiration for the current pregnancy\n* Intrauterine device in place\n* Contraindicating medications (e.g. anticoagulants)\n* Protected adults (under guardianship)\n* Inability to complete study questionnaires\n* Lack of social security coverage\n* Haemorrhagic miscarriage","FEMALE","18 Years","44 Years",{"count":69,"type":70},860,"ESTIMATED","INTERVENTIONAL",[73],"NA","The ASPIR study aims to evaluate the cost-utility of outpatient manual vacuum aspiration compared with operating room electric aspiration for the management of first-trimester miscarriage. It is hypothesized that manual aspiration will demonstrate equivalent clinical efficacy and patient quality of life while reducing healthcare costs.",[76,77,78],"Miscarriage","Pregnancy Loss","First Trimester Pregnancy",[80,81,82,83,84,85,86],"Manual vacuum aspiration","Electric aspiration","Cost-effectiveness","Health economics","Gynecology","Pregnancy loss","miscarriage","NOT_YET_RECRUITING","2026-07-27",{"date":90,"type":91},"2026-07-28","ACTUAL",{"date":93,"type":70},"2026-10-01",{"date":95,"type":70},"2029-10-01",{"name":5,"class":6},1]