[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650195":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":38,"locations":44,"responsibleParty":61,"collaborators":42,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":42,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":42,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":47,"whyStopped":42,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Ankara Etlik City Hospital","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Combined Contrast Therapy with Intermittent Compression","EXPERIMENTAL","Participants in this group will receive combined contrast therapy with intermittent pneumatic compression in addition to a standardized exercise program. The intervention will be delivered over a 3-week period (5 sessions\u002Fweek, 15 sessions in total). Combined contrast therapy will integrate alternating hot and cold thermal therapy with intermittent pneumatic compression. The standardized exercise program will include supervised range-of-motion, stretching, and upper extremity mobility exercises targeting the wrist and hand.",[13],"Device: Combined Contrast Therapy with Intermittent Compression",{"label":15,"type":16,"description":17,"interventionNames":18},"Whirlpool Therapy","ACTIVE_COMPARATOR","Participants in this group will receive whirlpool therapy along with a standardized exercise program. The intervention will be administered over a 3-week period, 5 sessions per week, for a total of 15 sessions.\n\nWhirlpool therapy will be applied by immersing the affected hand and wrist in circulating water maintained at 40 °C, providing both thermal and mechanical stimulation.\n\nThe standardized exercise program will include supervised range-of-motion, stretching, and upper extremity mobility exercises targeting the wrist and hand.",[19],"Device: Whirlpool Therapy",[21,28],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","This non-invasive intervention will be delivered using the Game Ready MED4 Elite device, which integrates thermal therapy (hot-cold) with intermittent pneumatic compression (IPC). The device is capable of simultaneously providing contrast therapy and intermittent pneumatic compression and is widely used in upper and lower extremity rehabilitation.\n\nRapid Contrast Therapy Protocol:\n\nHeat application: Applied at 39 °C for 3 minutes Cold application: Applied at 15 °C for 1 minute, with mild compression during the cold phase Cycle duration: The heat-cold cycle will be repeated continuously for a total of 15 minutes",[9],[26,27],"Game Ready System","Cold and Compression Therapy",{"type":22,"name":15,"description":29,"armGroupLabels":30,"otherNames":31},"Whirlpool therapy is a hydrotherapy modality used to enhance circulation in the upper extremity, reduce muscle spasm, alleviate pain, and facilitate edema resolution. In this study, a Technomex® whirlpool device will be used for hydrotherapy applications. The water temperature will be set at 40 °C and continuously monitored with a thermometer.\n\nThe device motor will generate a circular turbulent water flow. The patient's hand and wrist will be positioned comfortably in the tank without compromising circulation.\n\nThe duration of each session will be 15 minutes.",[15],[32,33],"Hydrotherapy","Technomex Whirlpool Device",[35],{"name":36,"affiliation":5,"role":37},"Gizem Suna Tuncer, MD, Specialist Physician","PRINCIPAL_INVESTIGATOR",[39],{"name":36,"role":40,"phone":41,"phoneExt":42,"email":43},"CONTACT","+905347953185",null,"sunagizem05@gmail.com",[45],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":42,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Etlik City Hospital, Department of Physical Medicine and Rehabilitation","RECRUITING","Ankara","Yenimahalle","06370","Turkey (Türkiye)",{"type":53,"coordinates":54},"Point",[55,56],32.85427,39.91987,{"lat":56,"lon":55},[59],{"name":60,"role":40,"phone":41,"phoneExt":42,"email":43},"Gizem Suna Tuncer, M.D",{"type":37,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":42,"oldOrganization":42},"Gizem Suna Tuncer","Principal Investigator, Physical Medicine and Rehabilitation Specialist","100650195","crps-hand-contrast--compression-vs-whirlpool-100650195",false,"NCT07744269","CRPS-Hand: Contrast + Compression vs Whirlpool","Combined Contrast Therapy and Intermittent Compression vs Whirlpool Therapy in Post-Traumatic Hand and Wrist CRPS: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients diagnosed with Complex Regional Pain Syndrome Type 1 (CRPS-I) according to the Budapest Criteria\n* Age between 18 and 80 years\n* CRPS developed following upper extremity trauma (e.g., hand or wrist fracture, soft tissue injury)\n* Symptom duration less than 3 months (subacute stage)\n* Ability and willingness to provide written informed consent and voluntarily participate in the study\n\nExclusion Criteria:\n\n* Patients diagnosed with Complex Regional Pain Syndrome Type 2 (CRPS-II) or with evidence of peripheral nerve injury\n* History of peripheral neuropathy, Raynaud's phenomenon, or vascular circulation disorders\n* Presence of impaired skin integrity, open wounds, infection, or dermatological disease in the affected area\n* History of cold or heat intolerance, cold urticaria, or hypersensitivity to thermal modalities\n* Active infection or severe edema in the affected extremity\n* Presence of serious systemic diseases (cardiovascular, pulmonary, renal, or neurological)\n* Receipt of similar physical therapy or modality-based treatment within the past 3 months","ALL","18 Years","80 Years",{"count":75,"type":76},50,"ESTIMATED","INTERVENTIONAL",[79],"NA","This randomized controlled trial aims to evaluate and compare the effectiveness of combined contrast therapy with intermittent compression and whirlpool therapy in patients with post-traumatic CRPS-I of the hand and wrist, using objective outcome measures of pain, edema, and functional status.",[82],"Complex Regional Pain Syndrome I (CRPS I)",[84,85,15,86,87],"Contrast Therapy","Intermittent Pneumatic Compression","Complex Regional Pain Syndrome","Hand Rehabilitation","2026-08-01",{"date":90,"type":91},"2026-08-04","ACTUAL",{"date":93,"type":91},"2026-05-01",{"date":95,"type":76},"2027-07-30",{"name":5,"class":6},1]