[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590711":3},{"organization":4,"outcomesModule":7,"designInfo":22,"detailedDescription":25,"studyPopulation":26,"armGroups":21,"interventions":21,"overallOfficials":21,"centralContacts":21,"locations":27,"responsibleParty":439,"collaborators":21,"id":441,"slug":442,"hasResults":443,"nctId":444,"briefTitle":445,"officialTitle":445,"acronym":21,"eligibilityCriteria":446,"healthyVolunteers":443,"sex":447,"minAge":448,"maxAge":21,"enrollmentInfo":449,"targetDuration":21,"studyType":452,"phases":21,"briefSummary":453,"conditions":454,"keywords":21,"overallStatus":30,"whyStopped":21,"lastUpdateSubmitDate":456,"lastUpdatePostDateStruct":457,"startDateStruct":460,"completionDateStruct":462,"leadSponsor":464,"locationsCount":465},{"fullName":5,"class":6},"The European Forum for Research and Education in Allergy and Airway Diseases","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":16,"otherOutcomes":21},[9,13],{"measure":10,"description":11,"timeFrame":12},"Validation of a new questionnaire","Validation of a questionnaire based on similar questionnaires already approved for use in other airway diseases. The aim to measure the current perceived status of a patient with chronic rhinosinusitis in terms of control and severity.\n\nA new questionnaire will be tested and compared with current tools. For this purpose, a set of questionnaires has been developed including the EPOS criteria for chronic rhinosinusitis, the SNOT-22, the patient global assessment tool and the VAS scores, among others.\n\nAll these questionnaires will be completed by the patient at visit 1 and the results will be analysed once the recruitment target of 1,000 patients has been reached.\n\nNo second patient participation is required.","Through study completion, an average of 6 months",{"measure":14,"description":15,"timeFrame":12},"Evaluation of the results","Evaluation of the results of this questionnaire in comparison with other tools currently available.\n\nOnce the target of recruiting 1000 patients has been reached, the results will be statistically analysed.\n\nParallels will be drawn between the responses obtained by the usual means and those captured in the questionnaires to be validated.\n\nIt is expected that, in all cases, the degree of control and severity represented in the questionnaires to be validated will conform to the EPOS criteria and to the results of the questionnaires usually used.\n\nThe results will be compared for each of the new questionnaires in general and separately by language.\n\nThe ultimate goal is to validate what will become the diagnostic gold standard for chronic rhinosinusitis.",[17,19],{"measure":10,"description":18,"timeFrame":12},"Validation of a questionnaire based on feedback collected from patients with CRS where they expressed which are the symptoms that most afflict them or are most present, related to their disease. The aim to measure the current perceived status of a patient with chronic rhinosinusitis in terms of control and severity.\n\nA new questionnaire will be tested and compared with current tools. For this purpose, a set of questionnaires has been developed including the EPOS criteria for chronic rhinosinusitis, the SNOT-22, the patient global assessment tool and the VAS scores, among others.\n\nAll these questionnaires will be completed by the patient at visit 1 and the results will be analysed once the recruitment target of 1,000 patients has been reached.\n\nNo second patient participation is required.",{"measure":14,"description":20,"timeFrame":12},"Evaluation of the results of this questionnaire in comparison with other tools currently available.\n\nOnce the target of recruiting 1000 patients has been reached, the results will be statistically analysed.\n\nParallels will be drawn between the responses obtained by the usual means and those captured in the questionnaires to be validated.\n\nIt is expected that, in all cases, the degree of control and severity represented in the questionnaires to be validated will conform to the EPOS criteria and to the results of the questionnaires usually used.",null,{"allocation":21,"interventionModel":21,"interventionModelDescription":21,"primaryPurpose":21,"observationalModel":23,"timePerspective":24,"maskingInfo":21},"CASE_CONTROL","PROSPECTIVE","The objectives of this study are as follows:\n\n* Validation of two new questionnaires with the aim of measuring the current perceived condition of a patient with chronic rhinosinusitis in terms of control and severity.\n* Validation of these questionnaires in routine medical settings.\n* Evaluation of the results of these questionnaires in comparison with other tools currently available.","Adult patients, capable of giving consent, with certified CRS and no recent sinus surgery",[28,48,63,78,93,108,123,139,153,167,181,193,207,219,233,247,259,273,287,301,313,322,334,343,352,361,373,382,391,403,415,427],{"facility":29,"status":30,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"UCLA Santa Monica Medical Center","RECRUITING","Santa Monica","California","90401","United States","US",{"type":37,"coordinates":38},"Point",[39,40],-118.49138,34.01949,{"lat":40,"lon":39},[43],{"name":44,"role":45,"phone":46,"phoneExt":21,"email":47},"Jivianne Lee","CONTACT","+1 310-825-9111","JTLee@mednet.ucla.edu",{"facility":49,"status":30,"city":50,"state":51,"zip":52,"country":34,"countryCode":35,"cosmosGeoPoint":53,"geoPoint":57,"contacts":58},"Northwestern University Feinberg School of Medicine","Chicago","Illinois","60208",{"type":37,"coordinates":54},[55,56],-87.65005,41.85003,{"lat":56,"lon":55},[59],{"name":60,"role":45,"phone":61,"phoneExt":21,"email":62},"Anju Peters","+1 312-503-8194","anjupeters@northwestern.edu",{"facility":64,"status":30,"city":65,"state":66,"zip":67,"country":34,"countryCode":35,"cosmosGeoPoint":68,"geoPoint":72,"contacts":73},"Brigham Sinus Center at Brigham and Women's Hospital","Boston","Massachusetts","02115",{"type":37,"coordinates":69},[70,71],-71.05977,42.35843,{"lat":71,"lon":70},[74],{"name":75,"role":45,"phone":76,"phoneExt":21,"email":77},"Stella Lee","+1(617) 525-6500","slee192@bwh.harvard.edu",{"facility":79,"status":30,"city":80,"state":81,"zip":82,"country":34,"countryCode":35,"cosmosGeoPoint":83,"geoPoint":87,"contacts":88},"Thomas Jefferson University Hospital","Philadelphia","Pennsylvania","19107",{"type":37,"coordinates":84},[85,86],-75.16362,39.95238,{"lat":86,"lon":85},[89],{"name":90,"role":45,"phone":91,"phoneExt":21,"email":92},"Elina Toskala","+1 215-955-6000","Elina.Toskala@jefferson.edu",{"facility":94,"status":30,"city":95,"state":96,"zip":97,"country":34,"countryCode":35,"cosmosGeoPoint":98,"geoPoint":102,"contacts":103},"Eastern Virginia Medical School","Virginia City","Virginia","23507",{"type":37,"coordinates":99},[100,101],-82.34487,36.91844,{"lat":101,"lon":100},[104],{"name":105,"role":45,"phone":106,"phoneExt":21,"email":107},"Joseph Han","+1 757-446-5600","hanjk@evms.edu",{"facility":109,"status":110,"city":111,"state":21,"zip":21,"country":112,"countryCode":113,"cosmosGeoPoint":114,"geoPoint":118,"contacts":119},"UZ Gent","NOT_YET_RECRUITING","Ghent","Belgium","BE",{"type":37,"coordinates":115},[116,117],3.71667,51.05,{"lat":117,"lon":116},[120],{"name":121,"role":45,"phone":21,"phoneExt":21,"email":122},"Philippe Gevaert","philippe.gevaert@ugent.be",{"facility":124,"status":30,"city":125,"state":21,"zip":21,"country":112,"countryCode":113,"cosmosGeoPoint":126,"geoPoint":130,"contacts":131},"UZ Leuven","Leuven",{"type":37,"coordinates":127},[128,129],4.70093,50.87959,{"lat":129,"lon":128},[132,136],{"name":133,"role":45,"phone":134,"phoneExt":21,"email":135},"Peter Hellings","+32 16 33 23 40","peter.hellings@kuleuven.be",{"name":137,"role":45,"phone":21,"phoneExt":21,"email":138},"Diego Conti","diego.conti@kuleuven.be",{"facility":140,"status":30,"city":141,"state":21,"zip":21,"country":142,"countryCode":143,"cosmosGeoPoint":144,"geoPoint":148,"contacts":149},"St. Michael's Hospital","Toronto","Canada","CA",{"type":37,"coordinates":145},[146,147],-79.39864,43.70643,{"lat":147,"lon":146},[150],{"name":151,"role":45,"phone":21,"phoneExt":21,"email":152},"Yvonne Chan","y.chan@utoronto.ca",{"facility":154,"status":30,"city":155,"state":21,"zip":21,"country":156,"countryCode":157,"cosmosGeoPoint":158,"geoPoint":162,"contacts":163},"Univ of Copenhagen","Copenhagen","Denmark","DK",{"type":37,"coordinates":159},[160,161],12.56553,55.67594,{"lat":161,"lon":160},[164],{"name":165,"role":45,"phone":21,"phoneExt":21,"email":166},"Vibeke Backer","backer@dadlnet.dk",{"facility":168,"status":110,"city":169,"state":21,"zip":21,"country":170,"countryCode":171,"cosmosGeoPoint":172,"geoPoint":176,"contacts":177},"HNO-Klinik, Universitätsklinikum Düsseldorf","Düsseldorf","Germany","DE",{"type":37,"coordinates":173},[174,175],6.77927,51.22319,{"lat":175,"lon":174},[178],{"name":179,"role":45,"phone":21,"phoneExt":21,"email":180},"Martin Wagenmann","martin.wagenmann@hhu.de",{"facility":182,"status":110,"city":183,"state":21,"zip":21,"country":170,"countryCode":171,"cosmosGeoPoint":184,"geoPoint":188,"contacts":189},"Univ Munich","Munich",{"type":37,"coordinates":185},[186,187],11.57549,48.13743,{"lat":187,"lon":186},[190],{"name":191,"role":45,"phone":21,"phoneExt":21,"email":192},"Adam Chaker","adam.chaker@tum.de",{"facility":194,"status":30,"city":195,"state":21,"zip":21,"country":196,"countryCode":197,"cosmosGeoPoint":198,"geoPoint":202,"contacts":203},"University General Hospital of Heraklion","Heraklion","Greece","GR",{"type":37,"coordinates":199},[200,201],25.14341,35.32787,{"lat":201,"lon":200},[204],{"name":205,"role":45,"phone":21,"phoneExt":21,"email":206},"Emmanuel Prokopakis","eprokopakis@gmail.com",{"facility":208,"status":30,"city":209,"state":21,"zip":21,"country":196,"countryCode":197,"cosmosGeoPoint":210,"geoPoint":214,"contacts":215},"U. Aristotle","Thessaloniki",{"type":37,"coordinates":211},[212,213],22.93493,40.64072,{"lat":213,"lon":212},[216],{"name":217,"role":45,"phone":21,"phoneExt":21,"email":218},"Ioannis Konstantinidis","janconst@otenet.gr",{"facility":220,"status":30,"city":221,"state":21,"zip":21,"country":222,"countryCode":223,"cosmosGeoPoint":224,"geoPoint":228,"contacts":229},"Univ Hospital Roma","Roma","Italy","IT",{"type":37,"coordinates":225},[226,227],11.10642,44.99364,{"lat":227,"lon":226},[230],{"name":231,"role":45,"phone":21,"phoneExt":21,"email":232},"Eugenio De Corso","eugenio.decorso@policlinicogemelli.it",{"facility":234,"status":110,"city":235,"state":21,"zip":21,"country":236,"countryCode":237,"cosmosGeoPoint":238,"geoPoint":242,"contacts":243},"Univ Amsterdam","Amsterdam","Netherlands","NL",{"type":37,"coordinates":239},[240,241],4.88969,52.37403,{"lat":241,"lon":240},[244],{"name":245,"role":45,"phone":21,"phoneExt":21,"email":246},"Wytske Fokkens","w.j.fokkens@amsterdamumc.nl",{"facility":248,"status":30,"city":249,"state":21,"zip":21,"country":236,"countryCode":237,"cosmosGeoPoint":250,"geoPoint":254,"contacts":255},"Alrijne Zorggroep","Leiden",{"type":37,"coordinates":251},[252,253],4.49306,52.15833,{"lat":253,"lon":252},[256],{"name":257,"role":45,"phone":21,"phoneExt":21,"email":258},"Marjolein Cornet","mecornet@alrijne.nl",{"facility":260,"status":30,"city":261,"state":21,"zip":21,"country":262,"countryCode":263,"cosmosGeoPoint":264,"geoPoint":268,"contacts":269},"University of Oradea","Oradea","Romania","RO",{"type":37,"coordinates":265},[266,267],21.91833,47.0458,{"lat":267,"lon":266},[270],{"name":271,"role":45,"phone":21,"phoneExt":21,"email":272},"Felicia Manole","manole.felicia@gmail.com",{"facility":274,"status":30,"city":275,"state":21,"zip":21,"country":276,"countryCode":277,"cosmosGeoPoint":278,"geoPoint":282,"contacts":283},"Ahmed Alkhadi Hospital","Durban","South Africa","ZA",{"type":37,"coordinates":279},[280,281],31.0292,-29.8579,{"lat":281,"lon":280},[284],{"name":285,"role":45,"phone":21,"phoneExt":21,"email":286},"Devesh Ramdhani","dr.d.ramdhani@gmail.com",{"facility":288,"status":30,"city":289,"state":21,"zip":21,"country":290,"countryCode":291,"cosmosGeoPoint":292,"geoPoint":296,"contacts":297},"Hospital Clínico Universitario de Compostela","A Coruña","Spain","ES",{"type":37,"coordinates":293},[294,295],-8.396,43.37135,{"lat":295,"lon":294},[298],{"name":299,"role":45,"phone":21,"phoneExt":21,"email":300},"Christian Calvo Henriquez","christian.calvo.henriquez@gmail.com",{"facility":302,"status":30,"city":303,"state":21,"zip":21,"country":290,"countryCode":291,"cosmosGeoPoint":304,"geoPoint":308,"contacts":309},"Hospital Clinic Barcelona","Barcelona",{"type":37,"coordinates":305},[306,307],2.15899,41.38879,{"lat":307,"lon":306},[310],{"name":311,"role":45,"phone":21,"phoneExt":21,"email":312},"Isam Alobid","isamalobid@gmail.com",{"facility":314,"status":30,"city":303,"state":21,"zip":21,"country":290,"countryCode":291,"cosmosGeoPoint":315,"geoPoint":317,"contacts":318},"Hospital de la Santa Creu i Sant Pau",{"type":37,"coordinates":316},[306,307],{"lat":307,"lon":306},[319],{"name":320,"role":45,"phone":21,"phoneExt":21,"email":321},"Juan Ramon Gras Cabrerizo","JGras@santpau.cat",{"facility":323,"status":30,"city":324,"state":21,"zip":21,"country":290,"countryCode":291,"cosmosGeoPoint":325,"geoPoint":329,"contacts":330},"Hospital de La Línea de La Concepción","Cadiz",{"type":37,"coordinates":326},[327,328],-6.2891,36.52672,{"lat":328,"lon":327},[331],{"name":332,"role":45,"phone":21,"phoneExt":21,"email":333},"Eduardo Correa","ecorreaorl@gmail.com",{"facility":335,"status":30,"city":324,"state":21,"zip":21,"country":290,"countryCode":291,"cosmosGeoPoint":336,"geoPoint":338,"contacts":339},"Hospital Universitario Jerez de La Frontera",{"type":37,"coordinates":337},[327,328],{"lat":328,"lon":327},[340],{"name":341,"role":45,"phone":21,"phoneExt":21,"email":342},"Alfonso Del Cuvillo Bernal","dr.cuvillo@gmail.com",{"facility":344,"status":30,"city":324,"state":21,"zip":21,"country":290,"countryCode":291,"cosmosGeoPoint":345,"geoPoint":347,"contacts":348},"Hospital Universitario Puerta del Mar",{"type":37,"coordinates":346},[327,328],{"lat":328,"lon":327},[349],{"name":350,"role":45,"phone":21,"phoneExt":21,"email":351},"Andrés Caballero García","handdres@gmail.com",{"facility":353,"status":30,"city":324,"state":21,"zip":21,"country":290,"countryCode":291,"cosmosGeoPoint":354,"geoPoint":356,"contacts":357},"Hospital Universitario Puerto Real",{"type":37,"coordinates":355},[327,328],{"lat":328,"lon":327},[358],{"name":359,"role":45,"phone":21,"phoneExt":21,"email":360},"Carlos Almagro Ordoñez","Almagro.86@hotmail.com",{"facility":362,"status":30,"city":363,"state":21,"zip":21,"country":290,"countryCode":291,"cosmosGeoPoint":364,"geoPoint":368,"contacts":369},"Hospital Universitario Fuenlabrada","Madrid",{"type":37,"coordinates":365},[366,367],-3.70256,40.4165,{"lat":367,"lon":366},[370],{"name":371,"role":45,"phone":21,"phoneExt":21,"email":372},"Ithzel María Villareal","imvillarrealp@gmail.com",{"facility":374,"status":30,"city":363,"state":21,"zip":21,"country":290,"countryCode":291,"cosmosGeoPoint":375,"geoPoint":377,"contacts":378},"Hospital Universitario Infanta Elena, Madrid y Hospital Universitario Fundación Jiménez Díaz",{"type":37,"coordinates":376},[366,367],{"lat":367,"lon":366},[379],{"name":380,"role":45,"phone":21,"phoneExt":21,"email":381},"Alvaro Sanchez Barrueco","alvaro.sanchez@quironsalud.es",{"facility":383,"status":30,"city":363,"state":21,"zip":21,"country":290,"countryCode":291,"cosmosGeoPoint":384,"geoPoint":386,"contacts":387},"Hospital Universitario Ramón y Cajal",{"type":37,"coordinates":385},[366,367],{"lat":367,"lon":366},[388],{"name":389,"role":45,"phone":21,"phoneExt":21,"email":390},"Alfonso Santamaría Gadea","asantamariagadea@gmail.com",{"facility":392,"status":30,"city":393,"state":21,"zip":21,"country":290,"countryCode":291,"cosmosGeoPoint":394,"geoPoint":398,"contacts":399},"Hospital del Bierzo","Ponferrada",{"type":37,"coordinates":395},[396,397],-6.59619,42.54664,{"lat":397,"lon":396},[400],{"name":401,"role":45,"phone":21,"phoneExt":21,"email":402},"Xenia Mota","mota.xenia@gmail.com",{"facility":404,"status":30,"city":405,"state":21,"zip":21,"country":290,"countryCode":291,"cosmosGeoPoint":406,"geoPoint":410,"contacts":411},"Hospital Universitario Marqués de Valdecilla","Santander",{"type":37,"coordinates":407},[408,409],-3.80493,43.46589,{"lat":409,"lon":408},[412],{"name":413,"role":45,"phone":21,"phoneExt":21,"email":414},"David Lobo Duro","dlobo28@gmail.com",{"facility":416,"status":30,"city":417,"state":21,"zip":21,"country":290,"countryCode":291,"cosmosGeoPoint":418,"geoPoint":422,"contacts":423},"Hospital Universitario Virgen Macarena","Seville",{"type":37,"coordinates":419},[420,421],-5.97317,37.38283,{"lat":421,"lon":420},[424],{"name":425,"role":45,"phone":21,"phoneExt":21,"email":426},"Ramón Moreno Luna","ramoluorl@gmail.com",{"facility":428,"status":30,"city":429,"state":21,"zip":21,"country":290,"countryCode":291,"cosmosGeoPoint":430,"geoPoint":434,"contacts":435},"Hospital General Universitario de Valencia","Valencia",{"type":37,"coordinates":431},[432,433],-0.37966,39.47391,{"lat":433,"lon":432},[436],{"name":437,"role":45,"phone":21,"phoneExt":21,"email":438},"Ainhoa García Lliberós de Miguel","ainhoa.glliberos@gmail.com",{"type":440,"investigatorFullName":21,"investigatorTitle":21,"investigatorAffiliation":21,"oldNameTitle":21,"oldOrganization":21},"SPONSOR","100590711","crs-questionnaire-validation-project-100590711",false,"NCT06970977","CRS Questionnaire Validation Project","Inclusion Criteria:\n\n* Patient capable of giving informed consent\n* Diagnosis of chronic rhinosinusitis with or without nasal polyposis according to the EPOS guidelines\n* No recent sinus surgery (within the last three months)\n\nExclusion Criteria:\n\n* Not capable of giving informed consent\n* No CRS\n* Recent sinus surgery (within the last three months)","ALL","18 Years",{"count":450,"type":451},1000,"ESTIMATED","OBSERVATIONAL","The 'CRS validation project' consists of a joint effort of 32 medical centers in Europe, the USA, and South Africa to carry out the validation of 2 novel questionnaires designated to measure self-perceived severity and control of Chronic Rhinosinusitis (with or without nasal polyps).\n\nThis study will validate translated versions of the same set of questionnaires simultaneously in the centers involved after recruiting a total of 1000 patients, while data collection, statistical analysis, and creation of the study report will be carried out by the statistical department of the University of Leuven.\n\nPatients will be recruited from the regular ENT practice of their hospital to minimize the complexity of the study.",[455],"Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps","2026-09-08",{"date":458,"type":459},"2026-09-09","ACTUAL",{"date":461,"type":459},"2024-09-01",{"date":463,"type":451},"2027-09-30",{"name":5,"class":6},32]