[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100652191":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":54,"collaborators":25,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":60,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":25,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":39,"whyStopped":25,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Medipol University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group DSG","ACTIVE_COMPARATOR","Patients will receive an ultrasound-guided Deep Subgluteal Block using a total of 30 mL of 0.25% bupivacaine (15 mL administered beneath the gluteus minimus muscle and 15 mL beneath the gluteus medius muscle).",[13],"Drug: 0.25% Bupivacaine for Deep Subgluteal Block",{"label":15,"type":10,"description":16,"interventionNames":17},"Group PENG+LCFN","Patients will receive an ultrasound-guided Pericapsular Nerve Group (PENG) block combined with a Lateral Femoral Cutaneous Nerve (LFCN) block. The PENG block will be performed with 20 mL of 0.25% bupivacaine. The LFCN block will be performed using a 10 mL volume consisting of 5 mL of 0.25% bupivacaine diluted with 5 mL of normal saline (0.9% NaCl), resulting in a final local anesthetic concentration of 0.125% bupivacaine at the LFCN site.",[18],"Drug: 0.25% and 0.125% Bupivacaine for PENG+LFCN Block",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","0.25% Bupivacaine for Deep Subgluteal Block","Ultrasound-guided regional anesthesia. Patients receive 30 mL of 0.25% bupivacaine, divided as 15 mL beneath the gluteus minimus muscle and 15 mL beneath the gluteus medius muscle.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"0.25% and 0.125% Bupivacaine for PENG+LFCN Block","Ultrasound-guided combination regional anesthesia. Patients receive a PENG block with 20 mL of 0.25% bupivacaine, combined with an LFCN block using 10 mL of 0.125% bupivacaine (5 mL of 0.25% bupivacaine diluted with 5 mL of 0.9% normal saline).",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Yunus O Atalay, MD, Prof., DESAIC","CONTACT","+90 212 453 4800","yoatalay@medipol.edu.tr",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":25,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Medipol Mega University Hospital","RECRUITING","Istanbul","Bagcilar","34214","Turkey (Türkiye)",{"type":45,"coordinates":46},"Point",[47,48],28.94966,41.01384,{"lat":48,"lon":47},[51],{"name":52,"role":33,"phone":34,"phoneExt":25,"email":53},"Haci Ahmet Alici, MD, Prof.","haalici@medipol.edu.tr",{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Yunus Oktay Atalay","Professor of Anesthesiology","100652191","deep-subgluteal-block-vs-peng-combined-with-lfcn-block-for-analgesia-after-hip-arthroplasty-100652191",false,"NCT07770932","Deep Subgluteal Block vs PENG Combined With LFCN Block for Analgesia After Hip Arthroplasty","Comparison of Deep Subgluteal Block and Pericapsular Nerve Group Block Combined With Lateral Femoral Cutaneous Nerve Block for Postoperative Analgesia After Hip Arthroplasty: A Randomized Prospective Study","DSG-PENG","Inclusion Criteria:\n\n* Patients scheduled for elective total or partial hip arthroplasty under general anesthesia\n* American Society of Anesthesiologists (ASA) physical status I-III\n* Aged between 18 and 80 years\n* Able to understand the study procedures, give voluntary written informed consent, and operate a patient-controlled analgesia (PCA) device\n\nExclusion Criteria:\n\n* Patient refusal or inability to provide informed consent\n* Pre-existing peripheral neuropathy, cognitive impairment, or psychiatric disorders\n* History of significant severe renal or hepatic failure\n* Allergy or hypersensitivity to amide-type local anesthetics or opioids\n* Infection, severe anatomic distortion, or previous surgery at the proposed block injection sites\n* History of substance abuse or chronic opioid use (defined as daily opioid use for \\> 3 months prior to surgery)","ALL","18 Years","80 Years",{"count":70,"type":71},60,"ESTIMATED","INTERVENTIONAL",[74],"NA","This randomized, prospective study aims to compare the clinical efficacy of ultrasound-guided Deep Subgluteal Block (DSGB) versus Pericapsular Nerve Group (PENG) block combined with Lateral Femoral Cutaneous Nerve (LFCN) block for postoperative analgesia management in patients undergoing hip arthroplasty.\n\nA total of 60 patients scheduled for hip arthroplasty under general anesthesia will be randomly allocated into two equal groups of 30: Group DSG and Group PENG+LFCN. Total local anesthetic volume (30 mL) and active drug dose (75 mg bupivacaine) will be standardized across both groups to ensure rigorous blinding and high methodological quality.\n\nThe primary outcome of the study is to compare total postoperative opioid (fentanyl) consumption within the first 24 hours. Secondary outcomes include postoperative pain scores evaluated via the Numerical Rating Scale (NRS) at rest and during movement, the presence and degree of quadriceps motor block, and opioid-related adverse effects (e.g., nausea, vomiting, pruritus).",[77],"Postoperative Pain",[79],"Deep Subgluteal Block PENG Block Lateral Femoral Cutaneous Nerve Block Hip Arthroplasty Nerve Block Opioid Consumption","2026-08-13",{"date":82,"type":83},"2026-08-18","ACTUAL",{"date":85,"type":71},"2026-08-01",{"date":87,"type":71},"2027-01-30",{"name":5,"class":6},1]