[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100659153":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":21,"studyPopulation":13,"armGroups":22,"interventions":33,"overallOfficials":38,"centralContacts":13,"locations":43,"responsibleParty":57,"collaborators":60,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":79,"sex":80,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":13,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":93,"overallStatus":101,"whyStopped":13,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"Universite du Quebec en Outaouais","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"the Vaccine Hesitancy Scale (VHS)","Vaccine hesitancy will be assessed using the Vaccine Hesitancy Scale (VHS). The total score ranges from 10 to 50, with higher scores indicating greater vaccine hesitancy. Change from baseline will be compared between the intervention and control groups across follow-up assessments.","Baseline (T0), immediately post-intervention (Ti), 3 months, and 6 months",null,{"allocation":15,"interventionModel":16,"interventionModelDescription":17,"primaryPurpose":6,"observationalModel":13,"timePerspective":13,"maskingInfo":18},"RANDOMIZED","PARALLEL","Participants will be randomized 1:1 to either the digital educational intervention + immunization training of INSPQ or the control condition (the immunization training of INSPQ only). They will followed for six months (T 3 months and T 6 months)",{"masking":19,"maskingDescription":20,"whoMasked":13},"NONE","The trial will be open label. Statistical analyses will be conducted with treatment groups coded until completion of the primary analyses.","Vaccine hesitancy can influence vaccine acceptance and communication between healthcare professionals and the public. Registered nurses have an important role in vaccination, including providing information, addressing concerns, and recommending vaccination.\n\nThis study will evaluate a digital educational intervention designed to strengthen knowledge related to vaccines, confidence, and communication among registered nurses in Quebec. The intervention will complement existing immunization training of INSPQ. It will integrate content on immunology, epidemiology, motivational interviewing, vaccine communication, and responses to vaccine misinformation.\n\nThe study will use a randomized controlled design with two parallel groups. Participants will be randomly assigned to the digital educational intervention + immunization training of INSPQ or the control condition (the immunization training of INSPQ, only). The intervention will be evaluated using measurements collected before and after the intervention and during follow-up (3 months and 6 months).\n\nThe primary focus will be the effect of the intervention on vaccine hesitancy of nurses. Secondary aims will include vaccine recommendation practices, immunological and epidemiological knowledge, and vaccine communication competencies.\n\nQuestionnaires will also examine psychosocial determinants of vaccination attitudes and behaviors. The pilot phase preceding the randomized trial will support refinement of the intervention, questionnaires, study procedures, and measurement instruments.\n\nThe study aims to generate evidence on whether digital education can strengthen nurses' vaccine-related competencies and support their communication with patients and the public.",[23,29],{"label":24,"type":25,"description":26,"interventionNames":27},"Digital educational intervention + immunization training of INSPQ","EXPERIMENTAL","Registered nurses assigned to this arm will receive the digital educational intervention in addition to the existing immunization training provided by the INSPQ. The digital intervention will include immunology, epidemiology, motivational interviewing, vaccine communication, and strategies for responding to vaccine misinformation.",[28],"Other: Digital educational intervention",{"label":30,"type":25,"description":31,"interventionNames":32},"Control","Registered nurses assigned to this arm will receive the existing immunization training provided by the INSPQ without the additional digital educational intervention.",[28],[34],{"type":6,"name":35,"description":36,"armGroupLabels":37,"otherNames":13},"Digital educational intervention","The VaxNurse digital educational intervention is designed for registered nurses. It includes educational content on immunology and epidemiology, motivational interviewing, vaccine communication, and strategies for responding to vaccine misinformation. The intervention aims to reduce vaccine hesitancy and strengthen knowledge related to vaccine, confidence, communication skills, and recommendation practices. It complements existing immunization training provided by the INSPQ.",[30,24],[39],{"name":40,"affiliation":41,"role":42},"Philippe Corsenac, Ph.D.","Université du Québec en Outaouais","PRINCIPAL_INVESTIGATOR",[44],{"facility":41,"status":13,"city":45,"state":13,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Saint-Jérôme","J7Z 0B7","Canada","CA",{"type":50,"coordinates":51},"Point",[52,53],-74.00365,45.78036,{"lat":53,"lon":52},[56],{"name":40,"role":42,"phone":13,"phoneExt":13,"email":13},{"type":42,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":13,"oldOrganization":13},"Corsenac Philippe","Dr in epidemiology and immunology",[61,63,65,67,69],{"name":62,"class":6},"Ministere de la Sante et des Services Sociaux",{"name":64,"class":6},"McGill University",{"name":66,"class":6},"Angers University",{"name":68,"class":6},"Université Victor Segalen Bordeaux 2",{"name":70,"class":71},"ordre des infirmières et des infirmiers du Québec","UNKNOWN","100659153","development-and-evaluation-of-a-digital-educational-intervention-to-improve-vaccine-confidence-and-communication-among-registered-nurses-protocol-for-a-randomized-controlled-trial-vaxnurse-rct-100659153",false,"NCT07859579","Development and Evaluation of a Digital Educational Intervention to Improve Vaccine Confidence and Communication Among Registered Nurses: Protocol for a Randomized Controlled Trial (VaxNurse-RCT).","VaxNurse-RCT","Inclusion Criteria:\n\n* Registered nurse authorized to practice in Quebec.\n* Aged 18 years or older.\n* Able to provide informed consent.\n* Able to complete the study questionnaires in French or English and digital educational intervention in French.\n\nExclusion Criteria:\n\n* Not currently authorized to practice as a registered nurse in Quebec.\n* Unable to provide informed consent.\n* Previous participation in the VaxNurse pilot study.",true,"ALL","18 Years","62 Years",{"count":84,"type":85},100,"ESTIMATED","INTERVENTIONAL",[88],"NA","Nurses play an important role in providing vaccine information and supporting informed vaccination decisions.\n\nThis study will evaluate a digital educational intervention designed for registered nurses in Quebec. The intervention will provide education about vaccination, including immunology, epidemiology, vaccine communication, motivational interviewing, and responding to vaccine misinformation.\n\nRegistered nurses will be randomly assigned to either the intervention group or a control group. The study will examine whether the intervention improves vaccine confidence and vaccine communication compared with the control group.\n\nParticipants will complete questionnaires before and after the intervention, with follow-up assessments at 3 and 6 months. The study will assess vaccine hesitancy and changes in vaccine-related knowledge, communication skills, and vaccination recommendation practices.\n\nThe findings will help determine whether a digital educational intervention can support nurses in their vaccine-related communication and professional practice.",[91,92],"Vaccine Hesitancy","Vaccine Acceptance",[94,95,96,97,98,99,100],"vaccination","Registered nurses","vaccine communication","motivational onterviewing","digital education","vaccine misinformation","health promotion","NOT_YET_RECRUITING","2026-09-30",{"date":104,"type":105},"2026-10-06","ACTUAL",{"date":107,"type":85},"2027-01-01",{"date":109,"type":85},"2027-12-31",{"name":5,"class":6},1]