[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100653360":3},{"organization":4,"outcomesModule":7,"designInfo":18,"detailedDescription":21,"studyPopulation":22,"armGroups":17,"interventions":17,"overallOfficials":23,"centralContacts":28,"locations":17,"responsibleParty":37,"collaborators":17,"id":41,"slug":42,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":17,"eligibilityCriteria":47,"healthyVolunteers":43,"sex":48,"minAge":49,"maxAge":17,"enrollmentInfo":50,"targetDuration":53,"studyType":54,"phases":17,"briefSummary":55,"conditions":56,"keywords":61,"overallStatus":65,"whyStopped":17,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":17},{"fullName":5,"class":6},"Assiut University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":17},[9],{"measure":10,"description":11,"timeFrame":12},"Diagnostic accuracy of triphasic bone scan and SPECT\u002FCT","Sensitivity, specificity, positive predictive value, and negative predictive value of triphasic bone scintigraphy and SPECT\u002FCT for detecting foot and ankle osteoarthritis, using MRI as the reference standard.","Baseline",[14],{"measure":15,"description":16,"timeFrame":12},"Identification of affected joints","Determination of the specific joints affected by osteoarthritis in the foot and ankle based on SPECT\u002FCT and MRI findings.",null,{"allocation":17,"interventionModel":17,"interventionModelDescription":17,"primaryPurpose":17,"observationalModel":19,"timePerspective":20,"maskingInfo":17},"CASE_ONLY","CROSS_SECTIONAL","Osteoarthritis of the foot and ankle is a significant cause of chronic pain and functional impairment. Conventional radiography has limited sensitivity for early changes, while magnetic resonance imaging (MRI) is considered the reference standard for evaluating cartilage, bone marrow edema, and soft tissue structures.\n\nNuclear medicine techniques provide functional information about bone metabolism. Triphasic bone scan using technetium-99m methylene diphosphonate (99mTc-MDP) assesses perfusion, blood pool, and delayed skeletal uptake. However, planar imaging has limited spatial resolution and anatomical localization in the complex anatomy of the foot and ankle.\n\nHybrid SPECT\u002FCT combines the functional data of SPECT with the precise anatomical localization of CT, improving diagnostic confidence and specificity. This study will evaluate the diagnostic accuracy of triphasic bone scan and SPECT\u002FCT compared with MRI in patients with suspected foot and ankle osteoarthritis.","Adult patients with chronic foot and\u002For ankle pain suspected of osteoarthritis referred to the Nuclear Medicine Unit at Assiut University Hospital who meet the eligibility criteria.",[24],{"name":25,"affiliation":26,"role":27},"Mohamed A Mekawy, prof","assiut","STUDY_CHAIR",[29,34],{"name":30,"role":31,"phone":32,"phoneExt":32,"email":33},"Amira A Ebraheem, resident","CONTACT","01212838177","aaabbb10121999@gmail.com",{"name":25,"role":31,"phone":35,"phoneExt":35,"email":36},"01223196777","M_mekkay51@yahoo.com",{"type":38,"investigatorFullName":39,"investigatorTitle":40,"investigatorAffiliation":5,"oldNameTitle":17,"oldOrganization":17},"PRINCIPAL_INVESTIGATOR","Amira Adel Ebraheem Abdelhameed","Resident","100653360","diagnostic-accuracy-of-triphasic-bone-scan-and-spectct-in-foot-and-ankle-osteoarthritis-100653360",false,"NCT07784257","Diagnostic Accuracy of Triphasic Bone Scan and SPECT\u002FCT in Foot and Ankle Osteoarthritis","Diagnostic Accuracy of Triphasic Bone Scan and SPECT\u002FCT for the Evaluation of Foot and Ankle Osteoarthritis Using MRI as Reference Standard","Inclusion Criteria:\n\nAge ≥ 18 years\n\n* Patients presenting with chronic foot and\u002For ankle pain suspected to be due to osteoarthritis\n* Clinical and\u002For radiographic suspicion of foot or ankle osteoarthritis\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years\n* Previous surgery or joint replacement of the affected foot or ankle\n* Bone tumors or metastatic bone disease\n* Active osteomyelitis or septic arthritis\n* Inflammatory arthropathies (e.g., rheumatoid arthritis, psoriatic arthritis, gout)","ALL","18 Years",{"count":51,"type":52},40,"ESTIMATED","1 Day","OBSERVATIONAL","This cross-sectional study aims to assess the diagnostic accuracy of triphasic bone scintigraphy and SPECT\u002FCT in evaluating foot and ankle osteoarthritis, using magnetic resonance imaging (MRI) as the reference standard, and to determine the affected joints.",[57,58,59,60],"Osteoarthritis","Foot Osteoarthritis","Joint Diseases","Ankle Osteoarthritis",[62,63,64],"SPECT\u002FCT","Triphasic bone scan","Diagnostic accuracy","NOT_YET_RECRUITING","2026-09-01",{"date":68,"type":69},"2026-09-02","ACTUAL",{"date":71,"type":52},"2026-08-20",{"date":73,"type":52},"2028-01-20",{"name":5,"class":6}]