[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100651794":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":24,"locations":10,"responsibleParty":30,"collaborators":10,"id":34,"slug":35,"hasResults":36,"nctId":37,"briefTitle":38,"officialTitle":39,"acronym":10,"eligibilityCriteria":40,"healthyVolunteers":36,"sex":41,"minAge":42,"maxAge":10,"enrollmentInfo":43,"targetDuration":10,"studyType":46,"phases":10,"briefSummary":47,"conditions":48,"keywords":10,"overallStatus":50,"whyStopped":10,"lastUpdateSubmitDate":51,"lastUpdatePostDateStruct":52,"startDateStruct":55,"completionDateStruct":57,"leadSponsor":59,"locationsCount":10},{"fullName":5,"class":6},"Istinye University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients Who Develop Postspinal Hypotension",null,"Patients who develop postspinal hypotension, defined as a decrease in systolic arterial pressure of 25% or more from baseline and\u002For a systolic arterial pressure below 90 mmHg following spinal anesthesia.",[13],"Procedure: Spinal Anesthesia",{"label":15,"type":10,"description":16,"interventionNames":17},"Patients Who Do Not Develop Postspinal Hypotension","Patients who do not develop postspinal hypotension, defined as the absence of a decrease in systolic arterial pressure of 25% or more from baseline and a systolic arterial pressure remaining at or above 90 mmHg following spinal anesthesia.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"PROCEDURE","Spinal Anesthesia","Spinal anesthesia will be administered as part of routine clinical care for elective unilateral inguinal hernia surgery. The study will not modify the anesthetic management or introduce any additional intervention for research purposes. Hemodynamic parameters obtained during routine perioperative monitoring will be recorded to evaluate the development of postspinal hypotension.",[9,15],[25],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"ilke dolğun","CONTACT","5555485632","ilkeser2004@gmail.com",{"type":31,"investigatorFullName":32,"investigatorTitle":33,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","İlke Dolgun","assoc prof","100651794","diastolic-shock-index-for-predicting-postspinal-hypotension-100651794",false,"NCT07765342","Diastolic Shock Index for Predicting Postspinal Hypotension","Comparison of the Diagnostic Performance of the Diastolic Shock Index and Other Shock Indices in Predicting Postspinal Hypotension","Inclusion Criteria:\n\n* Age 50 years or older\n* Scheduled for elective unilateral inguinal hernia surgery\n* Scheduled to undergo surgery under spinal anesthesia\n* American Society of Anesthesiologists physical status I-III\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Refusal to participate in the study\n* Emergency surgery\n* Bilateral inguinal hernia surgery\n* Contraindication to spinal anesthesia\n* Failure of spinal anesthesia or conversion to general anesthesia due to failed spinal block\n* Requirement for additional general anesthesia or deep sedation during surgery\n* Operation duration exceeding 120 minutes\n* Atrial fibrillation, atrial flutter, frequent ventricular ectopy, or other arrhythmias preventing reliable heart rate assessment\n* Presence of a permanent cardiac pacemaker\n* Severe valvular heart disease\n* New York Heart Association class III-IV heart failure\n* Preoperative use of vasopressor or inotropic therapy\n* Severe hepatic failure or end-stage renal disease\n* Neurological disease that may significantly affect autonomic nervous system function\n* Preoperative hemodynamic instability, defined as systolic arterial pressure \\\u003C90 mmHg or \\>180 mmHg, or heart rate \\\u003C50 or \\>120 beats\u002Fmin\n* Missing study data or inability to obtain records in accordance with the study protocol","ALL","50 Years",{"count":44,"type":45},85,"ESTIMATED","OBSERVATIONAL","This prospective observational study aims to evaluate the diagnostic performance of the preoperative Diastolic Shock Index in predicting postspinal hypotension and to compare its performance with other shock indices, including the Shock Index, Modified Shock Index, and Age Shock Index. The study will include patients aged 50 years and older undergoing elective unilateral inguinal hernia surgery under spinal anesthesia. Hemodynamic parameters will be recorded before and after spinal anesthesia as part of routine clinical monitoring. The primary outcome is the development of postspinal hypotension. Secondary outcomes include vasopressor requirement, total ephedrine dose, lowest intraoperative mean arterial pressure, and the diagnostic performance of the evaluated shock indices using receiver operating characteristic curve analysis. No additional intervention beyond routine anesthetic and perioperative care will be performed for study purposes.",[49],"Postspinal Hypotension","NOT_YET_RECRUITING","2026-08-11",{"date":53,"type":54},"2026-08-14","ACTUAL",{"date":56,"type":45},"2026-08-21",{"date":58,"type":45},"2027-03-07",{"name":5,"class":6}]