[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646386":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":18,"responsibleParty":51,"collaborators":10,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":56,"sex":62,"minAge":63,"maxAge":10,"enrollmentInfo":64,"targetDuration":10,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":73,"overallStatus":37,"whyStopped":10,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Scripps Health","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"DELTA Cohort",null,"This is the main cohort in which all participants will be enrolled in. These individuals are older adults admitted to the intensive care unit (ICU) with an expected stay of at least 48 hours. Broadly, individuals cannot have advanced dementia at baseline, have liver cirrhosis or be on any kind of renal replacement therapy.",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Stuti Jaiswal, MD, PhD","CONTACT","858-554-9100","jaiswal.stuti@scrippshealth.org",[19,35],{"facility":20,"status":21,"city":22,"state":23,"zip":24,"country":25,"countryCode":26,"cosmosGeoPoint":27,"geoPoint":32,"contacts":33},"Scripps Green Hospital","NOT_YET_RECRUITING","La Jolla","California","92037","United States","US",{"type":28,"coordinates":29},"Point",[30,31],-117.2742,32.84727,{"lat":31,"lon":30},[34],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},{"facility":36,"status":37,"city":38,"state":23,"zip":39,"country":25,"countryCode":26,"cosmosGeoPoint":40,"geoPoint":44,"contacts":45},"Scripps Memorial La Jolla Hospital","RECRUITING","San Diego","92117",{"type":28,"coordinates":41},[42,43],-117.16472,32.71571,{"lat":43,"lon":42},[46,48,49],{"name":47,"role":15,"phone":16,"phoneExt":10,"email":17},"Stuti J Jaiswal, MD, PhD",{"name":10,"role":15,"phone":10,"phoneExt":10,"email":17},{"name":47,"role":50,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"type":50,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Stuti Jaiswal","Faculty Hospitalist","100646386","digital-and-plasma-biomarkers-in-delirium-100646386",false,"NCT07694206","Digital and Plasma Biomarkers in Delirium","Delirium Evaluation With Longitudinal Tau Assessment","DELTA","Inclusion Criteria:\n\n* Admitted to the intensive care unit\n* Able to consent or have a legally authorized representative consent on their behalf\n* English speaker\n* Expected ICU stay of 48 hours or more\n\nExclusion Criteria:\n\n* Advanced dementia\n* End stage liver disease\n* Renal replacement therapy\n* Structural brain injury, including but not limited to traumatic brain injury, cerebrovascular accident and intracranial hemorrhage,","ALL","65 Years",{"count":65,"type":66},100,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn if there are potential digital and plasma-based biomarkers that could help detect, predict, and prognosticate delirium in older adult patients who are admitted to the intensive care unit (ICU). The main question DELTA aims to answer is:\n\nCan digital biometrics predict and detect delirium in older adult ICU patients? Do biomarkers of neurodegeneration fluctuate in ICU patients in such a way that delrium could potentially be predicted?\n\nParticipants admitted o the ICU will wear a digital device to collect biometric data and will have serial plasma samples collected during ICU admission and patients will be also assessed for delirium daily by study staff.",[70,71,72],"Critical Illness","Delirium in the Intensive Care Unit","Sleep Quality",[74,75,76],"Sleep in the ICU","Delirium in the ICU","Delirium biomarkers","2026-07-02",{"date":79,"type":80},"2026-07-09","ACTUAL",{"date":82,"type":80},"2026-05-28",{"date":84,"type":66},"2027-12-31",{"name":5,"class":6},2]