[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646271":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":52,"collaborators":26,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":26,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":26,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":26,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Azienda Ospedaliero-Universitaria Careggi","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Digital indirect bonding in the upper arch and conventional indirect bonding in the lower arch","EXPERIMENTAL","Participants assigned to this arm will receive digital indirect bonding in the upper arch and conventional indirect bonding in the lower arch.",[13,14],"Device: digital indirect bonding technique","Device: conventional indirect bonding technique",{"label":16,"type":17,"description":18,"interventionNames":19},"Conventional indirect bonding in the upper arch and digital indirect bonding in the lower arch","ACTIVE_COMPARATOR","Participants assigned to this arm will receive conventional indirect bonding in the upper arch and digital indirect bonding in the lower arch.",[13,14],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","digital indirect bonding technique","Fixed orthodontic appliance will be bonded using a digital indirect bonding technique",[16,9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"conventional indirect bonding technique","Fixed orthodontic appliance will be bonded using a conventional indirect bonding technique",[16,9],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Lorenzo Franchi","CONTACT","+390557945602","lorenzo.franchi@unifi.it",[38],{"facility":39,"status":40,"city":41,"state":26,"zip":26,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Orthodontic Clinic, Division of Dentistry, Careggi University Hospital","RECRUITING","Florence","Italy","IT",{"type":45,"coordinates":46},"Point",[47,48],11.24626,43.77925,{"lat":48,"lon":47},[51],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},{"type":53,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100646271","digital-vs-conventional-indirect-bonding-100646271",false,"NCT07692880","Digital vs. Conventional Indirect Bonding.","Comparison of Indirect Bonding of Orthodontic Brackets Using Digital Versus Conventional Technology: A Randomized Controlled Trial on Bonding Time and Bracket Failure","Inclusion Criteria:\n\n* Patients aged 12 to 18 years requiring fixed orthodontic treatment on both upper and lower arches\n* Presence of full permanent dentition, including erupted second molars\n\nExclusion Criteria:\n\n* Presence of dental anomalies in number (supernumerary or missing teeth) in either arch\n* Orthodontic treatment plans involving tooth extractions in either arch\n* Nickel allergy\n* History of cleft lip and\u002For palate\n* Craniofacial syndromes","ALL","12 Years","18 Years",{"count":65,"type":66},20,"ESTIMATED","INTERVENTIONAL",[69],"NA","This randomized split-mouth clinical trial will compare digital and conventional indirect bonding techniques for fixed orthodontic bracket placement in adolescent patients requiring treatment in both dental arches.\n\nEach participant will receive both bonding techniques, with allocation of the digital and conventional indirect bonding procedures to the upper or lower arch determined by randomization. The study will evaluate the time required to complete bracket bonding procedures and the early clinical performance of the two techniques, assessed by bracket failure within the first month after appliance placement.",[72],"Malocclusion","2026-07-08",{"date":75,"type":76},"2026-07-09","ACTUAL",{"date":78,"type":76},"2025-09-03",{"date":80,"type":66},"2026-08-24",{"name":5,"class":6},1]