[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100602072":3},{"organization":4,"outcomesModule":7,"designInfo":27,"detailedDescription":34,"studyPopulation":26,"armGroups":35,"interventions":48,"overallOfficials":26,"centralContacts":57,"locations":67,"responsibleParty":424,"collaborators":26,"id":426,"slug":427,"hasResults":428,"nctId":429,"briefTitle":430,"officialTitle":431,"acronym":432,"eligibilityCriteria":433,"healthyVolunteers":428,"sex":434,"minAge":435,"maxAge":436,"enrollmentInfo":437,"targetDuration":26,"studyType":440,"phases":441,"briefSummary":443,"conditions":444,"keywords":446,"overallStatus":70,"whyStopped":26,"lastUpdateSubmitDate":451,"lastUpdatePostDateStruct":452,"startDateStruct":455,"completionDateStruct":457,"leadSponsor":459,"locationsCount":460},{"fullName":5,"class":6},"University Hospital, Bordeaux","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":26},[9],{"measure":10,"description":11,"timeFrame":12},"Dispensing of antibiotic","Dispensing of antibiotic for acute cystitis without risk of complication on the 14 days following the first visit to the pharmacy.","day 14 after inclusion",[14,17,20,23],{"measure":15,"description":16,"timeFrame":12},"Activity Impairment Assessment(AIA) scale","5-item ranging from 0 (no impact) to 4 (constant impact). It has no sub-dimensions and allows for an overall assessment (sum of the scores for each item) ranging from 0 (no discomfort\u002Fno incapacity) to 20 (total discomfort\u002F total incapacity).",{"measure":18,"description":19,"timeFrame":12},"Satisfaction scale","Satisfaction score on a scale from 0 (dissatisfaction) to 10 (total satisfaction)",{"measure":21,"description":22,"timeFrame":12},"O'Connor scale","16-item scale rated from 1 to 5. Each score is converted to a base of 100 (1=0, 5=100).\n\nThe total average of the items out of 100 determines:\n\n\\\u003C 25: Low conflict - the person is probably ready to make a decision. 25-37.5: Moderate conflict - some discomfort may still exist.\n\n≥ 37.5: High conflict - the person probably needs help deciding.",{"measure":24,"description":25,"timeFrame":12},"Medical consultation","Consultations with a doctor or at the emergency room for urinary tract infection and\u002For possible complications among patients diagnosed with uncomplicated cystitis within two weeks of visiting the pharmacy (telephone survey at two weeks).",null,{"allocation":28,"interventionModel":29,"interventionModelDescription":30,"primaryPurpose":31,"observationalModel":26,"timePerspective":26,"maskingInfo":32},"RANDOMIZED","PARALLEL","open-label, two-arms cluster randomized clinical trial","TREATMENT",{"masking":33,"maskingDescription":26,"whoMasked":26},"NONE","Each year, in France, more than 2.000.000 patients visit for a acute cystitis. The literature shows that acute cystitis without risk of complication cause pyelonephritis only on really rare situation, but french delegation protocols to pharmacist ask for systematic antibiotic therapy as soon as the diagnostic is made with the only goal to lowering symptomatology. Studies shows that some informed women would like not to take antibiotics while others studies show us that pain-killers could be as effective as antibiotics on case of low symptomatology.\n\nThis study will compare a group following only the French protocols for delegating acute cystitis to the pharmacist with a group using the same protocol, but supplementing it with a shared decision-making tool to determine whether, after being informed of the benefits and risks of this treatment, patients still wish to receive an antibiotic. Targeting instead of systematic prescription will reduce antibiotic consumption.\n\nAfter diagnostic of acute cystitis to a woman between 18 and 65 years, investigators check if they filing all study criteria and ask for authorization to add them to the study. Then they'll act following their group instruction, and get informations (antibiotic prescription or not, patient socio-demographic criteria). Then patients will be followed by telephone on D14 to know if they've take antibiotics and to obtain the following information: AIA scale, O'Connor Scale, Satisfaction scale, if there has been visit to the emergency room or doctor. Antibiotics delivery on pharmacy will be watch by National assurance number of the included patients",[36,42],{"label":37,"type":38,"description":39,"interventionNames":40},"Share making tool decision group","EXPERIMENTAL","woman, between 18 and 65 years, coming to a pharmacy randomized in the experimental group for symptom of acute cystitis without risk of complication",[41],"Other: Share making decision tool",{"label":43,"type":44,"description":45,"interventionNames":46},"Delegation protocol alone group","ACTIVE_COMPARATOR","woman, between 18 and 65 years, coming to a pharmacy randomized in the control group for symptom of acute cystitis without risk of complication",[47],"Other: Delegation protocol",[49,53],{"type":6,"name":50,"description":51,"armGroupLabels":52,"otherNames":26},"Share making decision tool","the experimental group will apply the delegation protocol, but if the protocol recommends antibiotic therapy, the researchers will propose a shared decision using a specific tool to determine with the patient whether to deliver the antibiotic",[37],{"type":6,"name":54,"description":55,"armGroupLabels":56,"otherNames":26},"Delegation protocol","the control group will apply the delegation protocol alone",[43],[58,63],{"name":59,"role":60,"phone":61,"phoneExt":26,"email":62},"Yves-Marie VINCENT, MD","CONTACT","05 57 57 13 11","yves-marie.vincent@u-bordeaux.fr",{"name":64,"role":60,"phone":65,"phoneExt":26,"email":66},"Pierre POULIZAC","05.57.82.08.49","pierre.poulizac@chu-bordeaux.fr",[68,89,104,118,131,140,155,166,180,195,206,221,235,251,266,275,290,305,320,335,344,358,373,384,399,410],{"facility":69,"status":70,"city":71,"state":26,"zip":72,"country":73,"countryCode":74,"cosmosGeoPoint":75,"geoPoint":80,"contacts":81},"Pharmacie Lemarquis","RECRUITING","Aire-sur-l'Adour","40800","France","FR",{"type":76,"coordinates":77},"Point",[78,79],-0.26276,43.70251,{"lat":79,"lon":78},[82,87],{"name":83,"role":60,"phone":84,"phoneExt":85,"email":86},"Paul LEMARQUIS","05.58.71.60.59","+33","pharmacie.lemarquis@gmail.com",{"name":83,"role":88,"phone":26,"phoneExt":26,"email":26},"PRINCIPAL_INVESTIGATOR",{"facility":90,"status":70,"city":91,"state":26,"zip":92,"country":73,"countryCode":74,"cosmosGeoPoint":93,"geoPoint":97,"contacts":98},"Pharmacie Lafitte","Arès","33740",{"type":76,"coordinates":94},[95,96],-1.13421,44.76576,{"lat":96,"lon":95},[99,103],{"name":100,"role":60,"phone":101,"phoneExt":85,"email":102},"Mathilde QUERAUX","05.56.60.24.39","phie.laffitte@orange.fr",{"name":100,"role":88,"phone":26,"phoneExt":26,"email":26},{"facility":105,"status":70,"city":106,"state":26,"zip":26,"country":73,"countryCode":74,"cosmosGeoPoint":107,"geoPoint":111,"contacts":112},"Pharmacie de Bon Encontre","Bon-Encontre",{"type":76,"coordinates":108},[109,110],0.67134,44.186,{"lat":110,"lon":109},[113,117],{"name":114,"role":60,"phone":115,"phoneExt":85,"email":116},"Nicolas De BOURY","05 53 96 07 12","pharmaciedebonencontre@outlook.fr",{"name":114,"role":88,"phone":26,"phoneExt":26,"email":26},{"facility":119,"status":70,"city":120,"state":26,"zip":26,"country":73,"countryCode":74,"cosmosGeoPoint":121,"geoPoint":125,"contacts":126},"CHU de Bordeaux","Bordeaux",{"type":76,"coordinates":122},[123,124],-0.58046,44.84124,{"lat":124,"lon":123},[127,128,129],{"name":59,"role":60,"phone":61,"phoneExt":26,"email":62},{"name":64,"role":60,"phone":65,"phoneExt":26,"email":66},{"name":130,"role":88,"phone":26,"phoneExt":26,"email":26},"Yves-Marie VINCENT, Dr",{"facility":132,"status":70,"city":133,"state":26,"zip":26,"country":73,"countryCode":74,"cosmosGeoPoint":26,"geoPoint":26,"contacts":134},"Pharmacie de Castets et Castillon","Castets Et Castillon",[135,139],{"name":136,"role":60,"phone":137,"phoneExt":85,"email":138},"Lisa SEBAIHI","5 56 62 83 21","pharmacie.decastets@gmail.com",{"name":136,"role":88,"phone":26,"phoneExt":26,"email":26},{"facility":141,"status":70,"city":142,"state":26,"zip":143,"country":73,"countryCode":74,"cosmosGeoPoint":144,"geoPoint":148,"contacts":149},"Pharmacie Pattyn Nizard","Caudebec-lès-Elbeuf","76320",{"type":76,"coordinates":145},[146,147],1.02195,49.28082,{"lat":147,"lon":146},[150,154],{"name":151,"role":60,"phone":152,"phoneExt":85,"email":153},"Laurence PATTYN-NIZARD","02.35.77.06.79","ordonnances@pharmapattyn.fr",{"name":151,"role":60,"phone":26,"phoneExt":26,"email":26},{"facility":156,"status":70,"city":142,"state":26,"zip":26,"country":73,"countryCode":74,"cosmosGeoPoint":157,"geoPoint":159,"contacts":160},"Pharmacie du mortier d'Or",{"type":76,"coordinates":158},[146,147],{"lat":147,"lon":146},[161,165],{"name":162,"role":60,"phone":163,"phoneExt":85,"email":164},"Romain THIEUBAUT","02 35 77 03 57","pro.pharmaciedumortierdor@gmail.com",{"name":162,"role":88,"phone":26,"phoneExt":26,"email":26},{"facility":167,"status":70,"city":168,"state":26,"zip":26,"country":73,"countryCode":74,"cosmosGeoPoint":169,"geoPoint":173,"contacts":174},"Pharmacie des 3 vallées","Creysse",{"type":76,"coordinates":170},[171,172],0.56551,44.85514,{"lat":172,"lon":171},[175,179],{"name":176,"role":60,"phone":177,"phoneExt":85,"email":178},"Boris BROUILLET","05 53 23 21 11","pharmaciedes3vallees@yahoo.com",{"name":176,"role":88,"phone":26,"phoneExt":26,"email":26},{"facility":181,"status":70,"city":182,"state":26,"zip":183,"country":73,"countryCode":74,"cosmosGeoPoint":184,"geoPoint":188,"contacts":189},"Pharmacie Saint-Jean d'Elbeuf","Elbeuf","76500",{"type":76,"coordinates":185},[186,187],1.00288,49.28669,{"lat":187,"lon":186},[190,194],{"name":191,"role":60,"phone":192,"phoneExt":85,"email":193},"Valérie QUICHON","02.35.77.09.97","pharmacie.saintjean-elbeuf@orange.fr",{"name":191,"role":88,"phone":26,"phoneExt":26,"email":26},{"facility":196,"status":70,"city":182,"state":26,"zip":183,"country":73,"countryCode":74,"cosmosGeoPoint":197,"geoPoint":199,"contacts":200},"Pharmacie Tranchant",{"type":76,"coordinates":198},[186,187],{"lat":187,"lon":186},[201,205],{"name":202,"role":60,"phone":203,"phoneExt":85,"email":204},"Angélique TRANCHANT","02.35.77.01.26","pharmacie.tranchant@gmail.com",{"name":202,"role":60,"phone":26,"phoneExt":26,"email":26},{"facility":207,"status":70,"city":208,"state":26,"zip":209,"country":73,"countryCode":74,"cosmosGeoPoint":210,"geoPoint":214,"contacts":215},"Pharmacie du Réolais","La Réole","33190",{"type":76,"coordinates":211},[212,213],-0.03857,44.58239,{"lat":213,"lon":212},[216,220],{"name":217,"role":60,"phone":218,"phoneExt":85,"email":219},"Vincent VAZQUEZ","05.56.61.01.60","vincent.vazquez@gmail.com",{"name":217,"role":88,"phone":26,"phoneExt":26,"email":26},{"facility":222,"status":70,"city":223,"state":26,"zip":26,"country":73,"countryCode":74,"cosmosGeoPoint":224,"geoPoint":228,"contacts":229},"Pharmacie Bougniot","Labouheyre",{"type":76,"coordinates":225},[226,227],-0.92062,44.21297,{"lat":227,"lon":226},[230,234],{"name":231,"role":60,"phone":232,"phoneExt":85,"email":233},"Marc DEVARIEUX","5 58 07 00 13","ph.marcdevarieux@gmail.com",{"name":231,"role":88,"phone":26,"phoneExt":26,"email":26},{"facility":236,"status":70,"city":237,"state":26,"zip":238,"country":73,"countryCode":74,"cosmosGeoPoint":239,"geoPoint":243,"contacts":244},"Pharmacie de Gascogne","Léguevin","31490",{"type":76,"coordinates":240},[241,242],1.23236,43.60028,{"lat":242,"lon":241},[245,249,250],{"name":246,"role":60,"phone":247,"phoneExt":85,"email":248},"Christine GESTAS","05.61.86.60.47","pharmaciedegascogne@wanadoo.fr",{"name":246,"role":60,"phone":26,"phoneExt":26,"email":26},{"name":246,"role":88,"phone":26,"phoneExt":26,"email":26},{"facility":252,"status":70,"city":253,"state":26,"zip":254,"country":73,"countryCode":74,"cosmosGeoPoint":255,"geoPoint":259,"contacts":260},"Pharmacie de l'Hotel de Ville","Malaunay","76770",{"type":76,"coordinates":256},[257,258],1.04292,49.5271,{"lat":258,"lon":257},[261,265],{"name":262,"role":60,"phone":263,"phoneExt":26,"email":264},"Etienne PELEGRIN","02.35.74.10.55","Pharmacie.malaunay@orange.fr",{"name":262,"role":60,"phone":26,"phoneExt":26,"email":26},{"facility":267,"status":70,"city":268,"state":26,"zip":26,"country":73,"countryCode":74,"cosmosGeoPoint":26,"geoPoint":26,"contacts":269},"Pharmacie de la Sèvre","Moncoutant Sur Sèvre",[270,274],{"name":271,"role":60,"phone":272,"phoneExt":85,"email":273},"Estelle DELABROYE","5 49 72 60 24","edelabroye@totum.fr",{"name":271,"role":88,"phone":26,"phoneExt":26,"email":26},{"facility":276,"status":70,"city":277,"state":26,"zip":278,"country":73,"countryCode":74,"cosmosGeoPoint":279,"geoPoint":283,"contacts":284},"Pharmacie du Pontreau","Niort","79000",{"type":76,"coordinates":280},[281,282],-0.45877,46.32313,{"lat":282,"lon":281},[285,289],{"name":286,"role":60,"phone":287,"phoneExt":85,"email":288},"Patrick LE PADELLEC","05.49.24.04.08","contact@pharmaciedupontreau.com",{"name":286,"role":60,"phone":26,"phoneExt":26,"email":26},{"facility":291,"status":70,"city":292,"state":26,"zip":293,"country":73,"countryCode":74,"cosmosGeoPoint":294,"geoPoint":298,"contacts":299},"Pharmacie Centrale","Plouha","22580",{"type":76,"coordinates":295},[296,297],-2.92795,48.6761,{"lat":297,"lon":296},[300,304],{"name":301,"role":60,"phone":302,"phoneExt":85,"email":303},"Angélique CHAPELAIN-FILLATRE","02.96.22.41.77","chapelainroche@gmail.com",{"name":301,"role":88,"phone":26,"phoneExt":26,"email":26},{"facility":306,"status":70,"city":307,"state":26,"zip":308,"country":73,"countryCode":74,"cosmosGeoPoint":309,"geoPoint":313,"contacts":314},"Pharmacie des Grandes Vignes","Preignac","33210",{"type":76,"coordinates":310},[311,312],-0.29522,44.58489,{"lat":312,"lon":311},[315,319],{"name":316,"role":60,"phone":317,"phoneExt":85,"email":318},"Marlène GERARD","05.56.63.27.42","pharmaciedepreignac@gmail.com",{"name":316,"role":88,"phone":26,"phoneExt":26,"email":26},{"facility":321,"status":70,"city":322,"state":26,"zip":26,"country":73,"countryCode":74,"cosmosGeoPoint":323,"geoPoint":327,"contacts":328},"Pharmacie Puymirol","Puymirol",{"type":76,"coordinates":324},[325,326],0.79615,44.18674,{"lat":326,"lon":325},[329,333],{"name":330,"role":60,"phone":331,"phoneExt":85,"email":332},"Mary-Luz RENAUD, Dr","9 66 11 14 27","pharmaciepuymirol@gmail.com",{"name":334,"role":88,"phone":26,"phoneExt":26,"email":26},"Mary-Luz RENAUD",{"facility":336,"status":70,"city":337,"state":26,"zip":26,"country":73,"countryCode":74,"cosmosGeoPoint":26,"geoPoint":26,"contacts":338},"Pharmacie de Saint-Ouen","SAINT-OUEN-de-thouverville",[339,343],{"name":340,"role":60,"phone":341,"phoneExt":85,"email":342},"Morgane LEFEBVRE","02 32 56 26 48","pharmaciedesaintouen@orange.fr",{"name":340,"role":88,"phone":26,"phoneExt":26,"email":26},{"facility":345,"status":70,"city":346,"state":26,"zip":26,"country":73,"countryCode":74,"cosmosGeoPoint":347,"geoPoint":351,"contacts":352},"Pharmacie du Château","Saint-Porchaire",{"type":76,"coordinates":348},[349,350],-0.78414,45.82101,{"lat":350,"lon":349},[353,357],{"name":354,"role":60,"phone":355,"phoneExt":85,"email":356},"Alexandre PEYRIDIEUX","5 46 95 60 25","alexandre@peyridieux.com",{"name":354,"role":88,"phone":26,"phoneExt":26,"email":26},{"facility":359,"status":70,"city":360,"state":26,"zip":361,"country":73,"countryCode":74,"cosmosGeoPoint":362,"geoPoint":366,"contacts":367},"Pharmacie des Jacobins","Saint-Sever","40500",{"type":76,"coordinates":363},[364,365],-0.57181,43.75726,{"lat":365,"lon":364},[368,372],{"name":369,"role":60,"phone":370,"phoneExt":85,"email":371},"Prunelle TAIEB","05.58.76.00.39","pharmadesjacobins@gmail.com",{"name":369,"role":88,"phone":26,"phoneExt":26,"email":26},{"facility":374,"status":70,"city":360,"state":26,"zip":26,"country":73,"countryCode":74,"cosmosGeoPoint":375,"geoPoint":377,"contacts":378},"Pharmacie du Cap de Gascogne",{"type":76,"coordinates":376},[364,365],{"lat":365,"lon":364},[379,383],{"name":380,"role":60,"phone":381,"phoneExt":85,"email":382},"Lisa FALLET","5 58 76 01 29","pharmacieducap@gmail.com",{"name":380,"role":88,"phone":26,"phoneExt":26,"email":26},{"facility":385,"status":70,"city":386,"state":26,"zip":387,"country":73,"countryCode":74,"cosmosGeoPoint":388,"geoPoint":392,"contacts":393},"Pharmacie de Bellevue","Saintes","17100",{"type":76,"coordinates":389},[390,391],-0.63489,45.74742,{"lat":391,"lon":390},[394,398],{"name":395,"role":60,"phone":396,"phoneExt":85,"email":397},"Cyrille PRINCE","05.46.93.15.88","pharmaciebellevue01@gmail.com",{"name":395,"role":88,"phone":26,"phoneExt":26,"email":26},{"facility":400,"status":70,"city":386,"state":26,"zip":26,"country":73,"countryCode":74,"cosmosGeoPoint":401,"geoPoint":403,"contacts":404},"Pharmacie de l'Olympia",{"type":76,"coordinates":402},[390,391],{"lat":391,"lon":390},[405,409],{"name":406,"role":60,"phone":407,"phoneExt":85,"email":408},"Charlotte CERTIN","5 46 74 37 51","chacertin@msn.com",{"name":406,"role":88,"phone":26,"phoneExt":26,"email":26},{"facility":411,"status":70,"city":412,"state":26,"zip":26,"country":73,"countryCode":74,"cosmosGeoPoint":413,"geoPoint":417,"contacts":418},"Pharmacie Lagoueyte","Soustons",{"type":76,"coordinates":414},[415,416],-1.32977,43.75165,{"lat":416,"lon":415},[419,423],{"name":420,"role":60,"phone":421,"phoneExt":85,"email":422},"Marc PRUJA","5 58 41 51 69","marco4064@yahoo.fr",{"name":420,"role":88,"phone":26,"phoneExt":26,"email":26},{"type":425,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100602072","dispensing-of-antibiotics-in-pharmacies-for-cystitis-according-to-a-delegation-protocol-impact-of-a-decision-support-tool-pharibo-pharmacy-and-resolved-antibiotherapy-for-urinary-tract-infections-100602072",false,"NCT07118748","Dispensing of Antibiotics in Pharmacies for Cystitis According to a Delegation Protocol, Impact of a Decision Support Tool. PHARIBO: PHarmacy and Resolved Antibiotherapy for Urinary Tract Infections","Dispensing of Antibiotics in Pharmacies for Cystitis According to a Delegation Protocol, Impact of a Decision Support Tool : a Randomised Cluster Trial. PHARIBO: PHarmacy and Resolved Antibiotherapy for Urinary Tract Infections","PHARIBO","Inclusion Criteria:\n\n* woman,\n* symptom of acute cystitis without risk of complication,\n* affiliated to the french public welfare system,\n* signed consent.\n\nExclusion Criteria:\n\n* anomaly of the urinary canal,\n* pregnancy, more than 3 cystitis during the last year,\n* cancer,\n* immunosuppression,\n* hemopathy,\n* fever,\n* back-pain,\n* severe renal failure,\n* refuse to give consent and previously participate to the study,\n* under guardianship.","FEMALE","18 Years","65 Years",{"count":438,"type":439},506,"ESTIMATED","INTERVENTIONAL",[442],"NA","The purpose of this trial is to demonstrate that when treating acute cystitis without risk of complication, pharmacists may use share Decision Making tool to help patients to better understand the stakes of taking antibiotics and adapt the management of the delegation protocol.\n\nThis will select patients in need of antibiotics and preserve the full-capacities of non-treated one.",[445],"Acute Cystitis",[447,448,449,450],"cystitis","professional delegation","share decision making","antibiotics","2026-08-27",{"date":453,"type":454},"2026-09-01","ACTUAL",{"date":456,"type":454},"2026-05-19",{"date":458,"type":439},"2026-11",{"name":5,"class":6},26]