[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646303":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":24,"locations":34,"responsibleParty":52,"collaborators":10,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":10,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":10,"studyType":68,"phases":10,"briefSummary":69,"conditions":70,"keywords":74,"overallStatus":37,"whyStopped":10,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Second Affiliated Hospital of Nanchang University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group with spherical equivalent change ≥0.50 diopters after cycloplegic refraction",null,"Adult myopes with a non-cycloplegic versus cycloplegic spherical equivalent difference of ≥0.50 diopters, for whom cycloplegic refraction is clinically warranted, received routine cycloplegic refraction with tropicamide; no other intervention was given.",[13],"Diagnostic Test: Machine learning model for predicting cycloplegic refraction",{"label":15,"type":10,"description":16,"interventionNames":17},"Group with spherical equivalent change \u003C0.50 diopters after cycloplegic refraction","Adult myopes with an absolute difference of less than 0.50 diopters between non-cycloplegic and cycloplegic spherical equivalent, for whom non-cycloplegic refraction is considered sufficient, received routine cycloplegic refraction with tropicamide; no additional intervention was applied.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"DIAGNOSTIC_TEST","Machine learning model for predicting cycloplegic refraction","The machine learning model was applied to each participant's non-cycloplegic parameters to predict cycloplegic spherical equivalent.",[15,9],[25,30],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"jian xiong","CONTACT","18170906556","894040417@qq.com",{"name":31,"role":27,"phone":32,"phoneExt":10,"email":33},"Fu Gui","1387910191","564436578@qq.com",[35],{"facility":36,"status":37,"city":38,"state":10,"zip":10,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"The Second Affiliated Hospital of Nanchang University, Nanchang, JiangXi 330000","RECRUITING","Jiangxi","China","CN",{"type":42,"coordinates":43},"Point",[44,45],105.19994,33.99934,{"lat":45,"lon":44},[48,50],{"name":49,"role":27,"phone":28,"phoneExt":10,"email":29},"Jian Xiong",{"name":31,"role":27,"phone":51,"phoneExt":10,"email":33},"13879101919",{"type":53,"investigatorFullName":49,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Associate research fellow; Attending physician","100646303","dl-models-predicting-cycloplegic-refractive-error-based-on-non-cycloplegic-parameters-in-myopic-adults-100646303",false,"NCT07690813","DL Models Predicting Cycloplegic Refractive Error Based on Non-Cycloplegic Parameters in Myopic Adults","Efficacy of Deep Learning Models for Predicting Cycloplegic Refractive Error Based on Non-Cycloplegic Parameters in Adults With Myopia","Inclusion Criteria:\n\n1. Age 18 to 60 years, of either sex;\n2. Spherical equivalent between -0.50 diopters and -10.00 diopters, with myopia in one or both eyes, and with cylinder of 4.00 diopters or less;\n3. Best-corrected visual acuity of 20\u002F25 or better in each eye;\n4. Clear cornea, no keratoconus, corneal scarring, or other pathologies; clear lens;\n5. Intraocular pressure of 21 mmHg or less, with no history of glaucoma;\n6. No history of ocular surgery, especially corneal refractive surgery or cataract surgery;\n7. Time interval between non-cycloplegic refraction and cycloplegic refraction of 7 days or less, with complete data.\n\nExclusion Criteria:\n\n1. Incomplete clinical data to support the diagnosis;\n2. Ocular conditions such as subclinical keratoconus, keratoconus, or moderate-to-severe corneal haze or leukoma;\n3. Allergy or contraindication to cycloplegic agents;\n4. Refusal to participate in the study.","ALL","18 Years","47 Years",{"count":66,"type":67},2500,"ESTIMATED","OBSERVATIONAL","This study presents a machine learning model that predicts cycloplegic refraction in adults with myopia using standard non-cycloplegic eye measurements, aiming to reduce the need for cycloplegic drops while still identifying patients who require them.",[71,72,73],"Refractive Errors","Cycloplegic Refraction","Accommodation",[73,75,76],"Cycloplegic refraction","Refractive errors","2026-07-07",{"date":79,"type":80},"2026-07-09","ACTUAL",{"date":82,"type":80},"2023-10-03",{"date":84,"type":67},"2026-11-25",{"name":5,"class":6},1]