[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650562":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":34,"locations":10,"responsibleParty":40,"collaborators":10,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":52,"sex":53,"minAge":54,"maxAge":10,"enrollmentInfo":55,"targetDuration":10,"studyType":58,"phases":10,"briefSummary":59,"conditions":60,"keywords":10,"overallStatus":62,"whyStopped":10,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":10},{"fullName":5,"class":6},"Assiut University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Healthy controls",null,"Twenty-eight healthy volunteers without a history of optic neuritis or other optic nerve disorders. Participants will undergo MRI examination for comparison with the optic neuritis group.",[13],"Device: MRI",{"label":15,"type":10,"description":16,"interventionNames":17},"Optic Neuritis Patients","Twenty-eight patients diagnosed with optic neuritis who will undergo MRI examination for evaluation of imaging findings.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"DEVICE","MRI","DTI and DIR",[9,15],[25,28,30,32],{"name":26,"affiliation":5,"role":27},"Prof.dr afaf Abdkader Hassan, Professor","STUDY_CHAIR",{"name":29,"affiliation":5,"role":27},"Dr omran Khodary Qenway, Assistant professor",{"name":31,"affiliation":5,"role":27},"Dr Samaa Mustafa El kossi, Lecturer",{"name":33,"affiliation":5,"role":27},"Dr.asmaa Mohamed Mohamed, Lecturer",[35],{"name":36,"role":37,"phone":38,"phoneExt":10,"email":39},"Merna Nemr, Assistant lecturer","CONTACT","01020731292","monna.merna13@gmail.com",{"type":41,"investigatorFullName":42,"investigatorTitle":43,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Merna youssef nemr","Assistant lecturer","100650562","dti--dir-in-optic-neuritis-100650562",false,"NCT07748819","DTI & DIR in Optic Neuritis","MRI Evaluation of Optic Neuritis : Integrating Double Inversion Recovery and Diffusion Tensor Imaging .","DTI & DIR","Inclusion Criteria:\n\n* Age above 18 years.\n* Clinically suspected optic neuritis.\n* Evidence of multiple sclerosis or other demyelinating diseases.\n\nExclusion Criteria:\n\n* Traumatic optic neuritis.\n* Systemic diseases affecting the optic nerve.\n* Contraindications to MRI.",true,"ALL","18 Years",{"count":56,"type":57},56,"ESTIMATED","OBSERVATIONAL","To evaluate the role of Double Inversion Recovery (DIR) and Diffusion Tensor Imaging (DTI) in the assessment of optic neuritis and to correlate imaging findings with clinical and visual outcomes.",[61],"Optic Nerve Disease","NOT_YET_RECRUITING","2026-07-31",{"date":65,"type":66},"2026-08-06","ACTUAL",{"date":68,"type":57},"2026-08-01",{"date":70,"type":57},"2028-06-30",{"name":5,"class":6}]