[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100576429":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":23,"locations":32,"responsibleParty":50,"collaborators":22,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":62,"sex":63,"minAge":64,"maxAge":22,"enrollmentInfo":65,"targetDuration":22,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":22,"overallStatus":35,"whyStopped":22,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"IRCCS Policlinico S. Donato","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"HEALTHY SUBJECTS","EXPERIMENTAL","An experimental setup will be devised for the simultaneous monitoring and recording of EEG, ECG, AP, and R together with CBF in healthy volunteers. The experimental protocol including physiological data recordings includes three sessions lasting 10 minutes each: a session at resting state in supine position, a session during autonomic challenge obtained via active standing evoking reflex sympathetic activation, and a session of emotional elicitation via the administration of videos. The overall duration of the experiment is therefore 30 minutes. A total of 40 short video clips of the duration of 15 seconds each will be presented to a total of 50 voluteers will be recruited for the IDEALE study.",[13],"Diagnostic Test: Active standing",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DIAGNOSTIC_TEST","Active standing","a session at resting state in supine position, a session during autonomic challenge obtained via active standing evoking reflex sympathetic activation, and a session of emotional elicitation via the administration of videos",[9],[21],"Emotional tests",null,[24,29],{"name":25,"role":26,"phone":27,"phoneExt":22,"email":28},"Vlasta Bari, PhD","CONTACT","+390252774381","vlasta.bari@grupposandonato.it",{"name":30,"role":26,"phone":27,"phoneExt":22,"email":31},"Pavandeep Singh","pavandeep.singh@grupposandonato.it",[33],{"facility":34,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"IRCCS Policlinico San Donato","RECRUITING","San Donato Milanese","Milano","20097","Italy","IT",{"type":42,"coordinates":43},"Point",[44,45],9.26838,45.41047,{"lat":45,"lon":44},[48],{"name":25,"role":26,"phone":49,"phoneExt":22,"email":28},"39 02 5277 4381",{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":22,"oldOrganization":22},"PRINCIPAL_INVESTIGATOR","Vlasta Bari","Associate Professor in Bioengineeering","100576429","dynamic-cardio-vascular-cerebro-vascular-and-cortical-interaction-in-healthy-adult-subjects-100576429",false,"NCT06785181","Dynamic Cardio-vascular, Cerebro-vascular and Cortical Interaction in Healthy Adult Subjects","Dynamic Cardio-, Cerebro-vascular and Cortical Interaction in Healthy Adult Subjects","IDEALE","Inclusion Criteria:\n\n* age older than 18 years\n* spontaneous sinus rhythm\n* signed informed consent\n\nExclusion Criteria:\n\n* Definite diseases of the Autonomic Nervous System (SNA) or the cardiovascular system\n* Central nervous system disorders\n* subjects under drug therapy that may affect the cardiovascular system\n* pregnancy\n* previous diagnosis of depression",true,"ALL","18 Years",{"count":66,"type":67},50,"ESTIMATED","INTERVENTIONAL",[70],"NA","IDEALE aims to assess the status of autonomic function, cerebral autoregulation (CA) and cortical activity in healthy subjects and correlate these functions with the psychological dimension of the subjects.\n\nTo this end, parameters of cardiac, cortical, vascular and cerebrovascular variability derived from electrocardiographic, electroencephalographic, respiratory movement, blood pressure, transcranial Doppler signals will be acquired and analysed for each healthy volunteer (TCD) and Laser-Doppler transcutaneous, during a phase of clinostatism (REST) and one of active orthostatism (STAND). In addition, volunteers will be submitted to psychometric tests (Chieti Affective Action Videos, CAAV) to assess the presence of depressive symptoms.",[73],"Cardiac Disease","2026-07-02",{"date":76,"type":77},"2026-07-06","ACTUAL",{"date":79,"type":77},"2024-10-03",{"date":81,"type":67},"2027-10-03",{"name":5,"class":6},1]