[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100651102":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":33,"locations":39,"responsibleParty":75,"collaborators":78,"id":83,"slug":84,"hasResults":85,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":89,"eligibilityCriteria":90,"healthyVolunteers":85,"sex":91,"minAge":92,"maxAge":93,"enrollmentInfo":94,"targetDuration":97,"studyType":98,"phases":10,"briefSummary":99,"conditions":100,"keywords":104,"overallStatus":41,"whyStopped":10,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":124},{"fullName":5,"class":6},"Nanfang Hospital, Southern Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Flow Diverter Group",null,"Patients with unruptured wide-neck intracranial bifurcation aneurysms who receive flow diverter treatment in routine clinical practice.",[13],"Device: Flow Diverter",{"label":15,"type":10,"description":16,"interventionNames":17},"Stent-Assisted Coiling Group","Patients with unruptured wide-neck intracranial bifurcation aneurysms who receive stent-assisted coiling in routine clinical practice.",[18],"Device: Stent-Assisted Coiling",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"DEVICE","Flow Diverter","Flow diverter treatment will be performed according to routine clinical practice and relevant guidelines. A flow-diverting stent will be deployed to cover the aneurysm neck after angiographic evaluation and device sizing. Perioperative management and antiplatelet therapy will be performed according to the study protocol and clinical practice.",[9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":10},"Stent-Assisted Coiling","Stent-assisted coiling will be performed according to routine clinical practice and relevant guidelines. A stent will be deployed across the aneurysm neck, followed by coil embolization of the aneurysm. Perioperative management and antiplatelet therapy will be performed according to the study protocol and clinical practice.",[15],[30],{"name":31,"affiliation":5,"role":32},"Wenfeng Feng, MD","PRINCIPAL_INVESTIGATOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":10,"email":38},"Huibin Kang Study Contact, MD","CONTACT","13520296286","kanghuibindoctor@163.com",[40,57,66],{"facility":5,"status":41,"city":42,"state":43,"zip":10,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"RECRUITING","Guangzhou","Guangdong","China","CN",{"type":47,"coordinates":48},"Point",[49,50],113.25,23.11667,{"lat":50,"lon":49},[53],{"name":54,"role":36,"phone":55,"phoneExt":10,"email":56},"Wenfeng Feng Feng, Principal Investigator, MD","13501509911","fengwf1967@163.com",{"facility":58,"status":41,"city":42,"state":10,"zip":10,"country":44,"countryCode":45,"cosmosGeoPoint":59,"geoPoint":61,"contacts":62},"Guangdong Province People's Hospital",{"type":47,"coordinates":60},[49,50],{"lat":50,"lon":49},[63],{"name":64,"role":36,"phone":10,"phoneExt":10,"email":65},"Shengpan Chen, MD","19801168712@163.com",{"facility":67,"status":41,"city":42,"state":10,"zip":10,"country":44,"countryCode":45,"cosmosGeoPoint":68,"geoPoint":70,"contacts":71},"Zhujiang Hospital, Southern Medical University",{"type":47,"coordinates":69},[49,50],{"lat":50,"lon":49},[72],{"name":73,"role":36,"phone":10,"phoneExt":10,"email":74},"Xin Feng, Principal Investigator","11111111@163.com",{"type":32,"investigatorFullName":76,"investigatorTitle":77,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Feng wen feng","Principal Investigator",[79,81],{"name":80,"class":6},"Zhujiang Hospital",{"name":58,"class":82},"UNKNOWN","100651102","early-complications-after-flow-diverter-versus-stent-assisted-coiling-for-unruptured-wide-neck-intracranial-bifurcation-aneurysms-100651102",false,"NCT07754188","Early Complications After Flow Diverter Versus Stent-Assisted Coiling for Unruptured Wide-Neck Intracranial Bifurcation Aneurysms","Early Complications After Flow Diverter Versus Stent-Assisted Coiling for Unruptured Wide-Neck Intracranial Bifurcation Aneurysms: A Prospective Real-World Cohort Study","FD-SAC BAS","Inclusion Criteria:\n\n* Voluntarily provides written informed consent.\n* Aged 18 to 75 years.\n* Diagnosed by CTA, MRA, or DSA as having an unruptured, bifurcation, saccular, wide-neck intracranial aneurysm.\n* Able to understand the purpose of the study.\n\nExclusion Criteria:\n\n* Patients with two or more multiple aneurysms, all of which require treatment within 1 year.\n* Patients with other cerebrovascular diseases such as arteriovenous malformation or moyamoya disease.\n* Patients with ruptured aneurysms or narrow-neck aneurysms.\n* Patients who experienced stroke, including cerebral hemorrhage or cerebral infarction, within the past 1 month.\n* Patients with poor clinical condition, defined as modified Rankin Scale score ≥3.\n* Patients who have already planned to undergo surgical or interventional treatment within 3 months.\n* Patients considered by the investigator to be unsuitable for endovascular treatment, such as those with no suitable vascular access, excessively tortuous vessels, or difficulty in stent delivery.\n* Patients unsuitable for anesthesia or endovascular treatment, including those with major heart, lung, liver, spleen, or kidney disease, brain tumor, severe active infection, disseminated intravascular coagulation, or a history of severe psychiatric disorder.\n* Patients unable to receive antiplatelet or anticoagulant therapy.\n* Patients with a previous or possible severe reaction to contrast agents that would prevent completion of pre-treatment medication or treatment.\n* Patients with a known history of allergy to cobalt-chromium or nickel-titanium alloy materials.\n* Patients who participated in another drug or medical device clinical trial before enrollment and have not reached the time point of the primary endpoint.\n* Pregnant or lactating women.\n* Patients with life expectancy less than 12 months.\n* Patients judged by the investigator to have poor compliance and inability to complete the study as required","ALL","18 Years","75 Years",{"count":95,"type":96},274,"ESTIMATED","30 Days","OBSERVATIONAL","This prospective real-world cohort study aims to compare early postoperative complications between flow diverter treatment and stent-assisted coiling in patients with unruptured wide-neck intracranial bifurcation aneurysms. A total of 274 patients from three centers in China will be enrolled and assigned to the flow diverter group or the stent-assisted coiling group according to the treatment received in routine clinical practice. The primary outcome is a composite of any stroke or all-cause death within 30 days after the procedure. The study will also collect demographic, clinical, laboratory, imaging, aneurysm morphological, procedural, and follow-up data to evaluate the safety of these two endovascular treatment strategies in a real-world setting.",[101,102,103],"Unruptured Intracranial Aneurysm","Intracranial Bifurcation Aneurysm","Wide-Neck Aneurysm",[105,106,107,108,109,110,111,112,113,114],"Intracranial bifurcation aneurysm","Wide-neck aneurysm","Flow diverter","Stent-assisted coiling","Endovascular treatment","Early complications","Stroke","All-cause mortality","Real-world study","Prospective cohort","2026-08-04",{"date":117,"type":118},"2026-08-10","ACTUAL",{"date":120,"type":118},"2026-03-19",{"date":122,"type":96},"2028-03-19",{"name":5,"class":6},3]