[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646973":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":26,"responsibleParty":42,"collaborators":10,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":48,"sex":54,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":10,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Ankara University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Acute Myocardial Infarction Patients",null,"Patients with acute myocardial infarction who underwent FAPI PET\u002FMR as part of the study protocol. Imaging findings will be analyzed in relation to infarct-related clinical, laboratory, and cardiac imaging parameters.",[13],"Diagnostic Test: 68Ga-FAPI-04 PET\u002FMR",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","68Ga-FAPI-04 PET\u002FMR","Hybrid 68Ga-FAPI PET\u002FMR performed to evaluate myocardial fibroblast activation following acute myocardial infarction. PET and MR imaging findings will be analyzed in relation to infarct characteristics, myocardial function, and clinical outcomes.",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Elgin Ozkan, Prof.Dr.","CONTACT","+90 312 595 6445","ozkanelgin@yahoo.com",[27],{"facility":28,"status":29,"city":30,"state":10,"zip":31,"country":32,"countryCode":10,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"Ankara University Faculty of Medicine, Department of Nuclear Medicine","RECRUITING","Ankara","06590","Turkey (Türkiye)",{"type":34,"coordinates":35},"Point",[36,37],32.85427,39.91987,{"lat":37,"lon":36},[40],{"name":41,"role":23,"phone":10,"phoneExt":10,"email":25},"Elgin Ozkan, Prof. Dr.",{"type":43,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Elgin Ozkan","Prof.Dr.","100646973","early-ga-68-fapi-petmr-after-acute-myocardial-infarction-100646973",false,"NCT07684924","Early Ga-68 FAPI PET\u002FMR After Acute Myocardial Infarction","Early Ga-68 FAPI PET\u002FMR for Assessment of Left Ventricular Remodeling After Acute Myocardial Infarction: A Prospective Single-Center Observational Study","REMODEL-FAPI","Inclusion Criteria:\n\n* Age ≥18 years.\n* Diagnosis of acute myocardial infarction according to current guideline criteria.\n* Successful coronary revascularization when clinically indicated.\n* Ability to undergo FAPI PET\u002FMR.\n* Written informed consent.\n\nExclusion Criteria:\n\n* Contraindications to MRI (e.g., non-MR-compatible implanted devices, severe claustrophobia).\n* Pregnancy or breastfeeding.\n* Severe renal impairment precluding gadolinium administration (if contrast-enhanced MR is performed).\n* Inability to provide informed consent.\n* Any condition considered by the investigator to interfere with study participation.","ALL","18 Years","90 Years",{"count":58,"type":59},25,"ESTIMATED","OBSERVATIONAL","Acute myocardial infarction (AMI) initiates a complex myocardial repair process involving inflammation, fibroblast activation, and extracellular matrix remodeling, which may ultimately lead to adverse left ventricular remodeling and impaired cardiac function. Fibroblast activation protein (FAP)-targeted positron emission tomography (PET) enables noninvasive visualization of activated fibroblasts and may provide an early imaging biomarker of myocardial remodeling. This prospective single-center observational study aims to evaluate myocardial fibroblast activation using Ga-68 FAPI PET\u002FMR performed approximately 10 ± 2 days after AMI and to investigate its association with subsequent left ventricular remodeling. Serial cardiac magnetic resonance (CMR) examinations will be performed at 3 and 6 months to assess changes in ventricular function and remodeling. The study will investigate whether early myocardial FAPI uptake is associated with subsequent structural and functional changes detected by CMR and evaluate the potential role of Ga-68 FAPI PET\u002FMR as an imaging biomarker for post-infarction remodeling.",[63],"Acute Myocardial Infarction (AMI)",[65,66,67,68,69,70],"Ga-68 FAPI","FAPI PET\u002FMR","Cardiac PET","Left Ventricular Remodeling","Cardiac Magnetic Resonance","Fibroblast Activation Protein","2026-07-24",{"date":73,"type":74},"2026-07-27","ACTUAL",{"date":76,"type":74},"2026-07-01",{"date":78,"type":59},"2028-06-29",{"name":5,"class":6},1]