[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100651328":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":11,"centralContacts":11,"locations":22,"responsibleParty":42,"collaborators":11,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":11,"eligibilityCriteria":50,"healthyVolunteers":46,"sex":51,"minAge":52,"maxAge":11,"enrollmentInfo":53,"targetDuration":11,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":11,"overallStatus":62,"whyStopped":11,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":72},{"fullName":5,"class":6},"Hospital Universitari Vall d'Hebron Research Institute","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Sacral neuromodulation","EXPERIMENTAL",null,[13],"Device: Sacral neuromodulation",{"label":15,"type":16,"description":11,"interventionNames":11},"Personalized conservative treatment","NO_INTERVENTION",[18],{"type":19,"name":9,"description":20,"armGroupLabels":21,"otherNames":11},"DEVICE","Sacral neuromodulation implantation within 120 days from discharge following rectal surgery or bowel reconstruction (ileostomy closure)",[9],[23],{"facility":24,"status":11,"city":25,"state":26,"zip":27,"country":28,"countryCode":29,"cosmosGeoPoint":30,"geoPoint":35,"contacts":36},"Vall d'Hebron Barcelona Hospital Campus","Barcelona","Catalonia","08035","Spain","ES",{"type":31,"coordinates":32},"Point",[33,34],2.15899,41.38879,{"lat":34,"lon":33},[37],{"name":38,"role":39,"phone":40,"phoneExt":11,"email":41},"Franco Marinello, Dr.","CONTACT","+34 934896587","franco.marinello@vallhebron.cat",{"type":43,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100651328","early-implementation-of-sacral-neuromodulation-in-patients-with-low-anterior-resection-syndrome-100651328",false,"NCT07761884","Early Implementation of Sacral Neuromodulation in Patients With Low Anterior Resection Syndrome.","Early Implementation of Sacral Neuromodulation in Patients With Low Anterior Resection Syndrome: a Randomized, Multicenter, Prospective, Open-label, Pragmatic Study.","Inclusion Criteria:\n\n* Adult patients (18 years of age or older) who are capable of signing the appropriate informed consent form.\n* Patients who have undergone an anterior rectal resection for rectal cancer, with an anastomosis, whether or not they have received neoadjuvant therapy, and who have bowel function, either via a direct anastomosis or following reconstruction of a lateral ileostomy.\n* Patients who experience more than 6 episodes of urgency and\u002For incontinence in the following two weeks after the screening visit, as recorded in a daily bowel diary.\n* Patients with a LARS score \\>21 points (major or minor LARS).\n* Patients who report at least one symptom and one consequence as defined by the international definition.\n\nExclusion Criteria:\n\n* Metastatic disease at the time of surgery.\n* Need for adjuvant chemotherapy at the time of assessment.\n* Active chemotherapy.\n* Patients with an ileostomy.\n* Intellectual or language-related difficulty in answering the questionnaires.\n* Refusal to participate in the study or failure to commit to follow-up visits.\n* Patients with contraindications for sacral neuromodulation implantation (those with pacemakers, active infections, or allergies to prosthetic materials).\n* Patients with active inflammatory bowel disease at the time of surgery.\n* Patients who have undergone other intestinal resections in addition to rectal resection.","ALL","18 Years",{"count":54,"type":55},40,"ESTIMATED","INTERVENTIONAL",[58],"NA","A randomized, prospective, multicenter, open-label, pragmatic pilot study of patients with Low Anterior Resection Syndrome treated early (\\\u003C120 days after discharge following intestinal bypass reconstruction) with sacral nerve root neuromodulation, compared with another group receiving personalized conservative treatment as performed in routine clinical practice.",[61],"Low Anterior Resection Syndrome (LARS)","NOT_YET_RECRUITING","2026-08-10",{"date":65,"type":66},"2026-08-12","ACTUAL",{"date":68,"type":55},"2026-08",{"date":70,"type":55},"2030-02",{"name":5,"class":6},1]