[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649218":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":34,"locations":39,"responsibleParty":56,"collaborators":60,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":64,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":25,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":84,"overallStatus":42,"whyStopped":25,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Alma Mater Europaea - Slovenia","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Early postoperative physiotherapy","EXPERIMENTAL","Participants receive a standardized early postoperative physiotherapy program initiated within the first postoperative hours according to the study protocol, in addition to standard perioperative management.",[13],"Procedure: Early postoperative physiotherapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard postoperative care","ACTIVE_COMPARATOR","Participants receive standard postoperative care, including routine postoperative physiotherapy according to institutional practice.",[19],"Procedure: Standard postoperative care",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Participants receive an early postoperative physiotherapy protocol initiated within the first 24 hours after elective cardiac surgery. The intervention includes breathing exercises, airway clearance techniques, early mobilization, progressive ambulation, and individualized therapeutic exercises according to a standardized protocol in addition to standard postoperative care.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Participants receive standard postoperative care, including routine postoperative physiotherapy according to institutional practice without the structured early physiotherapy protocol.",[15],[30],{"name":31,"affiliation":32,"role":33},"Dijana Filipović, MSc","Clinical Hospital Centre Zagreb","PRINCIPAL_INVESTIGATOR",[35],{"name":31,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","+385 99 4663124","dijana.filipovic@kbc-zagreb.hr",[40],{"facility":41,"status":42,"city":43,"state":25,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"University Hospital Centre Zagreb","RECRUITING","Zagreb","10000","Croatia","HR",{"type":48,"coordinates":49},"Point",[50,51],15.97798,45.81444,{"lat":51,"lon":50},[54],{"name":31,"role":36,"phone":55,"phoneExt":25,"email":38},"+385 99 4663 124",{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","Dijana Filipović","Principal Investigator",[61],{"name":32,"class":6},"100649218","early-postoperative-physiotherapy-to-prevent-respiratory-insufficiency-after-elective-heart-surgery-100649218",false,"NCT07730034","Early Postoperative Physiotherapy to Prevent Respiratory Insufficiency After Elective Heart Surgery","Early Postoperative Physiotherapy in the Prevention Respiratory Insufficiency After Elective Heart Surgery","EPP-CABG","Inclusion Criteria:\n\n* Adults aged 18-80 years\n* Male and female participants\n* Elective coronary artery bypass grafting (CABG)\n* Body mass index (BMI) \\\u003C 30 kg\u002Fm²\n* Left ventricular ejection fraction (EF) \\> 25%\n* Extubated on postoperative day 0 (POD 0)\n* Able and willing to provide written informed consent\n* Able to perform spirometry and follow study instructions\n\nExclusion Criteria:\n\n* Refusal or inability to provide informed consent\n* Emergency CABG surgery\n* Previous cardiac surgery\n* Severe cardiac arrhythmias (e.g., ventricular tachycardia\u002Ffibrillation, third-degree atrioventricular block)\n* Previous stroke\n* Motor impairment of upper or lower extremities due to neurological or musculoskeletal disease\n* Dyskinesia\n* Not extubated on POD 0\n* Significant postoperative neurological complications\n* Peripheral arterial disease of the lower extremities or previous lower-limb amputation\n* Acute or chronic pulmonary disease\n* Preoperative FEV1 \\\u003C30% of predicted (greater than 70% reduction)\n* Inability to perform spirometry correctly\n* Cancelled surgery after preoperative assessment\n* Extubation later than 24 hours after surgery\n* Requirement for continuous positive airway pressure (CPAP) after extubation SpO₂ \\\u003C90% one hour after extubation despite oxygen supplementation (4 L\u002Fmin by nasal cannula)\n* Return to the operating room after the initial CABG procedure\n* Requirement for dialysis (acute or chronic)","ALL","18 Years","80 Years",{"count":74,"type":75},40,"ESTIMATED","INTERVENTIONAL",[78],"NA","This study aims to determine whether starting respiratory physiotherapy one hour after removal of the breathing tube following elective coronary artery bypass graft (CABG) surgery leads to better recovery than the current standard approach, in which physiotherapy begins on the first postoperative day. The study will evaluate whether earlier physiotherapy improves lung function, reduces postoperative pulmonary complications, shortens intensive care unit and hospital stay, decreases pain and anxiety, and improves overall recovery after surgery. The main question is whether very early postoperative respiratory physiotherapy provides additional benefits for patients recovering from elective heart surgery compared with standard postoperative care.",[81,82,83],"CABG","Respiratory Insufficiency","Postoperative Pulmonary Complications (PPCs)",[85,9,86,87,88,89],"Coronary artery bypass grafting (CABG)","Respiratory physiotherapy","Cardiac surgery","Pulmonary rehabilitation","Respiratory insufficiency","2026-08-11",{"date":92,"type":93},"2026-08-12","ACTUAL",{"date":95,"type":93},"2026-08-04",{"date":97,"type":75},"2027-06",{"name":58,"class":6},1]