[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100645450":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":18,"locations":18,"responsibleParty":25,"collaborators":29,"id":32,"slug":33,"hasResults":34,"nctId":35,"briefTitle":36,"officialTitle":37,"acronym":18,"eligibilityCriteria":38,"healthyVolunteers":34,"sex":39,"minAge":40,"maxAge":41,"enrollmentInfo":42,"targetDuration":18,"studyType":45,"phases":46,"briefSummary":48,"conditions":49,"keywords":53,"overallStatus":59,"whyStopped":18,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":18},{"fullName":5,"class":6},"Izmir Kavram Vocational School","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental","EXPERIMENTAL","During AVF cannulation, immediately before needle insertion, the research nurse will instruct the patient to begin the breathing exercise. The patient will perform the following cycle while the cannulation procedure (skin preparation, needle insertion) is underway:\n\n* 4 seconds: Take a slow, deep breath through the nose.\n* 7 seconds: Hold your breath.\n* 8 seconds: Exhale slowly and completely through the mouth, pursing the lips slightly.\n\n  3\\. Number of Repetitions: This cycle will be repeated 5-6 times in succession, covering the duration of the cannulation procedure. The total duration of the exercise will be approximately 2-3 minutes.",[13],"Behavioral: Breathing technique",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","NO_INTERVENTION","Participants in the control group, on the other hand, will continue with their current routine hemodialysis care and standard cannulation procedures (without any structured breathing exercises).",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"BEHAVIORAL","Breathing technique","A non-pharmacological behavioral intervention utilizing the 4-7-8 breathing technique. Prior to the first session, a researcher nurse provides brief face-to-face training and an instructional video sent to participants' smartphones for home practice. During AVF cannulation in a comfortable position, the cycle begins just before and continues through needle insertion: inhale for 4 seconds, hold for 7, exhale for 8 through pursed lips. This 5-6-cycle sequence covers the entire \\~2-3 minute procedure. Applied three times weekly for four weeks, with pain assessed post-cannulation via VAS (0-10). The intervention reduces procedural pain by activating the parasympathetic system, promoting relaxation, decreasing anxiety, and modulating central pain processing.",[9],{"type":26,"investigatorFullName":27,"investigatorTitle":28,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Izmir Konak","Assistant Professor Dr",[30],{"name":31,"class":6},"Izmir Bakircay University","100645450","effect-of-4-7-8-breathing-on-av-fistula-needle-pain-in-dialysis-patients-100645450",false,"NCT07700680","Effect of 4-7-8 Breathing on AV Fistula Needle Pain in Dialysis Patients","The Effect of a 4-7-8 Breathing Exercise Program on the Management of Arteriovenous Fistula Intervention Pain in Hemodialysis Patients: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Being 18-85 years of age or older\n\n  * Receiving HD treatment 3 days a week\n  * Being able to read and write\n  * Having no hearing impairment\n  * Having Turkish as their native language\n  * Having received HD treatment for at least 6 months\n  * Having a VAS pain score \\>3\n  * Agreeing to listen to music\n\nExclusion Criteria:\n\n* Having a psychological disorder\n\n  * Having communication problems\n  * Having cancer\n  * Not wanting to participate in the study","ALL","18 Years","85 Years",{"count":43,"type":44},80,"ESTIMATED","INTERVENTIONAL",[47],"NA","For many hemodialysis patients, needle insertion into the vascular access site (fistula) is a significant source of pain and anxiety. In this study, patients will be guided to perform breathing exercises using the 4-7-8 breathing technique during needle insertion to reduce this pain. A total of 80 adult patients undergoing regular hemodialysis at Izmir Atatürk Training and Research Hospital will be randomly assigned to two groups: an intervention group and a control group. Participants in the intervention group will be taught a standardized intervention program consisting solely of the 4-7-8 breathing technique, to be applied before and during AVF cannulation. The program will be implemented during every hemodialysis session (three times a week) for one week. The technique will be explained in person by a research nurse before the first session, and patients will be provided with a short instructional video demonstrating the technique step by step. The video will be sent to patients' smartphones to encourage them to practice at home. Participants in the control group, however, will continue with their current routine hemodialysis care and standard cannulation procedures (without any structured breathing exercises). The results of this study may provide nurses and patients with easy-to-use, evidence-based options to make hemodialysis needle procedures less painful and stressful.",[50,51,52],"Chronic Kidney Diseases","Pain, Procedural","Arteriovenous Fistula",[54,55,56,57,58],"Non-pharmacological Pain Management","Hemodialysis","Vascular Access","Cannulation Pain","4-7-8 Breathing Technique","NOT_YET_RECRUITING","2026-07-14",{"date":62,"type":63},"2026-07-15","ACTUAL",{"date":65,"type":44},"2026-07-20",{"date":67,"type":44},"2027-01-30",{"name":5,"class":6}]