[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100654013":3},{"organization":4,"outcomesModule":7,"designInfo":17,"detailedDescription":25,"studyPopulation":16,"armGroups":26,"interventions":54,"overallOfficials":70,"centralContacts":75,"locations":81,"responsibleParty":97,"collaborators":16,"id":100,"slug":101,"hasResults":102,"nctId":103,"briefTitle":104,"officialTitle":104,"acronym":16,"eligibilityCriteria":105,"healthyVolunteers":106,"sex":107,"minAge":108,"maxAge":109,"enrollmentInfo":110,"targetDuration":16,"studyType":113,"phases":114,"briefSummary":116,"conditions":117,"keywords":119,"overallStatus":122,"whyStopped":16,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":132},{"fullName":5,"class":6},"National University of Singapore","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":16,"otherOutcomes":16},[9,13],{"measure":10,"description":11,"timeFrame":12},"Concentration of plasma carotenoids","Concentration of plasma carotenoids hourly","From start of salad consumption to the end of acute period (8 hours)",{"measure":14,"description":15,"timeFrame":12},"Concentration of blood triglycerides","Postprandial triglyceride response",null,{"allocation":18,"interventionModel":19,"interventionModelDescription":16,"primaryPurpose":20,"observationalModel":16,"timePerspective":16,"maskingInfo":21},"RANDOMIZED","CROSSOVER","PREVENTION",{"masking":22,"maskingDescription":16,"whoMasked":23},"SINGLE",[24],"INVESTIGATOR","This study will be a single-blind, randomized, crossover acute trial, and all participants will complete an approximately 3-month study period. A total of 19 participants will be recruited and go through all 5 arms (4 intervention and 1 control), with the order randomized. The study will comprise 1 screening visit and 5 test visits, with another 5 compliance visits.",[27,33,39,44,49],{"label":28,"type":29,"description":30,"interventionNames":31},"Salad only","PLACEBO_COMPARATOR","Salad only (no protein)",[32],"Other: Salad only",{"label":34,"type":35,"description":36,"interventionNames":37},"Salad + Chicken","EXPERIMENTAL","Salad with chicken",[38],"Other: Salad + Chicken",{"label":40,"type":35,"description":41,"interventionNames":42},"Salad + Tuna","Salad with tuna",[43],"Other: Salad + Tuna",{"label":45,"type":35,"description":46,"interventionNames":47},"Salad + Egg","Salad with egg",[48],"Other: Salad + Egg",{"label":50,"type":35,"description":51,"interventionNames":52},"Salad + Soybean","Salad with soybeans",[53],"Other: Salad + Soybean",[55,58,61,64,67],{"type":6,"name":28,"description":56,"armGroupLabels":57,"otherNames":16},"Control group, consumption of only salad",[28],{"type":6,"name":34,"description":59,"armGroupLabels":60,"otherNames":16},"Consumption of salad with chicken",[34],{"type":6,"name":40,"description":62,"armGroupLabels":63,"otherNames":16},"Consumption of salad with tuna",[40],{"type":6,"name":45,"description":65,"armGroupLabels":66,"otherNames":16},"Consumption of salad with egg",[45],{"type":6,"name":50,"description":68,"armGroupLabels":69,"otherNames":16},"Consumption of salad with soybean",[50],[71],{"name":72,"affiliation":73,"role":74},"Jung Eun Kim, Ph.D., R.D.","National University of Singapore, Department of Food Science and Technology","PRINCIPAL_INVESTIGATOR",[76],{"name":77,"role":78,"phone":79,"phoneExt":16,"email":80},"Wei Xi Khu, B.Sc.","CONTACT","+65 9359 8952","E0773498@u.nus.edu",[82],{"facility":83,"status":16,"city":84,"state":16,"zip":85,"country":84,"countryCode":86,"cosmosGeoPoint":87,"geoPoint":92,"contacts":93},"NUS, Department of Food Science and Technology, 1 Science Drive 3, Block S13, #03-07, Singapore, 117542","Singapore","117542","SG",{"type":88,"coordinates":89},"Point",[90,91],103.85007,1.28967,{"lat":91,"lon":90},[94,96],{"name":77,"role":78,"phone":95,"phoneExt":16,"email":80},"+65 93598952",{"name":72,"role":74,"phone":16,"phoneExt":16,"email":16},{"type":74,"investigatorFullName":98,"investigatorTitle":99,"investigatorAffiliation":5,"oldNameTitle":16,"oldOrganization":16},"Jung Eun Kim","Associate Professor","100654013","effect-of-co-consuming-different-dietary-protein-sources-with-salad-on-the-bioavailability-of-carotenoids-100654013",false,"NCT07795372","Effect of Co-consuming Different Dietary Protein Sources With Salad on the Bioavailability of Carotenoids","Inclusion Criteria:\n\n1. English-literate and able to give informed consent\n2. Singaporean Adults aged 21 to 45 (inclusive)\n3. Body mass index of 18.5 to 23.0 kg\u002Fm2 (inclusive)\n4. At least 50 kg\n5. Healthy (based on screening results)\n\nExclusion Criteria:\n\n1. Currently participating in another clinical study that involves altering regular diet and\u002For involves consuming a dietary supplement or investigated food product as an intervention\n2. High blood pressure (≥ 140\u002F90 mmHg)\n3. Underlying health conditions that may affect metabolic functions\n4. Consuming carotenoid supplements regularly (i.e., more than three times a week) for the past 3 months, and not willing to discontinue consumption 3 months before and during the study duration\n5. Weight change \\> 3 kg in the past 3 months\n6. Exercising vigorously over the past 3 months (i.e., engaging in high-intensity exercises for more than 3 hours a week, where high-intensity exercises leave one out of breath and unable to talk or sing during the workout)\n7. Current smokers or have quit smoking for less than 5 years\n8. Drinking \\> 2 alcoholic drinks per day (i.e., one drink is defined as either 150 ml of wine, 340 ml of beer\u002Fcider or 45 ml of distilled spirit)\n9. If drinking ≤ 2 alcoholic drinks per day, not willing to stop consumption of alcoholic beverages two days before and on the day of the test visits\n10. Not willing to stop consumption of caffeinated beverages 10 to 12 hours before and on the day of the test visits\n11. Currently on a specialised diet (e.g., vegetarian, vegan, weight loss diet)\n12. Had serious food allergies in the past, or having intolerance, sensitivities or allergies to any of the following: soy\u002Fsoy-derived products, eggs, fish and crustaceans, starch\u002Fstarch-derived products (e.g., rice, corn, wheat, potato), gluten\n13. Disease or impairment of the liver\n14. Currently diagnosed with diabetes, gastrointestinal issues (e.g., lactose intolerance, irritable bowel syndrome), gout and\u002For G6PD deficiency\n15. Taking antibiotics 2 weeks prior to study participation\n16. Taking anti-hypertensive or cholesterol-lowering drugs for less than 3 years unless medically declared by an official doctor to be in stable condition\n17. Poor peripheral venous access based on past experiences with blood drawing\n18. Individuals with pacemaker or related electrical medical devices\n19. Pregnant, lactating, or planning pregnancy in the next 6 months\n20. Have donated blood (whole blood or apheresis) or participated in any other clinical study or trial requiring blood draws within the last 3 months\n21. Clinical anemia (hemoglobin \\\u003C12.0 g\u002FdL in women and \\\u003C13.0 g\u002FdL in men)",true,"ALL","21 Years","45 Years",{"count":111,"type":112},19,"ESTIMATED","INTERVENTIONAL",[115],"NA","The goal of this clinical trial is to learn if different protein types will affect carotenoid responses in humans when co-consumed with salad. The main questions it aims to answer are:\n\n* What are the effect of dietary protein co-consumption with salad on postprandial carotenoid levels in Singapore adults?\n* Do different whole-food protein sources enhance the bioavailability of carotenoids in Singapore adults?\n\nParticipants will:\n\nConsume salad with a form of protein (chicken, tuna, egg, soybean) Have their postprandial plasma carotenoid and triglyceride outcomes evaluated",[118],"Postprandial Carotenoid Response",[120,121],"Plasma carotenoid","Protein Type","NOT_YET_RECRUITING","2026-08-30",{"date":125,"type":126},"2026-09-02","ACTUAL",{"date":128,"type":112},"2026-09",{"date":130,"type":112},"2027-02",{"name":5,"class":6},1]