[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649535":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":32,"locations":43,"responsibleParty":68,"collaborators":37,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":37,"eligibilityCriteria":77,"healthyVolunteers":73,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":37,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":95,"overallStatus":97,"whyStopped":37,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Istanbul University - Cerrahpasa","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"HRT Group","EXPERIMENTAL","Postmenopausal women diagnosed with primary frozen shoulder who are receiving hormone replacement therapy and undergoing the standardized physiotherapy program.",[13],"Procedure: Standardized Physiotherapy Program",{"label":15,"type":16,"description":17,"interventionNames":18},"Non-HRT Group","ACTIVE_COMPARATOR","Postmenopausal women diagnosed with primary frozen shoulder who are not receiving hormone replacement therapy and undergoing the standardized physiotherapy program.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Standardized Physiotherapy Program","A standardized and supervised shoulder physical therapy and rehabilitation program delivered face-to-face in a clinical setting by an expert physiotherapist over 12 weeks (2 sessions per week, 50-60 minutes per session), supplemented by a prescribed home exercise program. The program includes patient education, stretching exercises, active-assisted and active range of motion (ROM) exercises, glenohumeral and scapular mobilization, progressive strengthening exercises, and post-treatment cryotherapy. Exercise progression is individualized based on participants' demographic characteristics, pain levels, progressive overload principles, and subjective feedback. Following each session, participants are routinely monitored for any exercise-related adverse effects.",[9,15],[26,27],"Shoulder Rehabilitation Protocol","Physical Therapy and Exercise Therapy",[29],{"name":30,"affiliation":5,"role":31},"DERYA ÇELİK, PROF.DR.","STUDY_DIRECTOR",[33,39],{"name":34,"role":35,"phone":36,"phoneExt":37,"email":38},"Şükran Acar, Master of Science Candidate","CONTACT","+905346071963",null,"acarsukran58@gmail.com",{"name":40,"role":35,"phone":41,"phoneExt":37,"email":42},"Derya Çelik, Prof. Dr.","+905327940169","derya.celik@iuc.edu.tr",[44],{"facility":45,"status":37,"city":46,"state":47,"zip":48,"country":49,"countryCode":37,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Centro Reformer Pilates Center","Istanbul","Kadikoy","34710","Turkey (Türkiye)",{"type":51,"coordinates":52},"Point",[53,54],28.94966,41.01384,{"lat":54,"lon":53},[57,59,61,63,66],{"name":58,"role":35,"phone":36,"phoneExt":37,"email":38},"Şükran Acar, MSc Candidate",{"name":60,"role":35,"phone":41,"phoneExt":37,"email":42},"Derya Çelik, Prof.Dr.",{"name":58,"role":62,"phone":37,"phoneExt":37,"email":37},"PRINCIPAL_INVESTIGATOR",{"name":64,"role":65,"phone":37,"phoneExt":37,"email":37},"Derya Çelik, PROF.DR.","SUB_INVESTIGATOR",{"name":67,"role":65,"phone":37,"phoneExt":37,"email":37},"Çiğdem Yayla Abide, PROF.DR.",{"type":62,"investigatorFullName":69,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":37,"oldOrganization":37},"Sükran Acar","MSc Student","100649535","effect-of-hormone-replacement-therapy-on-physiotherapy-outcomes-in-postmenopausal-women-with-frozen-shoulder-100649535",false,"NCT07736027","Effect of Hormone Replacement Therapy on Physiotherapy Outcomes in Postmenopausal Women With Frozen Shoulder","The Effects of Hormone Replacement Therapy on Clinical and Functional Outcomes in Postmenopausal Women With Frozen Shoulder","Inclusion Criteria:\n\n* Postmenopausal female patients aged 40 to 60 years.\n* Shoulder pain at rest and during activities of daily living lasting for more than 3 months.\n* Clinical diagnosis of Stage I or Stage II frozen shoulder (adhesive capsulitis).\n* Passive range of motion (ROM) loss of greater than 25% compared to the unaffected shoulder in at least two movement planes (flexion, abduction, internal rotation, or external rotation).\n* Reduced range of motion of less than 50% compared to the unaffected side in at least one movement direction (flexion, abduction, internal rotation, or external rotation).\n* Increased restriction of external and internal rotation during glenohumeral abduction from 45 to 90 degrees.\n\nExclusion Criteria:\n\n* Passive external rotation range of motion of less than 30 degrees (\\\u003C30°).\n* Presence of glenohumeral arthritis confirmed by radiography.\n* History or presence of inflammatory joint disease.\n* History of malignancy or active cancer diagnosis.\n* Previous treatment for the current shoulder condition (e.g., physiotherapy and rehabilitation, intra-articular injections, or surgical intervention).\n* Baseline shoulder pain score of less than 3 (\\\u003C3) on the Numeric Pain Rating Scale (NPRS).","FEMALE","40 Years","60 Years",{"count":82,"type":83},56,"ESTIMATED","INTERVENTIONAL",[86],"NA","The purpose of this study is to compare the effects of a physiotherapy program on pain levels, shoulder range of motion, functional status, pain catastrophizing, perceived change, sleep quality, and quality of life in postmenopausal women diagnosed with frozen shoulder, with and without Hormone Replacement Therapy (HRT). The findings are expected to contribute to personalized treatment planning for postmenopausal women with frozen shoulder and help fill the gap in current literature.",[89,90,91,92,93,94],"Frozen Shoulder","Adhesive Capsulitis","Adhesive Capsulitis of the Shoulder","Hormone Replacement Therapy, Post-Menopausal","Exercise","Physical Therapy",[96],"Frozen Shoulder, Adhesive Capsulitis, Hormone Replacement Therapy, Postmenopause, Physical Therapy, Rehabilitation, Pain Catastrophizing, Range of Motion","NOT_YET_RECRUITING","2026-07-28",{"date":100,"type":101},"2026-07-30","ACTUAL",{"date":103,"type":83},"2026-09-01",{"date":105,"type":83},"2027-10-01",{"name":5,"class":6},1]