[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100652062":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":59,"collaborators":26,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":26,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":26,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Izmir Katip Celebi University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Clark Vestibuloplasty + Oxidized Regenerated Cellulose","EXPERIMENTAL","Participants in this arm will undergo standard Clark vestibuloplasty. In addition, oxidized regenerated cellulose (Reoxcel Sigma Knit) will be applied over the surgical wound in a double layer and secured with sutures.",[13],"Device: Oxidized Regenerated Cellulose (ORC)",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard Clark Vestibuloplasty","ACTIVE_COMPARATOR","Participants in this arm will undergo standard Clark vestibuloplasty. Following surgery, the exposed gingival wound surface will be covered with a periodontal dressing (Coe-Pak) without the application of oxidized regenerated cellulose.",[19],"Device: Periodontal Dressing",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Oxidized Regenerated Cellulose (ORC)","Oxidized regenerated cellulose (Reoxcel Sigma Knit, 5 × 7.5 cm) will be applied in a double layer over the exposed gingival wound surface following standard Clark vestibuloplasty. The material will be secured with 4-0 polyglycolide-lactide sutures using crossed and simple suturing techniques.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Periodontal Dressing","Periodontal dressing (Coe-Pak) will be applied over the exposed gingival wound surface following standard Clark vestibuloplasty. The dressing will cover the surgical site during the postoperative healing period.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Can Berk Arığ","CONTACT","+90 534 060 64 57","canberkarig@gmail.com",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":26,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"İzmir Katip Çelebi University","RECRUITING","Izmir","Çiğli","35620","Turkey (Türkiye)",{"type":46,"coordinates":47},"Point",[48,49],27.13838,38.41273,{"lat":49,"lon":48},[52,53,56],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},{"name":54,"role":55,"phone":26,"phoneExt":26,"email":26},"Can Berk Arığ, Research Assistant","PRINCIPAL_INVESTIGATOR",{"name":57,"role":58,"phone":26,"phoneExt":26,"email":26},"Mehmet Sağlam, Professor","SUB_INVESTIGATOR",{"type":55,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Can Berk Arig","Research Assistant","100652062","effect-of-oxidized-regenerated-cellulose-on-vestibular-sulcus-depth-after-clark-vestibuloplasty-100652062",false,"NCT07767682","Effect of Oxidized Regenerated Cellulose on Vestibular Sulcus Depth After Clark Vestibuloplasty","The Effect of Using Oxidized Regenerated Cellulose Material in Addition to the Standard Clark Vestibuloplasty Technique on Increasing Vestibular Sulcus Depth","Inclusion Criteria:\n\n* Systemically healthy\n* Non-smoker\n* Insufficient vestibular sulcus depth\n* No regular medication use\n* Age 18 years or older\n* No previous vestibuloplasty in the same region\n* Not pregnant or breastfeeding\n* Willing to participate and able to provide written informed consent\n\nExclusion Criteria:\n\n* Presence of a systemic disease\n* Regular use of systemic medication\n* Pregnancy or lactation\n* Smoking or alcohol use\n* Previous vestibuloplasty in the same region","ALL","18 Years","70 Years",{"count":73,"type":74},36,"ESTIMATED","INTERVENTIONAL",[77],"NA","This randomized controlled clinical study will evaluate whether the use of oxidized regenerated cellulose (Reoxcel Sigma Knit) in addition to standard Clark vestibuloplasty improves vestibular sulcus depth and patient comfort in individuals with insufficient vestibular depth. A total of 36 participants will be assigned to either Clark vestibuloplasty with oxidized regenerated cellulose or standard Clark vestibuloplasty with periodontal dressing. Vestibular sulcus depth and keratinized gingival tissue will be assessed before treatment and at 1 and 3 months after surgery. Postoperative pain and analgesic use will also be evaluated during the first 7 days after surgery.",[80],"Insufficient Vestibular Sulcus Depth",[82,83,84,85,86],"vestibuloplasty","Clark vestibuloplasty","oxidized regenerated cellulose","vestibular sulcus depth","keratinized gingiva","2026-08-12",{"date":89,"type":90},"2026-08-17","ACTUAL",{"date":92,"type":90},"2026-04-09",{"date":94,"type":74},"2027-07-30",{"name":5,"class":6},1]