[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650053":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":31,"centralContacts":37,"locations":31,"responsibleParty":43,"collaborators":31,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":31,"eligibilityCriteria":53,"healthyVolunteers":49,"sex":54,"minAge":55,"maxAge":31,"enrollmentInfo":56,"targetDuration":31,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":31,"overallStatus":65,"whyStopped":31,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":31},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"100mg Diclofenac potassium","EXPERIMENTAL","Preoperative single dose of diclofenac potassium 100mg",[13],"Drug: Diclofenac potassium 100mg",{"label":15,"type":16,"description":17,"interventionNames":18},"50mg Diclofenac potassium","ACTIVE_COMPARATOR","Preoperative single dose of diclofenac potassium 50mg",[19],"Drug: Diclofenac potassium 50mg",{"label":21,"type":22,"description":23,"interventionNames":24},"Placebo","PLACEBO_COMPARATOR","Preoperative placebo",[25],"Drug: Placebo",[27,32,35],{"type":28,"name":29,"description":11,"armGroupLabels":30,"otherNames":31},"DRUG","Diclofenac potassium 100mg",[9],null,{"type":28,"name":33,"description":17,"armGroupLabels":34,"otherNames":31},"Diclofenac potassium 50mg",[15],{"type":28,"name":21,"description":23,"armGroupLabels":36,"otherNames":31},[21],[38],{"name":39,"role":40,"phone":41,"phoneExt":31,"email":42},"Ameena K Bagunaid","CONTACT","00201017200542","ameena.omar@dentistry.cu.edu.eg",{"type":44,"investigatorFullName":45,"investigatorTitle":46,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"PRINCIPAL_INVESTIGATOR","Ameena Khaled Omar Bagunaid","Postgraduate student","100650053","effect-of-preoperative-diclofenac-potassium-dose-on-endodontic-pain-100650053",false,"NCT07743372","Effect of Preoperative Diclofenac Potassium Dose on Endodontic Pain","Effect of Diclofenac Potassium Premedication Dose on Anesthetic Success and Post-operative Pain in Mandibular Molars With Symptomatic Irreversible Pulpitis: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients with symptomatic irreversible pulpitis.\n* Patients with moderate to severe pain.\n* Mandibular molars\n* Patients with the ability to understand and use the pain scale\n\nExclusion Criteria:\n\n* Patients allergic to any medication or material to be used in the study.\n* Pregnant and lactating females.\n* Patients taking medications affecting pain perception in the last 12 hours.\n* Patients having more than one symptomatic molar in the same quadrant.\n* Patients with contributory medical history (ASA I or II).","ALL","18 Years",{"count":57,"type":58},90,"ESTIMATED","INTERVENTIONAL",[61],"NA","The aim of this study is to assess the effect of different doses of diclofenac potassium premedication (100mg vs 50mg) on anesthetic success of 4% articaine buccal infiltration and post-operative pain as compared to placebo in mandibular molars with symptomatic irreversible pulpitis.",[64],"Symptomatic Irreversible Pulpitis (SIP)","NOT_YET_RECRUITING","2026-07-29",{"date":68,"type":69},"2026-08-03","ACTUAL",{"date":71,"type":58},"2026-08",{"date":73,"type":58},"2028-02",{"name":5,"class":6}]