[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100560404":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":26,"locations":36,"responsibleParty":57,"collaborators":54,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":21,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":54,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":39,"whyStopped":54,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"University of Padova","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Active supplement","EXPERIMENTAL","Treatment: the capsules contains Grape Seed Extract GSE-0001- Proanthocyanidins \\\u003C95%)",[13],"Biological: Grape Seed Extracts",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"BIOLOGICAL","Grape Seed Extracts","2 capsules\u002Fday for 8 weeks",[9],[21],"EcoVitis",[23],{"name":24,"affiliation":5,"role":25},"Edoardo V Savarino, MD, PhD","PRINCIPAL_INVESTIGATOR",[27,33],{"name":28,"role":29,"phone":30,"phoneExt":31,"email":32},"Edoardo V. Savarino, MD; PhD","CONTACT","0498218720","0039","edoardo.savarino@unipd.it",{"name":34,"role":29,"phone":30,"phoneExt":31,"email":35},"Sonia Facchin, PhD","sonia.facchin@unipd.it",[37],{"facility":38,"status":39,"city":40,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Edoardo Vincenzo Savarino","RECRUITING","Padua","35128","Italy","IT",{"type":45,"coordinates":46},"Point",[47,48],11.88586,45.40797,{"lat":48,"lon":47},[51,55],{"name":52,"role":29,"phone":53,"phoneExt":54,"email":32},"Edoardo V. Savarino","+39.049.8217749",null,{"name":56,"role":29,"phone":54,"phoneExt":54,"email":35},"Sonia Facchin",{"type":58,"investigatorFullName":54,"investigatorTitle":54,"investigatorAffiliation":54,"oldNameTitle":54,"oldOrganization":54},"SPONSOR","100560404","effect-of-procyanidins-in-leaky-gut-repairing-in-ibd-100560404",false,"NCT06576700","Effect of Procyanidins in Leaky Gut Repairing in IBD","Effect of Procyanidins in the Leaky Gut Repairing Associated with Inflammatory Bowel Disease","Inclusion Criteria:\n\n* Diagnosis of UC confirmed by clinical, endoscopic and histopathological evidence. Disease in remission phase confirmed by clinical, endoscopic and histopathological evidence.\n\n  * Age between 18 and 75 years old\n  * Ability of subject to participate fully in all aspects of this clinical trial.\n\nExclusion Criteria:\n\n* ● Patients that have active UC, determined by clinical, endoscopic and histopathological evidences\n\n  * Known diagnosis of CD, indeterminate colitis, ischemic colitis, radiation colitis, diverticular disease associated with colitis or microscopic colitis\n  * Positive stool culture for active C. difficile\n  * Pregnant women\n  * Patients under antibiotic and\u002For probiotic treatment within 10 days prior to Visit 1.","ALL","18 Years","80 Years",{"count":70,"type":71},25,"ESTIMATED","INTERVENTIONAL",[74],"NA","The goal of this clinical trial is to learn if the Grape Seed Extract Ecovitis, featuring low monomeric catechins content and a high concentration of oligo-polymeric procyanidins, could modulate the Gut Microbiota composition of Ulcerative Colitis patients during the remission phase. The main questions it aims to answer are:\n\nDoes Ecovitis improve the microbiota composition in patients with Ulcerative colitis? Is the intestinal permeability affected? What about the variation in the quality of life?\n\nParticipants will:\n\nTake 2 capsules\u002Fday of Ecovitis for eight weeks Visit the clinic two times for checkups, serum collection, and Questionaire.",[77],"Ulcerative Colitis in Remission",[79,80,81],"Microbiota","proanthocyanidine","polyphenols","2024-09-03",{"date":84,"type":85},"2024-09-19","ACTUAL",{"date":87,"type":85},"2024-06-15",{"date":89,"type":71},"2026-06-12",{"name":5,"class":6},1]