[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100652106":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":23,"centralContacts":27,"locations":22,"responsibleParty":36,"collaborators":22,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":22,"eligibilityCriteria":45,"healthyVolunteers":41,"sex":46,"minAge":47,"maxAge":48,"enrollmentInfo":49,"targetDuration":22,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":62,"whyStopped":22,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":70,"locationsCount":22},{"fullName":5,"class":6},"Cairo University","OTHER",[8,13],{"label":9,"type":10,"description":9,"interventionNames":11},"Prophylaxis paste with desensitizing agent","EXPERIMENTAL",[12],"Other: Treatment",{"label":14,"type":15,"description":14,"interventionNames":16},"Prophylaxis paste without desensitizing agent","PLACEBO_COMPARATOR",[12],[18],{"type":6,"name":19,"description":20,"armGroupLabels":21,"otherNames":22},"Treatment","Prophylaxis paste will be applied to all tooth surfaces using a prophy cup attached to a low-speed contra-angle handpiece. The paste will remain on the teeth for the duration specified in the manufacturer's instructions for use before being rinsed away.",[9,14],null,[24],{"name":25,"affiliation":5,"role":26},"Zeinab O Tolba, Associate Professor","PRINCIPAL_INVESTIGATOR",[28,32],{"name":25,"role":29,"phone":30,"phoneExt":22,"email":31},"CONTACT","+2 01222308738","zeinab.omar@dentistry.cu.edu.eg",{"name":33,"role":29,"phone":34,"phoneExt":22,"email":35},"Possy M Abd El Aziz, Associate Professor","+2 01061023968","possy.moustafa@dentistry.cu.edu.eg",{"type":26,"investigatorFullName":37,"investigatorTitle":38,"investigatorAffiliation":5,"oldNameTitle":22,"oldOrganization":22},"Zeinab Omar Tolba","Associate Professor, Conservative Dentistry Department, Faculty of Dentistry, Cairo University","100652106","effect-of-prophylaxis-pastes-with-and-without-desensitizing-agents-prior-to-in-office-bleaching-100652106",false,"NCT07770373","Effect of Prophylaxis Pastes With and Without Desensitizing Agents Prior to In-office Bleaching","Effect of Prophylaxis Pastes With and Without Desensitizing Agents Prior to In-office Bleaching on Color Change and Tooth Sensitivity: Randomized Clinical Trial","Inclusion Criteria:\n\n* Patients who have discolored teeth, minimum of 20 natural teeth, good oral hygiene, do not have any systemic disease.\n\nExclusion Criteria:\n\n* Patients who have extensive prosthesis or restoration, tetracycline discoloration or fluorosis, endodontically treated teeth or gingival recession, smokers, periodontal disease, pregnant or lactating.","ALL","18 Years","45 Years",{"count":50,"type":51},38,"ESTIMATED","INTERVENTIONAL",[54],"NA","To evaluate the effect of prophylaxis pastes with and without desensitizing agents prior to in-office bleaching on color change and tooth sensitivity.",[57],"Discolored Teeth",[59,60,61],"bleaching","desensitizing agents","discoloration","NOT_YET_RECRUITING","2026-08-13",{"date":65,"type":66},"2026-08-18","ACTUAL",{"date":68,"type":51},"2026-08",{"date":68,"type":51},{"name":5,"class":6}]