[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100617778":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":41,"responsibleParty":59,"collaborators":26,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":43,"acronym":26,"eligibilityCriteria":66,"healthyVolunteers":67,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":26,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":26,"overallStatus":44,"whyStopped":26,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"The First People's Hospital of Lianyungang","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Tegilerdine group","EXPERIMENTAL","Administer 20-50µ\u002Fkg of Tegilerdine before induction of general anesthesia, and record the patient's coughing episodes 2 minutes after administration. Then proceed with anesthesia induction.",[13],"Drug: Tegilerdine",{"label":15,"type":16,"description":17,"interventionNames":18},"Sufentanil group","ACTIVE_COMPARATOR","Administer sufentanil 0.2-0.4 µg\u002Fkg before the induction of general anesthesia, and record the patient's coughing episodes 2 minutes after administration. Then proceed with anesthesia induction.",[19],"Drug: Sufentanil",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Tegilerdine","Inject Tegilerdine in the induction of general anesthesia",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sufentanil","Inject Sufentanil in the induction of general anesthesia",[15],[32],{"name":33,"affiliation":34,"role":35},"Xiaobao Zhang, Doctor","Xuzhou Medical University Affiliated Hospital of Lianyungang: Lianyungang No 1 People's Hospital","STUDY_DIRECTOR",[37],{"name":33,"role":38,"phone":39,"phoneExt":26,"email":40},"CONTACT","18961322507","hotdog100@163.coom",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":26,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"The Affiliated Lianyungang Hospital of Xuzhou Medical University","RECRUITING","Lianyungang","Jiangsu","China","CN",{"type":50,"coordinates":51},"Point",[52,53],119.21556,34.59845,{"lat":53,"lon":52},[56,57],{"name":33,"role":38,"phone":39,"phoneExt":26,"email":26},{"name":58,"role":38,"phone":26,"phoneExt":26,"email":26},"ALHOXM",{"type":60,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100617778","effect-of-tegileridine-versus-sufentanil-as-analgesic-components-on-opioid-induced-cough-during-anesthesia-induction-100617778",false,"NCT07323043","Effect of Tegileridine Versus Sufentanil as Analgesic Components on Opioid-Induced Cough During Anesthesia Induction","Inclusion Criteria:\n\n1. Age between 18 and 65 years, 18 ≤ BMI (kg\u002Fm²) ≤ 30;\n2. ASA grade I \\~ III;\n3. Scheduled elective surgery under general anesthesia with tracheal intubation.\n\nExclusion Criteria:\n\n1. Patients with chronic cough (cough lasting \\>8 weeks) or asthma;\n2. Patients with a history of allergy to the drugs used during the study;\n3. Patients with severe cardiovascular disease, intracranial lesions, eye lesions, or lung lesions.",true,"ALL","18 Years","65 Years",{"count":72,"type":73},190,"ESTIMATED","INTERVENTIONAL",[76],"NA","In patients undergoing general anesthesia with planned tracheal intubation , a prospective, randomized, controlled study was conducted to record the occurrence of cough 2 minutes after injection of Sufentanil or Tegilerdine. The cough was graded based on the frequency and duration: Grade I, no cough; Grade II, a single mild cough; Grade III, multiple coughs with duration \\\u003C1 second; Grade IV, continuous coughing with a duration \\>15 seconds.",[79],"General Anesthetic Drug Adverse Reaction","2026-07-07",{"date":82,"type":83},"2026-07-08","ACTUAL",{"date":85,"type":83},"2026-01-15",{"date":87,"type":73},"2026-10-13",{"name":5,"class":6},1]