[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100658624":3},{"organization":4,"outcomesModule":7,"designInfo":27,"detailedDescription":26,"studyPopulation":26,"armGroups":37,"interventions":49,"overallOfficials":26,"centralContacts":26,"locations":26,"responsibleParty":59,"collaborators":26,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":67,"acronym":26,"eligibilityCriteria":68,"healthyVolunteers":65,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":26,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":26,"overallStatus":82,"whyStopped":26,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":26},{"fullName":5,"class":6},"Al-Zaytoonah University of Jordan","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":22,"otherOutcomes":26},[9,13,16,19],{"measure":10,"description":11,"timeFrame":12},"PaCO2","partial pressure of carbon dioxide in arterial blood, measuring how effectively the lungs eliminate carbon dioxide","Will be assessed at baseline (day 1) pre the intervention of the 1st session and (day 6) post the intervention of the 12th session.",{"measure":14,"description":15,"timeFrame":12},"PaO2","partial pressure of oxygen dissolved in arterial blood plasma, measured through an Arterial Blood Gas (ABG) test.",{"measure":17,"description":18,"timeFrame":12},"SaO2","the percentage of oxygen-saturated hemoglobin relative to total hemoglobin in arterial blood, typically measured via an invasive arterial blood gas (ABG) analysis with normal values ranging from 95% to 99%",{"measure":20,"description":21,"timeFrame":12},"PaO2\u002FFiO2 (P\u002FF)","a clinical metric used to evaluate oxygenation efficiency and diagnose the severity of acute hypoxemic respiratory failure or Acute Respiratory Distress Syndrome (ARDS).",[23],{"measure":24,"description":25,"timeFrame":12},"Pulmonary compliance","the change in lung volume divided by the change in pressure (Δ V \u002F Δ P). Higher compliance means the lungs stretch easily; lower compliance means they are stiff and harder to inflate",null,{"allocation":28,"interventionModel":29,"interventionModelDescription":26,"primaryPurpose":30,"observationalModel":26,"timePerspective":26,"maskingInfo":31},"RANDOMIZED","PARALLEL","PREVENTION",{"masking":32,"maskingDescription":26,"whoMasked":33},"TRIPLE",[34,35,36],"PARTICIPANT","CARE_PROVIDER","INVESTIGATOR",[38,44],{"label":39,"type":40,"description":41,"interventionNames":42},"ventilator hyperinflation from lateral decubitus position","EXPERIMENTAL","This group will receive Ventilator hyperinflation in lateral decubitus position (affected lung uppermost) and Conventional respiratory physiotherapy",[43],"Device: Ventilator hyperinflation",{"label":45,"type":40,"description":46,"interventionNames":47},"Manual hyperinflation for Lateral decubitus position","This group will receive manual hyperinflation in Lateral decubitus position and Conventional respiratory physiotherapy",[48],"Device: Manual hyperinflation",[50,55],{"type":51,"name":52,"description":53,"armGroupLabels":54,"otherNames":26},"DEVICE","Ventilator hyperinflation","a therapeutic technique used by clinicians (Manual or Ventilator Hyperinflation) to clear secretions and recruit collapsed lung tissue, or an inadvertent complic",[39],{"type":51,"name":56,"description":57,"armGroupLabels":58,"otherNames":26},"Manual hyperinflation","a respiratory therapy technique that uses a manual resuscitation bag to deliver larger-than-normal, controlled breaths to clear airway secretions and reopen collapsed lung areas",[45],{"type":60,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Mohamed Saied Zidan","Assistant professor doctor","100658624","effect-of-ventilator-hyperinflation-combined-with-body-positioning-on-arterial-blood-gases-in-patients-with-ventilator-associated-pneumonia--a-randomized-controlled-trial-100658624",false,"NCT07854730","Effect of Ventilator Hyperinflation Combined With Body Positioning on Arterial Blood Gases In Patients With Ventilator-Associated Pneumonia : A Randomized Controlled Trial","Inclusion Criteria:\n\n* Mechanically ventilated patients ≥ 48 hours\n* Diagnosed with VAP (clinical + chest X-ray)\n* Age: 40-60 years\n* Hemodynamically stable\n* Unilateral lung involvement\n\nExclusion Criteria:\n\n* Bilateral lung disease\n* Unstable cardiovascular conditions\n* Contraindications to positioning\n* Re-intubation cases\n* Presence of pneumothorax or air leak","ALL","40 Years","60 Years",{"count":73,"type":74},40,"ESTIMATED","INTERVENTIONAL",[77],"NA","This study aims to evaluate the effect of ventilator hyperinflation combined with body positioning on arterial blood gases in patients with ventilator-associated pneumonia. Forty-two mechanically ventilated patients will be randomly assigned into two groups receiving the intervention in either supine or lateral decubitus positions. Arterial blood gases will be assessed over a 6-day intervention period. The findings are expected to provide evidence regarding the optimal positioning strategy to enhance the effectiveness of ventilator hyperinflation in improving gas exchange in critically ill patients.",[80,81],"Ventilator Associated Bacterial Pneumonia (VABP)","Critical Illness","NOT_YET_RECRUITING","2026-09-27",{"date":85,"type":86},"2026-10-02","ACTUAL",{"date":88,"type":74},"2026-10-05",{"date":90,"type":74},"2026-11-15",{"name":5,"class":6}]