[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100515123":3},{"organization":4,"outcomesModule":7,"designInfo":35,"detailedDescription":34,"studyPopulation":34,"armGroups":41,"interventions":59,"overallOfficials":70,"centralContacts":75,"locations":82,"responsibleParty":105,"collaborators":34,"id":108,"slug":109,"hasResults":110,"nctId":111,"briefTitle":112,"officialTitle":113,"acronym":114,"eligibilityCriteria":115,"healthyVolunteers":116,"sex":117,"minAge":118,"maxAge":34,"enrollmentInfo":119,"targetDuration":34,"studyType":122,"phases":123,"briefSummary":125,"conditions":126,"keywords":130,"overallStatus":85,"whyStopped":34,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":139,"startDateStruct":142,"completionDateStruct":144,"leadSponsor":146,"locationsCount":147},{"fullName":5,"class":6},"Fondazione Don Carlo Gnocchi ETS","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":34},[9],{"measure":10,"description":11,"timeFrame":12},"Six Minute Walking Test (6MWT) distance in meters","Assess distance in meters, determined by the Six Minute Walking Test (6MWT) in the Nordic Walking (NW) group compared to the Standard Rehabilitation (SR) and Control (CG) Groups at baseline (T0), the end of the rehabilitation treatment (T1), and after 3 months of observation (T2)","An average of 6 months",[14,18,21,24,28,31],{"measure":15,"description":16,"timeFrame":17},"Adherence","Monitoring of adherence to the intervention considering the number of sessions of the treatment \\[Nordic Walking (NW); Standard Rehabilitation (SR) or Control Group (CG) intervention\\] attended during the 3 months.","Through intervention completion, an average of 3 months",{"measure":19,"description":20,"timeFrame":12},"Anxiety","To verify the effectiveness of the interventions in reducing the levels of anxiety as detected by The Generalized Anxiety Disorder Scale (GAD-7) in the Nordic Walking (NW) group compared to the Standard Rehabilitation (SR) and Control (CG) Groups at baseline (T0), the end of the rehabilitation treatment (T1), and after 3 months of observation (T2). The following cut-offs correlate with level of anxiety severity: Score 0-4: Minimal Anxiety; Score 5-9: Mild Anxiety; Score 10-14: Moderate Anxiety; Score greater than 15: Severe Anxiety (Spitzer et al., 2006).",{"measure":22,"description":23,"timeFrame":12},"Depression","To verify the effectiveness of the interventions in reducing the levels of depression as detected by The Patient Health Questionnaire-9 (PHQ-9) in the Nordic Walking (NW) group compared to the Standard Rehabilitation (SR) and Control (CG) Groups at baseline (T0), the end of the rehabilitation treatment (T1), and after 3 months of observation (T2). Regarding severity, PHQ-9 comprises five categories, where a cut-off point of 0-4 indicates no depressive symptoms, 5-9 mild depressive symptoms, 10-14 moderate depressive symptoms, 15-19 moderately-severe depressive symptoms, and 20-27 severe depressive symptoms (Kroenke and Spitzer, 2002).",{"measure":25,"description":26,"timeFrame":27},"The Short Form Health Survey 12 (SF-12)","To verify the effectiveness of the interventions in improving the levels of Quality of Life detected thanks to The Short Form Health Survey 12 (SF-12) (Ware et al., 2000) in the Nordic Walking (NW) group compared to the Standard Rehabilitation (SR) and Control (CG) Groups at baseline (T0), the end of the rehabilitation treatment (T1), after 3 months of observation (T2), 12 months (T3).","An average of 12 months",{"measure":29,"description":30,"timeFrame":27},"Variation in Body Mass Index (BMI)","To verify the effectiveness of the interventions in improving the Body Mass Index (BMI) in the Nordic Walking (NW) group compared to the Standard Rehabilitation (SR) and Control (CG) Groups at baseline (T0), the end of the rehabilitation treatment (T1), after 3 months of observation (T2), 12 months (T3).\n\nAn improvement of at least 10% in BMI is considered significant.",{"measure":32,"description":33,"timeFrame":12},"Peak Oxygen Uptake (VO2)","Assess increasing in Peak Oxygen Uptake (VO2) in the Nordic Walking (NW) group compared to the Standard Rehabilitation (SR) and Control (CG) Groups group at baseline (T0), the end of the rehabilitation treatment (T1), and after 3 months of observation (T2)",null,{"allocation":36,"interventionModel":37,"interventionModelDescription":38,"primaryPurpose":6,"observationalModel":34,"timePerspective":34,"maskingInfo":39},"RANDOMIZED","PARALLEL","This is a single-center, randomized controlled intervention study with three parallel arms (NW=Nordic Walking, SR=standard rehabilitation and CG=control group), open label.",{"masking":40,"maskingDescription":34,"whoMasked":34},"NONE",[42,48,54],{"label":43,"type":44,"description":45,"interventionNames":46},"Nordic Walking (NW)","EXPERIMENTAL","Nordic walking is a form of physical activity that originated in Finland and has gained popularity worldwide. It involves walking with the use of specially designed poles that resemble ski poles. This activity engages both the upper and lower body, making it a full-body workout. In summary, Nordic walking offers several benefits for cardiovascular individuals with Type II diabetes and those who are obese or overweight. These benefits include improved heart and lung function, better blood glucose control, weight management, low joint impact, muscle strengthening, improved balance and posture, and social engagement. However, it is important to consult with a healthcare provider before starting any new exercise program to ensure it is safe and suitable for individual health conditions and goals. Regular monitoring and adjustments by healthcare professionals can help optimize the benefits and ensure ongoing progress.",[47],"Other: Nordic Walking (NW)",{"label":49,"type":50,"description":51,"interventionNames":52},"Standard Rehabilitation (SR)","ACTIVE_COMPARATOR","A standard rehabilitation program for cardiovascular individuals with Type II diabetes and obesity\u002Foverweight typically involves a combination of cardiovascular exercise, strength training, and education on lifestyle modifications. The program is prescribed by a cardiologist and supervised by physiotherapists or exercise specialists. It includes an initial assessment to determine exercise parameters, cardiovascular exercise to improve heart function and manage blood glucose levels, strength training to increase muscle mass and aid in weight management, education on nutrition and lifestyle modifications, and progress tracking and monitoring to optimize outcomes. These programs provide benefits such as improved cardiovascular fitness, better blood glucose control, weight management, enhanced muscle strength, and overall well-being.",[53],"Other: Standard Rehabilitation (SR)",{"label":55,"type":6,"description":56,"interventionNames":57},"Control Group (CG)","Cardiological counseling for cardiovascular individuals with Type II diabetes and obesity\u002Foverweight often includes recommendations for unsupervised aerobic physical activity. This type of counseling typically involves a cardiologist providing guidelines and recommendations for safe and effective exercise routines. In summary, it involves an initial assessment to determine exercise capacity and precautions. The cardiologist prescribes specific guidelines for unsupervised aerobic physical activity, including the type, frequency, intensity, and duration of exercise sessions. Safety considerations are provided. The benefits of unsupervised aerobic physical activity include improved cardiovascular health, enhanced blood glucose control, weight management, psychological well-being, and increased energy and stamina.",[58],"Other: Cardiological Counselling (CC)",[60,63,66],{"type":6,"name":43,"description":61,"armGroupLabels":62,"otherNames":34},"The experimental group will carry out NW sessions three times a week for 12 weeks, supervised by a NW instructor and under the control of a cardiologist. The duration of each NW session will initially be 90 minutes: 10 minutes of warm-up, 60 of NW, and 15 minutes of cool-down. The intensity of the course will be gradually increased each week, starting at 70 to 85% of the heart rate (HR) reserve. It will also receive indications relating to a balanced diet plan which proposes a moderate (300-400 KCal) daily caloric restriction concerning the usual caloric expenditure, estimated based on initial body composition measurements.",[43],{"type":6,"name":49,"description":64,"armGroupLabels":65,"otherNames":34},"The second group will follow a standard rehabilitation program with an initial cardiological prescription and supervised by physiotherapists, carried out 5 days a week with sessions lasting 40 minutes, including 5 minutes of warm-up up), 30 min of aerobic physical activity on a conveyor belt or cycle ergometer and 5 minutes of cooling down (cool down). The intensity of your aerobic activity will gradually increase each week, starting at 70 to 85% of HR reserve. It will also receive indications relating to a balanced diet plan which proposes a moderate (300-400 KCal) daily caloric restriction concerning the usual caloric expenditure, estimated based on initial body composition measurements.",[49],{"type":6,"name":67,"description":68,"armGroupLabels":69,"otherNames":34},"Cardiological Counselling (CC)","The third group of participants will receive cardiological counselling with indications of unsupervised aerobic physical activity. The group will also receive indications relating to a balanced diet plan which proposes a moderate (300-400 KCal) daily caloric restriction concerning the usual caloric expenditure, estimated based on initial body composition measurements.",[55],[71],{"name":72,"affiliation":73,"role":74},"Anna Torri, MD","IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy","PRINCIPAL_INVESTIGATOR",[76],{"name":77,"role":78,"phone":79,"phoneExt":80,"email":81},"Nuccia Morici, MD, Ph.D.","CONTACT","3206359064","0039","nmorici@dongnocchi.it",[83],{"facility":84,"status":85,"city":86,"state":34,"zip":87,"country":88,"countryCode":89,"cosmosGeoPoint":90,"geoPoint":95,"contacts":96},"IRCCS Fondazione Don Carlo Gnocchi","RECRUITING","Milan","20148","Italy","IT",{"type":91,"coordinates":92},"Point",[93,94],9.18951,45.46427,{"lat":94,"lon":93},[97,100,104],{"name":72,"role":78,"phone":98,"phoneExt":80,"email":99},"3477408748","atorri@dongnocchi.it",{"name":101,"role":78,"phone":102,"phoneExt":80,"email":103},"Eleonora Volpato, Psy.D, Ph.D.","3293782692","evolpato@dongnocchi.it",{"name":72,"role":74,"phone":34,"phoneExt":34,"email":34},{"type":74,"investigatorFullName":106,"investigatorTitle":107,"investigatorAffiliation":5,"oldNameTitle":34,"oldOrganization":34},"Nuccia Morici","MD, Ph.D.","100515123","effectiveness-of-a-rehabilitation-treatment-with-nordic-walking-in-obese-or-overweight-patients-100515123",false,"NCT05987410","EffectiVenEss of a Rehabilitation Treatment With Nordic Walking in obEse or oveRweight Patients","EffectiVenEss of a Rehabilitation Treatment With Nordic Walking in obEse or oveRweight Diabetic patiEnts With Cardiovascular Disease. The VENERE Study","VENERE","Inclusion Criteria:\n\n\\- overweight \\[Body Mass Index (BMI) ≥ 27 kg\u002Fm2\\] or obese (BMI ≥30 kg\u002Fm2) adult patients with diabetes mellitus and with a recent cardiovascular event and\u002For coronary revascularization in the previous three months\n\nExclusion Criteria:\n\n* inability to walk independently and constantly;\n* acute joint or spine pathologies that make movement impossible;\n* the presence of dementia as approved by consultation of the patient's medical record and\u002For administration of the Montreal Cognitive Assessment (MOCA) test ≤ 15.5 (Nasreddine et al., 2005);\n* chemotherapy 6 months before surgery;\n* advanced renal failure;\n* acute cardiovascular event \\\u003C 3 months (unstable angina, AMI with FE \\\u003C40%, arrhythmias, valvular disease, intracerebral\u002Fsubdural haemorrhage, uncontrolled AI);\n* home oxygen therapy and Non-Invasive Ventilation (NIV) \\[excluding Continuous Positive Airway Pressure (CPAP)\\].",true,"ALL","18 Years",{"count":120,"type":121},105,"ESTIMATED","INTERVENTIONAL",[124],"NA","Nordic Walking (NW) is a biomechanically correct walking technique that originated in Finland in the 1930s as an off-season training method for cross-country skiers. In the NW, the use of special sticks is combined with \"conventional\" walking: this involves a greater caloric expenditure, with an energy consumption higher by 20-30% compared to walking without sticks, and also toning of the upper part of the body, in particular triceps, shoulders and back, and the involvement of about 90% of the body's muscles, while maintaining a reduced load on ligaments and joints (Baek \\& Ha, 2021). The NW acts simultaneously and effectively on different components of fitness: coordination, endurance, strength, and mobility. It does not require sudden accelerations and is based on a technique that is easy to learn (with the help of an instructor), especially as regards maintaining correct posture. Finally, in addition to the cardiovascular benefits, NW has also been shown to effectively reduce the risk of falls in the elderly. The study is a single-center, randomized controlled trial (RCT), with a three-parallel-arm design, open-label. The primary objective is to evaluate the efficacy (in terms of cardiovascular performance), safety, and adherence (in terms of dropout rate) to the exercise prescription after 6 and 12 months follow-up of a 3-month NW intervention compared with standard rehabilitation training (SR, 3 months) in obese\u002Foverweight diabetic patients with cardiovascular (CV) complications. The study will enroll in parallel a control group that can access only generic cardiological counseling with a prescription for unsupervised home exercise.",[127,128,129],"Cardiovascular Diseases","Diabete Type 2","Overweight and Obesity",[43,131,132,133,134,135,136,137],"cardiovascular disease","diabetes Type II","overweight","obesity","Six Minute Walking Test (6MWT)","adherence","rehabilitation","2026-09-01",{"date":140,"type":141},"2026-09-03","ACTUAL",{"date":143,"type":141},"2023-12-01",{"date":145,"type":121},"2028-12-31",{"name":5,"class":6},1]