[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646874":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":26,"centralContacts":35,"locations":41,"responsibleParty":59,"collaborators":26,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":26,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":26,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":83,"overallStatus":88,"whyStopped":26,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"University of Medicine and Pharmacy at Ho Chi Minh City","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Electroacupuncture (Xuanzhong, Tongli) + Basic Treatment with Speech therapy","EXPERIMENTAL","Participants receive daily electroacupuncture at Xuanzhong (GB39) and Tongli (HT5) acupoints (2 Hz, 2mA, 20-minute retention) for 5 days per week over a 4-week period. This is combined with the hospital's basic treatment protocol, which includes standard medical management (blood pressure, lipid, and glucose control; antiplatelet therapy) and 30 minutes of daily speech therapy (5 days per week).",[13,14],"Other: Electroacupuncture","Other: Basic treatment + Speech therapy",{"label":16,"type":17,"description":18,"interventionNames":19},"Sham Electroacupuncture + Basic Treatment with Speech therapy","SHAM_COMPARATOR","Participants receive daily sham electroacupuncture at non-acupoint locations (1 cm from Xuanzhong and Tongli, 0 mA intensity) for 5 days per week over a 4-week period. This is combined with the same basic treatment protocol as the intervention group, including standard medical management and 30 minutes of daily speech therapy (5 days per week).",[14,20],"Other: Sham Electroacupuncture",[22,27,31],{"type":6,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"Electroacupuncture","Electroacupuncture: Performed using a KWD-808I electroacupuncture device, set at a frequency of 2 Hz and an intensity of 2 mA.\n\nAcupoint Formula: Xuanzhong (3 cun above the apex of the lateral malleolus) and Tongli (1 cun above the transverse crease of the wrist, on the radial side of the flexor carpi ulnaris tendon).\n\nProcedure: Needles are inserted rapidly to achieve deqi, with a retention time of 20 minutes per session.",[9],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Basic treatment + Speech therapy","Participants receive standard basic treatment (management of blood pressure, lipids, blood glucose, and antiplatelet therapy) alongside speech therapy (30 minutes\u002Fsession, 5 days\u002Fweek for 4 weeks).",[9,16],{"type":6,"name":32,"description":33,"armGroupLabels":34,"otherNames":26},"Sham Electroacupuncture","Performed using the same electroacupuncture device, but with the intensity set to 0 mA to maintain blinding.\n\nInsertion Sites: Non-acupoint 1 (1 cm lateral to the Xuanzhong point towards the fibula) and Non-acupoint 2 (1 cm medial to the Tongli point towards the ulna).\n\nProcedure: Needles are inserted rapidly without deqi manipulation, with a retention time of 20 minutes per session.",[16],[36],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Linh T Nguyen, MD, MSc","CONTACT","+84-909979717","thailinh@ump.edu.vn",[42],{"facility":43,"status":26,"city":44,"state":26,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Faculty of Traditional medicine - University of Medicine and Pharmacy at Ho Chi Minh City","Ho Chi Minh City","700000","Vietnam","VN",{"type":49,"coordinates":50},"Point",[51,52],106.62965,10.82302,{"lat":52,"lon":51},[55],{"name":56,"role":38,"phone":57,"phoneExt":26,"email":58},"Head of Department","(+84-28) 3844 2756","khoayhct@ump.edu.vn",{"type":60,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Nguyen Thai Linh","MD, MSc","100646874","effectiveness-of-electroacupuncture-at-xuanzhong-gb39-and-tongli-ht5-points-in-post-stroke-aphasia-100646874",false,"NCT07684781","Effectiveness of Electroacupuncture at Xuanzhong (GB39) and Tongli (HT5) Points in Post-Stroke Aphasia","Evaluation of the Effectiveness of Electroacupuncture at Xuanzhong (GB39) and Tongli (HT5) Acupoints in Patients With Post-Stroke Aphasia","Inclusion Criteria:\n\n* Age: 18 to 75 years.\n* Diagnosis: Diagnosed with post-stroke aphasia (PSA) based on the Ministry of Health criteria or ICD-10 codes (I60-I64).\n* Cognitive and Functional State: Alert and able to cooperate with the treatment.\n* Language Assessment: Aphasia classified as moderate or mild according to the BDAE scale (scores 2-4).\n* Disease Duration: Stroke occurring 7 to 90 days prior to enrollment.\n* Language Proficiency: Native Vietnamese speaker.\n* Informed Consent: Must voluntarily sign the informed consent form and agree to comply with all study requirements.\n\nExclusion Criteria:\n\n* Non-Stroke Related Aphasia: Pre-existing aphasia or aphasia not caused by a stroke.\n* Severe Comorbidities: Severe heart, liver, or kidney failure.\n* Psychiatric\u002FCognitive Disorders: Diagnosed dementia or other mental health conditions.\n* Medical Contraindications: Presence of a pacemaker.\n* Dermatological Conditions: Infection at the targeted acupoint sites.\n* Sensory Impairment: Significant hearing or visual impairment that interferes with assessment.","ALL","18 Years","75 Years",{"count":74,"type":75},30,"ESTIMATED","INTERVENTIONAL",[78],"NA","Post-stroke aphasia (PSA) is a prevalent and debilitating condition that significantly impairs communication, social participation, and quality of life, often leading to increased long-term healthcare costs and psychological burden. While speech therapy is the recommended standard of care, many patients face limitations in recovery, prompting exploration into integrative approaches. Traditional medicine, particularly electroacupuncture, has shown potential in enhancing neuro-functional recovery; however, further evidence is needed to optimize its integration with standard rehabilitative protocols. This study evaluates the clinical efficacy of electroacupuncture at the Xuanzhong (GB39) and Tongli (HT5) acupoints combined with standardized speech therapy, aiming to improve language outcomes and patient quality of life.\n\nThe goal of this clinical trial is to evaluate the clinical efficacy of electroacupuncture at the Xuanzhong (GB39) and Tongli (HT5) acupoints combined with speech therapy in patients with post-stroke aphasia, aged 18 to 75. The main questions it aims to answer are:\n\n* Does electroacupuncture at the Xuanzhong and Tongli acupoints, combined with speech therapy and standard treatment, improve language recovery more effectively than the standard protocol alone, as measured by the BDAE and ART scales?\n* Does this combined approach significantly improve the quality of life (SAQOL-39) and correlate with functional language recovery in post-stroke patients?\n\nResearchers will compare the intervention group (electroacupuncture at Xuanzhong and Tongli combined with basic treatment and speech therapy) to a control group (electroacupuncture at other acupoints combined with basic treatment and speech therapy) to see if the specific acupoint combination enhances language rehabilitation.\n\nParticipants will:\n\n* Undergo 4 weeks of electroacupuncture (once daily, 5 days per week) and speech therapy sessions.\n* Complete assessments of language function (BDAE, ART) and quality of life (SAQOL-39) at baseline, 2 weeks, 1 month, and 3 months.\n* Be monitored for any adverse effects, such as local pain, bleeding, bruising, or needle fainting, throughout the trial period.",[81,82],"Post-stroke Aphasia","PSA",[84,23,85,86,87],"Post-stroke aphasia","Speech therapy","Language recovery","Clinical trial","NOT_YET_RECRUITING","2026-06-29",{"date":91,"type":92},"2026-07-06","ACTUAL",{"date":94,"type":75},"2026-07",{"date":96,"type":75},"2028-01",{"name":5,"class":6},1]