[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100647891":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":33,"centralContacts":37,"locations":47,"responsibleParty":64,"collaborators":32,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":32,"eligibilityCriteria":72,"healthyVolunteers":68,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":32,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":85,"overallStatus":91,"whyStopped":32,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Riphah International University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Autogenic drainage","EXPERIMENTAL","The participants in this group will be instructed to sit comfortably with the neck slightly extended and clear the upper airways by huffing or blowing the nose. Autogenic drainage begins with slow diaphragmatic breathing at low lung volumes, followed by a 3-second pause and gentle high-velocity expiration with an open glottis. As secretions move upward, breathing gradually shifts to medium and high lung volumes until mucus reaches the trachea for expectoration. The cycle of breathing exercises is repeated for 15-20 minutes while suppressing unnecessary coughing.",[13],"Procedure: Autogenic drainage",{"label":15,"type":10,"description":16,"interventionNames":17},"Flutter Device (Positive expiratory pressure technique)","The participant in this group will be instructed to sit comfortably while leaning forward with elbows supported and the neck slightly extended to open the airway. The flutter device is held horizontally with a slight upward tilt and placed in the mouth. The patient inhales slowly through the nose, holds the breath for 3-5 seconds, and exhales through the flutter device slightly faster than normal. After 4-8 breaths, a deep inhalation followed by forced expiration through the device helps mobilize secretions. Breathing control is maintained, followed by coughing or huffing if needed. The procedure is repeated for 10-15 minutes.",[18],"Device: Flutter Device",[20,27],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","The patient begins by performing the diaphragmatic breathing at low lung volume inspiration will slow with a pause of three seconds allowing the collateral ventilation, and expiration will done as a sigh with an open glottis and with high velocity as possible but no forced expiration. During this low lung volume breathing, expiration will encourage to the expiratory reserve volume. When the patient feel secretions to be moving, the volume of inspiration became deeper and expiration did not go down as far as expiratory reserve volume. As the secretions moved up the bronchial tree to the large airways then the patient will ask to perform higher lung volume breathing, tidal volume to inspiratory reserve volume range. This middle to high lung volume breathing continued until the secretions will in the trachea and ready to be expectorated",[9],[25,26],"Controlled Breathing Drainage","Airway Clearance Breathing Technique",{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"DEVICE","Flutter Device","The flutter device will hold horizontally and tilted slightly upwards to get maximal oscillatory effect and then it was placed in the mouth. Inspiration was done through the nose. A slow breath in, only slightly deeper than normal with a breath hold of 3-5 seconds will followed by breath out through the flutter device at a slightly faster rate than normal. After 4-8 breaths, a deep breath with a hold' at full inspiration will followed by a force expiration through the flutter device. This precipitated expectoration and will followed by a pause for breathing control, and then according to the subjects' preference a cough or huff was done",[15],null,[34],{"name":35,"affiliation":5,"role":36},"Arjumand Bano, MS","PRINCIPAL_INVESTIGATOR",[38,43],{"name":39,"role":40,"phone":41,"phoneExt":32,"email":42},"Muhammad Iqbal Tariq Tariq, Phd*","CONTACT","333826752","iqbal.tariq@riphah.edu.pk",{"name":44,"role":40,"phone":45,"phoneExt":32,"email":46},"Nimra noor Noor, MS-CPPT","03030684869","nimranoor358@gmail.com",[48],{"facility":49,"status":32,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Nimra Noor","Lahore","Punjab Province","40100","Pakistan","PK",{"type":56,"coordinates":57},"Point",[58,59],74.35071,31.558,{"lat":59,"lon":58},[62],{"name":63,"role":40,"phone":45,"phoneExt":32,"email":46},"Nimra Noor Noor, MS-CPPT",{"type":65,"investigatorFullName":32,"investigatorTitle":32,"investigatorAffiliation":32,"oldNameTitle":32,"oldOrganization":32},"SPONSOR","100647891","effects-of-autogenic-drainage-and-flutter-device-in-copd-100647891",false,"NCT07713043","Effects of Autogenic Drainage and Flutter Device in COPD","Comparative Effects of Autogenic Drainage and Flutter Device on Dyspnea, Pulmonary Function Test and Functional Capacity in COPD","Inclusion Criteria:\n\n* Age group: Middle age adults (40-60 years), medically stable\n* Both gender\n* Diagnosis based on GOLD criteria ((FEV₁\u002FFVC ratio \\\u003C 0.70).\n* Moderate COPD with no acute exacerbations in the past 4-6 weeks.\n* Participants must be able to perform Autogenic drainage and Flutter device physically and mentally.\n* Voluntary participation with consent.\n\nExclusion Criteria:\n\n* Cardic Diseases (Acute MI, Congestive Heart Failure)\n* Musculoskeletal Impairements\n* Using Non-invasive Ventilation\n* Recent lung diseases (Respiratory failure, pneumothorax)\n* Hemodynamic instability\n* Uncoorperative patients\n* Cognitive Impairement scale\n* Participants excluded if they did not consent\n* Comorbidities affecting exercise tolerance","ALL","40 Years","60 Years",{"count":77,"type":78},42,"ESTIMATED","INTERVENTIONAL",[81],"NA","COPD is a progressive lung disease that includes emphysema and chronic bronchitis and is a major cause of morbidity and mortality worldwide. Airway clearance techniques help improve mucus removal, reduce dyspnea, and enhance quality of life in COPD patients. This study aims to compare the effects of autogenic drainage and flutter device on dyspnea, pulmonary function, and functional capacity in patients with COPD. A randomized clinical trial will be conducted at Gulab Devi Teaching Hospital using convenient sampling. Participants will be divided into two groups: Group A will receive autogenic drainage, while Group B will use the flutter device. Interventions will be performed daily for 20-30 minutes over 6 weeks. Outcome measures will include dyspnea severity scale, spirometry, and 6-minute walk test. Data will be analyzed using SPSS with significance set at p \\\u003C 0.05. The study may provide evidence for effective, non-invasive, and cost-effective management strategies for COPD patients.",[84],"COPD (Chronic Obstructive Pulmonary Disease)",[9,86,87,88,89,90],"COPD","Dyspnea","Flutter device","Functional capacity","Pulmonary function test","NOT_YET_RECRUITING","2026-07-17",{"date":94,"type":95},"2026-07-20","ACTUAL",{"date":97,"type":78},"2026-06",{"date":99,"type":78},"2026-08-01",{"name":5,"class":6},1]