[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100654752":3},{"organization":4,"outcomesModule":7,"designInfo":24,"detailedDescription":23,"studyPopulation":23,"armGroups":31,"interventions":44,"overallOfficials":49,"centralContacts":54,"locations":60,"responsibleParty":78,"collaborators":23,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":23,"eligibilityCriteria":86,"healthyVolunteers":82,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":23,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":99,"overallStatus":62,"whyStopped":23,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":113},{"fullName":5,"class":6},"Rashid Latif Medical College","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":23,"otherOutcomes":23},[9,13,16,20],{"measure":10,"description":11,"timeFrame":12},"Balance","Balance was assessed using the Berg Balance Scale (BBS), a widely used clinical tool that evaluated functional balance through 14 tasks of varying difficulty. Each task was scored from 0-4, with a maximum score of 56. Higher scores indicated better balance, while lower scores reflected greater fall risk.","Pre intervention and 4 weeks post intervention",{"measure":14,"description":15,"timeFrame":12},"Oxygen Saturation","Oxygen saturation reflects the percentage of haemoglobin carrying oxygen, normally ranging between 95-100% in healthy individuals.",{"measure":17,"description":18,"timeFrame":19},"Respiratory rate","Respiratory rate will be measured using a pulse oximeter and recorded as the number of breaths taken per minute.","Pre-intervention and 4 weeks post-intervention",{"measure":21,"description":22,"timeFrame":19},"Heart Rate","Heart rate will be measured using a pulse oximeter and recorded as the number of heartbeats per minute.",null,{"allocation":25,"interventionModel":26,"interventionModelDescription":23,"primaryPurpose":6,"observationalModel":23,"timePerspective":23,"maskingInfo":27},"RANDOMIZED","PARALLEL",{"masking":28,"maskingDescription":23,"whoMasked":29},"SINGLE",[30],"OUTCOMES_ASSESSOR",[32,38],{"label":33,"type":34,"description":35,"interventionNames":36},"Resistance Exercise without tourniquet","ACTIVE_COMPARATOR","The control group performed the same above-mentioned resistance training without the pressure cuff under the supervision of physiotherapist.",[37],"Other: Resistance Exercise without tourniquet",{"label":39,"type":40,"description":41,"interventionNames":42},"Blood flow restriction resistance exercise","EXPERIMENTAL","Blood flow restriction resistance exercise (BFR-RE), or Kaatsu training, was developed by Dr. Yoshiaki Sato over 40 years ago. It uses a low load (15-30% 1-RM) to induce gains in muscle strength and mass. External pressure (\\~80% limb occlusion pressure, LOP) is applied via a tourniquet cuff to the proximal limb, restricting venous return while allowing partial arterial inflow, creating blood pooling in distal muscles. Training was supervised by BFR-certified physiotherapists using medium-sized cuffs, placed at the proximal thigh for a maximum of 10 minutes. Pressure was auto-adjusted to personalized LOP, inflated before the first set, maintained during rests, and deflated post-session. Each session trained a single limb, alternated on different days, 2-3 times\u002Fweek. Exercises included isotonic knee extensions from 150° to 180°: 1 set of 30 reps, then 3 sets of 15 reps, with 30-second rests, at 1-2 sec\u002Frepetition, using sandbag resistance (15-30% 1-RM).",[43],"Other: Blood flow restriction resistance exercise",[45,47],{"type":6,"name":33,"description":35,"armGroupLabels":46,"otherNames":23},[33],{"type":6,"name":39,"description":41,"armGroupLabels":48,"otherNames":23},[39],[50],{"name":51,"affiliation":52,"role":53},"Harmeen Nadeem","Arif Memorial Teaching Hospital","PRINCIPAL_INVESTIGATOR",[55],{"name":56,"role":57,"phone":58,"phoneExt":23,"email":59},"Aleena Waheed, Masters in Physical Therapy","CONTACT","03214883868","alwaheed28@gmail.com",[61],{"facility":52,"status":62,"city":63,"state":23,"zip":64,"country":65,"countryCode":66,"cosmosGeoPoint":67,"geoPoint":72,"contacts":73},"RECRUITING","Lahore","54900","Pakistan","PK",{"type":68,"coordinates":69},"Point",[70,71],74.35071,31.558,{"lat":71,"lon":70},[74,76],{"name":75,"role":57,"phone":58,"phoneExt":23,"email":59},"Aleena Waheed",{"name":77,"role":53,"phone":23,"phoneExt":23,"email":23},"Harmeen Nadeem, Doctor of Physical Therapy",{"type":53,"investigatorFullName":75,"investigatorTitle":79,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"Senior Lecturer","100654752","effects-of-blood-flow-restriction-rehabilitation-on-functional-mobility-and-balance-among-chronic-obstructive-pulmonary-disease-patients-100654752",false,"NCT07805330","Effects of Blood Flow Restriction Rehabilitation on Functional Mobility and Balance Among Chronic Obstructive Pulmonary Disease Patients.","Effects of Blood Flow Restriction Rehabilitation on Functional Mobility and Balance Among Chronic Obstructive Pulmonary Disease Patients","Inclusion Criteria:\n\n* Subjects who are clinically stable before study\n* Forced expiratory volume in 1s (FEV1)\u002Fforced vital capacity (FVC)\\\u003C70% and FEV1 ≥30% but \\\u003C80% respectively\n* Subjects who will be willing to take part in this study\n\nExclusion Criteria:\n\n* Upper abdominal surgery\n* Lung cancer\n* Open fracture\n* Mental disorder\n* Active malignancy\n* Severe hypertension","ALL","20 Years","65 Years",{"count":91,"type":92},50,"ESTIMATED","INTERVENTIONAL",[95],"NA","Background: Chronic obstructive pulmonary disease (COPD) is a common lung disease causing restricted airflow and breathing problems. It is sometimes called emphysema or chronic bronchitis. The damage results in swelling and irritation, also called inflammation, inside the airways that limit airflow into and out of the lungs. BFR Rehabilitation is effective in improving functional mobility and balance among COPD patients.\n\nObjective: To find out the effects of Blood Flow Restriction (BFR) Rehabilitation on functional mobility and balance among COPD (Chronic Obstructive Pulmonary Disease) patients.\n\nMethods: A Randomized Controlled Trial Study was conducted at Gulab Devi Hospital, Hameed Latif Hospital and Arif Memorial Teaching Hospital Lahore. Fifty patients of age 45-60 years with COPD were randomized into two groups. Allocation of patients in two equal groups by lottery method will be through random assignment. Group A was treated with controlled physical therapy while Group B was treated with BFR rehabilitation. Controlled treatment includes low intensity resistance exercises while BFR Rehabilitation includes use of a tourniquet with low intensity resistance exercises. All this information will be collected through a pulse oximeter. Berg Balance Scale will be used for balance and timed up and go test for functional mobility.",[98],"Chronic Obstructive Pulmonary Disease (COPD)",[100,101,102,103],"chronic obstructive pulmonary disease (COPD)","Blood Flow Restriction Rehabilitation","functional mobility","balance","2026-09-03",{"date":106,"type":107},"2026-09-04","ACTUAL",{"date":109,"type":107},"2026-06-24",{"date":111,"type":92},"2026-10-25",{"name":5,"class":6},1]